Thiophene 3 4 Diamine Dihydrochloride
quinoline thiophene imidazole thiazole

thiophene-3,4-diamine dihydrochloride

Taiy Chemical

Specifications

HS Code

413587

Chemical Formula C4H4S(NH2)2·2HCl
Molecular Weight 197.10
Appearance White to off - white solid
Solubility In Water Soluble
Solubility In Organic Solvents Moderately soluble in some polar organic solvents
Melting Point Typically in a certain temperature range (data needs precise experimental determination)
Pka Value Relevant to its basic amine groups, values related to each amino group's protonation (data needs precise experimental determination)
Density Needs experimental determination
Stability Stable under normal storage conditions, but may react with strong oxidizing agents
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General Information
Frequently Asked Questions
What are the main uses of thiophene-3,4-diaminodihydrochloride?
"Arsenic-3,4-diaminodiphenyl ether dianhydride has a wide range of uses. It is an important raw material for organic synthesis and has made outstanding contributions to the field of polymer materials."
In the modern chemical industry, this material is indispensable when preparing high-performance polymers. Because it can participate in the polymerization reaction, it introduces a specific structure into the polymer, thereby improving the heat resistance and mechanical properties of the material. For example, in the synthesis of polyimide, Pi-3,4-diaminodiphenyl ether dianhydride is often a key monomer. Polyimide has excellent thermal stability, chemical stability and electrical insulation. It is widely used in high-end fields such as aerospace and electronic information. The structural components of aviation and aircraft, and the printed circuit boards of electronic equipment all rely on its excellent performance.
In addition, in the coating industry, it also has important functions. The paint made from this material has good adhesion to the substrate, wear resistance and corrosion resistance. It can be applied to the surface of metals, wood and other materials to provide long-term protection. For example, protective coatings for bridges and ships are widely used.
In the field of medicinal chemistry, although not directly used in medicine, it is an important intermediate for the synthesis of some compounds with special physiological activities. Chemists use its unique structure to build complex molecular structures to explore new drugs and contribute potential to human health.
From this point of view, Pi-3,4-diaminodiphenyl ether dianhydride has key uses in many fields, and it is a treasure of chemical materials, promoting technological progress and development in various industries.
What are the physical properties of thiophene-3,4-diaminodihydrochloride?
"Tiangong Kaiwu" is a treasure of ancient scientific and technological books in our country, which details the techniques and physical properties of all kinds of creations. In today's words, and "phthalene-3,4-dicarboxylic anhydride", its physical properties are allowed to be described in ancient sayings.
Phthalene-3,4-dicarboxylic anhydride, the appearance is often white crystalline, just like frost and snow condensation, the texture is delicate and uniform. It flickers under the light, like a pearl and jade glow, and it looks quite pure.
This thing has a high melting point. If it is heated by fire, it needs to reach a certain temperature before it melts. When it melts, it is like a solid ice that meets warmth and slowly melts into a liquid, but the required temperature is very considerable. As for the boiling point, it is also not low. If you want to make it boil and vaporize, you need to apply strong heat to make it rise into a gaseous state.
The solubility of phthalene-3,4-dicarboxylic anhydride in water is not good, and it is like a stone sinking into the abyss when entering the water. It is difficult to blend with the water, and it seems that it does not disturb each other with the water. However, in some organic solvents, it can gradually disperse and dissolve, just like salt entering a soup, quietly disappearing into the invisible, showing the affinity of different media.
Furthermore, the density of this object is larger than that of ordinary objects, and when held in the hand, it feels quite heavy, as if it contains endless strength. And its stability is also impressive. Under normal conditions at room temperature, it can maintain its own shape and nature for a long time, and it is not easy to change. It is like a humble gentleman, calm and composed, and unmoved by the outside world.
Is the chemical property of thiophene-3,4-diaminodihydrochloride stable?
Alas! In order to know whether the chemical properties of this 5- (3,4 -diaminodiphenyl ether) dibenzodiazole diacid are stable, it is necessary to investigate carefully.
The stability of the chemical substance is related to its structure, bond energy and many other factors. Among the molecular structures of this 5- (3,4 -diaminodiphenyl ether) dibenzodiazole diacid, the benzene ring structure is relatively stable, and the conjugate system of the benzene ring can cause electron cloud averaging, reducing the molecular energy and thus increasing its stability.
Furthermore, the dibenzodiazole structure has a special cyclic conjugate, and this conjugate system can also stabilize the molecule. And although the ether bond -O - is relatively active, it is affected by the electronic effect of the surrounding benzene ring and other structures, and its activity degree may be suppressed.
As for the carboxyl-COOH group, it has a certain acidity and can participate in the reaction under specific conditions. However, under normal conditions, if the environment is relatively mild and there is no strong oxidant, reducing agent or specific catalyst, the carboxyl group of this 5- (3,4-diaminodiphenyl ether) dibenzoxazole diacid can also remain relatively stable.
And its amino-NH ², which has a certain alkalinity, can react with acids and the like. However, in a suitable environment, if there are no substances that can easily react with it, it can also maintain a relatively stable state.
Overall, under mild conditions at room temperature, room pressure and without the interference of special chemical reagents, the chemical properties of 5- (3,4-diaminodiphenyl ether) dibenzoxazole diacid can be said to be stable. However, if placed in high temperature, strong acid-base or specific reaction system, its chemical reaction may occur due to the action of active groups in the structure, and the stability will change accordingly.
What are the synthesis methods of thiophene-3,4-diamine dihydrochloride?
To prepare glutaric acid-3,4-diethyl ester disodium salt, you can start from the following ways.
First, glutaric acid is used as the starting material. Glutaric acid is first esterified with ethanol under the condition of catalyzed by concentrated sulfuric acid and heated. This is a reversible reaction. In order to make the reaction proceed in the direction of forming esters, ethanol should be excessive, and the water generated by the reaction should be evaporated in time to obtain diethyl glutarate. Then, under the action of basic reagents such as sodium alcohol, diethyl glutarate in a suitable organic solvent, the hydrogen on its methylene will be replaced by sodium to form glutaric acid-3,4-diethyl ester disodium salt. In this process, the alkalinity of sodium alcohol needs to be appropriate. If the alkalinity is too strong, it is easy to cause side reactions, and if the alkalinity is too weak, the reaction will be difficult to proceed.
Second, the carbon chain can be constructed by the substitution reaction of halogenated hydrocarbons. Select suitable halogenated hydrocarbons, such as 1,3-dihalopropane and diethyl malonate to undergo nucleophilic substitution under alkaline conditions. The methylene of diethyl malonate has a certain acidity, and a carbon negative ion is formed under the action of strong bases such as sodium alcohol. The carbon negative ion undergoes nucleophilic substitution of the halogen atom of 1,3-dihalopropane to form a substitution product first. After that, the product is hydrolyzed, acidified, and then esterified. Finally, the hydrogen on the methylene is replaced by sodium under alkaline conditions, and the target product can also be obtained. This route has a little more steps, but if the halogenated hydrocarbons and reaction conditions are properly selected, the yield and selectivity can be improved.
Third, the Dickman condensation reaction is used. If a suitable diester compound can be found, under the action of alkaline reagents such as sodium alcohol, a condensation reaction occurs in the molecule to form a cyclic β-ketoate, and then through hydrolysis, acidification, decarboxylation and other steps, and finally esterified with ethanol and replaced with sodium under alkaline conditions, the synthesis of the target product is also expected to be achieved. However, this method is more demanding on the structure of the reactants, and it is necessary to precisely design the structure of the reactants in order to proceed smoothly.
What are the precautions for thiophene-3,4-diaminodihydrochloride in storage and transportation?

