What is the Chinese name of Thiophene-3-ol, tetrahydro-, (3S) -?
(3S) -tetrahydrothiophene-3-ol, its name is Wuhuaxia, and it is called (3S) -tetrahydrothiophene-3-thiophene alcohol. This name comes from the convention of organic chemistry naming. Looking at this organic quality, "thiophene" is its basic ring system, the five-membered aromatic ring containing sulfur heteroatoms. "-3-ol" shows that the hydroxyl group is attached to the third carbon position of the thiophene ring. The double bonds of the "tetrahydro" epithiophene ring are all hydrogenated to form a saturated state. " ( 3S) "The three-dimensional configuration of carbon No. 3 follows the Cahn-Ingold-Prelog rule, which is determined according to the priority of connected atoms or groups. This naming is accurate, which shows that the structure and configuration of its molecules are crucial for the study and communication of organic chemistry. It makes it known to all scholars, and there is no risk of ambiguity.
What are the chemical properties of Thiophene-3-ol, tetrahydro-, (3S) -?
Thiophene-3-ol, tetrahydro-, (3S) - This substance is an organic compound with specific chemical properties. In its structure, the thiophene ring is modified by tetrahydrogens, and there are hydroxyl groups at the 3 position, with a chiral center, and the configuration is S-type.
It has the general property of alcohol, and the hydroxyl group can cause the formation of hydrogen bonds between molecules, which affects the melting point and solubility. Because of its polar hydroxyl group, it has good solubility in polar solvents such as alcohols and ethers, but poor solubility in non-polar solvents such as alkanes.
This compound also has nucleophilic properties. The hydroxyl oxygen atom has lone pair electrons, which can participate in nucleophilic substitution reactions, such as reacting with halogenated hydrocarbons to form ether compounds. Under suitable conditions, the hydroxyl group can be oxidized, such as oxidized to an aldehyde group or a carbonyl group by a mild oxidizing agent; in case of a strong oxidizing agent, or further oxidized to a carboxyl group.
Although the thiophene ring is modified by tetrahydrogens, it still has certain aromaticity and can participate in the aromatic electrophilic substitution reaction. Because the hydroxyl group is an ortho and para-site locator, the electrophilic reagent or mainly attacks the ortho or para-site of the carbon connected to the thiophene ring and the hydroxyl group.
In addition, the presence of chiral centers makes the compound optically active, which may have potential applications in asymmetric synthesis and chiral drug development. Due to its chirality, it may exhibit different reactivity and selectivity when interacting with the chiral
What are the main uses of Thiophene-3-ol, tetrahydro-, (3S) -?
Thiophene-3-ol, tetrahydro-, (3S) - is widely used. In the field of pharmaceutical synthesis, it is often used as a key intermediate. Due to its specific three-dimensional configuration and chemical structure, it can participate in a variety of chemical reactions, help build complex drug molecular structures, and then be used to develop new drugs, which is of great significance for the treatment of diseases.
In the field of organic synthesis chemistry, it also plays an important role. A series of organic compounds with special properties can be derived through many chemical reactions, such as substitution reactions, oxidation reactions, etc., providing raw material support for materials science and other fields. The chemical activity of this compound allows it to interact ingeniously with a variety of reagents to build novel organic molecules to meet the needs of material properties in different application scenarios.
In the field of fine chemicals, it also shows unique value. Or it can be used as an additive to add specific products to improve product performance, such as enhancing product stability and enhancing reactivity, etc., to provide assistance for the improvement of the quality of fine chemical products.
Therefore, thiophene-3-ol, tetrahydro-, (3S) - has important uses in many fields and has far-reaching impact on the development of related industries.
What are the preparation methods of Thiophene-3-ol, tetrahydro-, (3S) -?
There are many ways to prepare (3S) -tetrahydrothiophene-3-ol. One method can also be started from a suitable enol ether. The enol ether can be obtained by specific reaction conditions, such as in a suitable solvent and catalyzed by a suitable catalyst. After a series of steps such as addition and rearrangement, the target product can be obtained. In the meantime, the choice of solvent is quite important, and it needs to be adapted to the reactants and catalysts, so as not to interfere with the reaction process and promote the smooth progress of the reaction.
Another method, or it can be started from a thiophene derivative with a suitable substituent. The reduction reaction with a specific reagent requires fine regulation of reaction temperature, pressure and other conditions. If the temperature is too high or too low, it can cause more side reactions and reduce the yield; improper pressure also affects the reaction rate and product purity. By gradually modifying the substituent, and then reducing and other operations, the thiophene ring is hydrogenated and the hydroxyl group is introduced to obtain (3S) -tetrahydrothiophene-3-ol.
Furthermore, the method of biosynthesis can be used. Find enzymes or microorganisms with specific catalytic activity, and use suitable substrates as raw materials in a mild biological environment. The method of biocatalysis has mild conditions and high selectivity, which can avoid many side reactions in traditional chemical synthesis. However, it is necessary to pay attention to cultivating suitable biological systems to ensure the activity of enzymes or microorganisms, so as to facilitate efficient synthesis of target products.
Thiophene-3-ol, tetrahydro-, (3S) - What are the precautions in storage and transportation?
Thiophene-3-alcohol, tetrahydro-, (3S) - This substance is in storage and transportation, and many matters should be paid attention to.
The first to bear the brunt is related to storage. Because of its specific chemical properties, be sure to choose a cool, dry and well-ventilated place. If placed in a high temperature and humid place, it may cause deterioration, cause its chemical structure to change, or damage its quality and utility. And it should be kept away from fire and heat sources to avoid the risk of fire and explosion. Cover because of its flammability, a little carelessness will cause disaster.
Furthermore, when storing, the packaging must be tight. To prevent contact with air, moisture and other substances, chemical reactions occur. Packaging materials also need to be carefully selected, and should not react with thiophene-3-alcohol, tetrahydro-, (3S) -to ensure their stability.
As for transportation, it should not be underestimated. The means of transportation must be clean and dry, and there must be no residual substances that may react with them. During transportation, the temperature should be strictly controlled to maintain a suitable temperature range to avoid sudden changes in temperature affecting its properties.
And the transportation process should be smooth to prevent violent vibration and collision. Because it may be fragile or prone to chemical changes due to external forces, violent vibration and collision may cause packaging damage, which may lead to dangerous situations such as leakage. Once leaked, it will not only waste materials, but also pose a threat to the environment and personal safety.
The escort personnel also need to be professionally trained to be familiar with the characteristics of thiophene-3-ol, tetrahydro-, (3S) -and emergency treatment methods for emergencies. In this way, the storage and transportation are guaranteed to be safe.