Thiophene 3 Boronic Acid Pinacol Ester
quinoline thiophene imidazole thiazole

Thiophene-3-boronic acid pinacol ester

Taiy Chemical

Specifications

HS Code

688792

Chemical Formula C10H15BO3S
Molecular Weight 226.099
Appearance White to off - white solid
Melting Point 76 - 80 °C
Boiling Point N/A (decomposes before boiling)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
Solubility In Water Insoluble in water
Density N/A
Flash Point N/A
Stability Stable under normal conditions, moisture - sensitive
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General Information
Frequently Asked Questions
What is the main use of thiophene-3-boronic acid pinacol ester?
Borax, cold and salty in nature, its main usage, covers the following ends.
First, it can be used as medicine to treat diseases. In the medical tract, borax has the ability to clear away heat and detoxify. In case of sore throat, borax is often used by doctors. "Compendium of Materia Medica" says: "Borax, sweet and slightly salty in taste, cool in breath, and non-toxic. Its properties are soft hardware, remove scale and greasy, treat choking and nausea, build-up and blood stasis, pterygium, and mouth and teeth diseases." The throat is the main way of the human body, and it is easy to be invaded by heat toxins, causing swelling and pain that are difficult to swallow. Borax can relieve this heat toxin, reduce swelling and relieve pain, and restore the throat to unobstructed. If there are sores in the mouth, borax can also play a role. With its ability to clear heat and detoxify, it relieves the pain of sores and promotes the healing of sores.
Second, borax also has its uses in alchemy and refining. In the ancient alchemy techniques, borax was often used to assist ore smelting. It can reduce the melting point of ore and make metal components easier to separate and purify. For example, although the specific operation of borax in alchemy is not detailed in "Baopuzi Nei", borax did play an important role in ancient alchemy practice, helping alchemists to refine more refined elixir ingredients. When burning metal, borax can prevent the oxidation of metal surfaces, making metal products more smooth and durable.
Third, in daily production processes, borax is also indispensable. For example, when making certain glazes, adding borax can make the glaze smoother and brighter, and can enhance the adhesion between the glaze and the surface of the utensil. In the printing and dyeing industry, borax can be used as a mordant to help the dye adhere better to the fabric, making the dyeing more uniform, firm, and longer-lasting.
What are the synthesis methods of thiophene-3-boronic acid pinacol ester?
The synthesis methods of mercury-3-borax acetol esters are as follows:
First, boronation is used to replace boranes, and in the solution of alcohol, the two are reversed. This reverse process, boronation is used to replace boranes first. The solution of the alcohol can effectively promote the reaction, and provide the required environment for the reaction, so that the reaction is in the direction of the formation of borax acetol esters. In contrast, it is necessary to control the reaction degree. Generally, it is appropriate to maintain the reaction rate at a low temperature, such as 0-10 degrees Celsius. Due to the high temperature, it is easy to cause side reactions, and the recovery rate of the product is affected.
Second, the borate ester is used as a raw material, and the reaction is carried out under the action of catalysis. Commonly used catalysts include Lewis acids, such as boron trifluoride ethyl ether complexes. Lewis acid can activate the boron atoms in borate esters, making it easier to generate nuclei and replace the reaction. This reaction is usually carried out under inert conditions, such as nitrogen environments, to avoid the reaction of oxygen, water, etc. in the air. The reaction degree depends on the activity of the catalyst and the properties of the reaction. The reaction degree varies from 50 to 80 degrees Celsius.
Third, the borane derivative of the alcohol is reversed under the reaction. The reaction can be made of carbonate, oxidation, etc. The effect of antioxidant is to promote the activity of borane derivatives, make boron atoms more stable, and easily generate antioxidants from the alkyl alcohol. In this reverse process, it is necessary to pay attention to the dosage of antioxidant, and the amount of antioxidant may lead to other side reactions, so the amount of refined antioxidant is required. Antioxidant can be used for antioxidant non-soluble antioxidants, such as dimethylformamide (DMF), etc., which can effectively dissolve antioxidants and antioxidants, and promote antioxidants.
What are the physical properties of thiophene-3-boronic acid pinacol ester
Borax, its physical properties are quite special. Borax is white in color, often in the shape of crystals, and it is clear in appearance. Its shape is either block or granular, and the quality is slightly brittle, and it feels slippery to the touch.
Borax has a certain hardness, but it is slightly inferior to gold stones. Its density is moderate, and when weighed in the hand, it has a feeling of sinking. And borax has a slight luster under light, although it is not dazzling, it also shows its uniqueness.
In addition, the solubility of borax is also considerable. When it comes into contact with water, it can slowly dissolve, giving the water liquid some special properties. In hot water, it dissolves more rapidly, and when the water is cooled, crystals may be seen to reappear, which is a wonderful physical change.
The melting point of borax is also not very high. After proper heating, it gradually melts into a liquid state, just like ice and snow melting when warm. And when it melts, if it is cooled again, it can return to a solid state, but its shape may be slightly different from the original.
Borax can also generate electricity when rubbed, which is not a common phenomenon, but it is also one of its physical characteristics. Such various physical properties make borax useful in many fields, or used in process production, or used in medicine, all due to its uniqueness.
What are the precautions for the storage and transportation of thiophene-3-boronic acid pinacol ester?
Arsenic is also a highly toxic thing. When storing and transporting, many precautions must not be ignored.
When storing, choose the first place. When looking for a dry, cool and well-ventilated place, away from fire and heat sources, the cover is easy to evaporate due to heat, causing poisonous gas to overflow and endangering the surroundings. And it must be stored separately from acids, alkalis and edible chemicals, etc., and must not be mixed to prevent chemical reactions from occurring and generating more poisons. In addition, the storage place must be locked, managed by special personnel, and approached by strict and unrelated people, so as not to accidentally touch and misuse, leading to disaster.
When transporting, extreme caution is also required. Special transportation tools must be used, and the tools must be strictly inspected to ensure that there is no risk of leakage. Transport personnel should also be professionally trained to be familiar with the characteristics of arsenic and emergency treatment methods. During transportation, make sure that the container is stable, avoid collisions and bumps, and prevent the container from being damaged and arsenic leaking. If a leak occurs unfortunately, do not panic. Immediately evacuate the surrounding crowd, seal the scene, and report to the relevant departments at the same time, and the professionals will handle it properly.
In addition, whether it is storage or transportation, the relevant records should be detailed, such as quantity, source, whereabouts, etc., for future inspection. This is all about human life safety. Don't be slack. You must always be vigilant and strictly abide by the norms to ensure the safety of one party.
What is the market price range for thiophene-3-boronic acid pinacol ester?
"The frequency of arsenic-3-acetic acid is slow and urgent, and its price range is related to the supply and demand of the product, the distance of the land, and the quality."
Arsenic, a toxic product in the city, is generally avoided by ordinary people, but it is sought by specific users in medicine, chemical industry, etc. Its price is variable. If the production area is close and abundant, the price may be slightly cheaper, ranging from tens to hundreds of dollars per catty; if it is shipped far away, and the quantity is thin, the price will jump, or to hundreds of dollars per catty.
And acetic acid, useful for food and work. For food, seasoning and color; for work, as raw materials. In the ordinary market, those who are pure in quality are about 200 to 500 yuan per bucket; those who are inferior in quality, the price is halved. The need for acetic acid is often demanded by restaurants and workshops, and the supply and demand change, and the price also changes.
These two, one poison and the other is widely used, and the price is subject to a multi-square system, either slow or urgent. The market is impermanent, and the price is also impermanent, all changing with the world's conditions.