For the first time, please pay attention to the following matters.
For the first time, it is necessary to be dry and good. If this compound encounters moisture, it is easy to absorb and hydrolyze, causing its properties to be low, so the dryness of the surrounding air is very important. And the best way to avoid harmful damage and keep its chemical properties.
Times and packaging. It must be made of dense containers. Containers made of glass or specific plastic materials are commonly used to prevent the intrusion of moisture in the air. Sealing must be tight to prevent leakage. On the way, it is also necessary to keep the package intact and prevent it from being damaged by shocks and collisions.
Furthermore, the degree of control cannot be ignored. The degree of sensitivity of this compound is not sensitive, and it is not suitable for storage. It should be kept in a low temperature, and it should not be exposed to high temperature. High temperature is easy to cause its decomposition or acceleration to be reversed, and the product is not subject to damage. Usually at a normal or slightly lower temperature, it should be determined according to its physicochemical properties.
In addition, it should also be stored in isolation. It is not oxidizing, original substances and common. Because of its acidity, it is easy to cause neutralization and reaction in case of acid; in case of oxidation or original damage, it may also lead to strong reaction, endangering safety.
It is difficult to do so in an appropriate way. According to its dangerous characteristics, comply with the relevant laws and regulations, and people. The handling process needs to be handled and placed to avoid rough operation.
Therefore, the storage of glutaric acid-3,4-dianhydride-glutaric anhydride should be paid attention to in terms of environment, packaging, temperature, storage and storage methods to ensure its safety.