Thiophene 2 5 Dicarboxylic Acid
quinoline thiophene imidazole thiazole

Thiophene-2,5-dicarboxylic acid

Taiy Chemical

    Specifications

    HS Code

    603457

    Name Thiophene-2,5-dicarboxylic acid
    Molecular Formula C6H4O4S
    Molar Mass 188.16 g/mol
    Appearance White to off - white solid
    Melting Point 300 - 304 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Acidity Dicarboxylic acid, acidic
    Odor Odorless
    Stability Stable under normal conditions
    Pka1 3.45
    Pka2 4.39

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    General Information
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    Frequently Asked Questions

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    What are the main uses of thiophene-2,5-dicarboxylic acid?
    "Tiangong Kaiwu" says: "Alum is in the shape of five colors, sulfur is the general of a group of stones, and it is all changed by fire." In today's words, Pi-2,5-dicarboxylic acid, this is a chemical substance. Its use is quite extensive, in the chemical industry, often used as a raw material for organic synthesis.
    In the process of organic synthesis, Pi-2,5-dicarboxylic acid can participate in many reactions to build complex organic molecular structures. For example, it can esterify with alcohols under suitable conditions to generate corresponding ester compounds. Such esters have important uses in flavors, coatings and other industries. In fragrances, the ester can give it a unique aroma; in coatings, its film-forming performance and durability can be optimized.
    Furthermore, in the field of medicinal chemistry, Pi-2,5-dicarboxylic acid also has potential value. Its structural properties enable it to be used as a key intermediate for the synthesis of drug molecules with specific biological activities. After reasonable chemical modification and modification, effective drugs for specific diseases may be developed, contributing to human health and well-being.
    At the same time, in the field of materials science, polymer materials prepared from this as raw materials may exhibit unique physical and chemical properties. For example, in the synthesis of some functional polymer materials, the introduction of Pi-2,5-dicarboxylic acid structural units can adjust the mechanical properties, thermal stability and electrical properties of the materials, thereby meeting the needs of different fields for the special properties of materials.
    However, it is important to note that many of the compounds related to arsenic are toxic. When using and handling arsenic-2,5-dicarboxylic acid, strict safety procedures and operating guidelines must be followed to prevent harm to humans and the environment. In this way, it is possible to make full use of its uses while ensuring safety and sustainable development.
    What are the physical properties of thiophene-2,5-dicarboxylic acid?
    In "Tiangong Kaiwu", glutaric acid-2,5-diester is a genus of organic compounds. Its physical properties are particularly important, related to its use and properties, and let me come one by one.
    Glutaric acid-2,5-diester is often liquid at room temperature, and it is clear and transparent in appearance, like glass, with good fluidity, and it flows like a stream. Its color is pure, almost colorless. This pure appearance is very critical in many fine chemical and pharmaceutical preparations, and the quality of products can be guaranteed to be pure and free.
    Smell, glutaric acid-2,5-diester has a special smell, not pungent and unpleasant smell, but it is also unique. Although this smell is not rich and fragrant, it is one of its characteristics. When identifying this substance, it can be used as an important marker.
    Furthermore, the boiling point of glutaric acid-2,5-diester has a fixed number. Under a specific pressure, it will boil and vaporize at a certain temperature. This boiling point value provides accurate parameters for its separation, purification and application to high-temperature reaction systems. The melting point is also an important physical property. When the temperature drops to a certain value, the liquid glutaric acid-2,5-diester solidifies into a solid state. This solid state has a relatively uniform texture, which brings different considerations for storage and transportation.
    Glutaric acid-2,5-diester exhibits good solubility in organic solvents. Common organic solvents such as ethanol and ether can be soluble with it, just like water emulsion. This property makes it unique in the field of organic synthesis, as a reaction medium or a component participating in the reaction. In water, its solubility is relatively limited, and the difference must be carefully considered when separating and purifying processes and designing related chemical reaction paths. The density of glutaric acid-2,5-diester is also a key physical quantity, which is slightly heavier than water. In the mixed system, it will be distributed according to this characteristic. This characteristic is of guiding significance in the operation process of chemical production such as stratification and extraction, and helps craftsmen and scholars to accurately control the reaction process and product separation.
    What are the chemical properties of thiophene-2,5-dicarboxylic acid?
    "Tiangong Kaiwu" is a scientific and technological masterpiece written by Song Yingxing in the Ming Dynasty. Today, you can answer your question about the chemical properties of 5,2-dichlorobenzoic acid with classical words.
    5,2-dichlorobenzoic acid, the appearance is often white to light yellow crystalline powder, with a certain smell. It is acidic, because the carboxyl group (-COOH) can weakly ionize hydrogen ions (H 🥰) in water, which can neutralize with bases. In case of sodium hydroxide (NaOH), sodium 5,2-dichlorobenzoate and water are formed. The solubility of this salt in water is better than that of 5,2-dichlorobenzoic acid itself.
    The chlorine atom (Cl) of 5,2-dichlorobenzoic acid is more active and can undergo a substitution reaction. If under appropriate conditions, the chlorine atom can be replaced by other groups. If attacked with nucleophiles, chlorine atoms can be replaced by hydroxyl (-OH) and amino (-NH ²) to form corresponding derivatives. This reaction can be used to prepare a variety of organic compounds, which is of great significance in the field of organic synthesis.
    This compound can also participate in esterification reactions. Under acid catalysis, its carboxyl groups can react with alcohols to form 5,2-dichlorobenzoate and water. The resulting esters often have a special aroma and can be used in the fragrance industry or as intermediates in organic synthesis.
    In oxidation-reduction reactions, 5,2-dichlorobenzoic acid is relatively stable, but under the action of strong oxidants, carboxyl groups may be further oxidized, or chlorine atoms may be oxidized to high-valent chlorine-containing compounds. On the contrary, in case of strong reducing agent, chlorine atoms may be reduced and removed to form benzoic acid derivatives. The chemical properties of
    5,2-dichlorobenzoic acid make it widely used in medicine, pesticides, dyes and other industries. Through clever use of its reaction characteristics, many high-value-added fine chemicals can be prepared.
    What are the synthesis methods of thiophene-2,5-dicarboxylic acid?
    "Tiangong Kaiwu" says: "To make phthalene-2,5-dicarboxylic acid, there are various methods. First, start with o-xylene and go through oxidation. Put o-xylene in a special kettle, add an appropriate amount of catalyst, pass oxygen, control the temperature to a suitable degree, and slowly react. In this process, the methyl group of o-xylene is gradually oxidized to obtain o-2,5-dicarboxylic acid. The key to the reaction is the precise preparation of the catalyst and the delicate control of the temperature and heat, otherwise, the yield and purity will be affected.
    Second, naphthalene is used as the source. Naphthalene is first converted through specific steps, the necessary groups are introduced, and then the oxidation reaction is carried out. Under the action of specific reagents, the structure of naphthalene is gradually transformed, and the oxidizable part is introduced, and then the oxidation method is applied, just like the oxidation of o-xylene, and the conditions are carefully regulated to convert the naphthalene into o-2,5-dicarboxylic acid. This approach requires quite high requirements for the selection of reagents and the sequence of reaction steps, and it is difficult to obtain a pure product with a slight difference.
    Third, the structure of o-2,5-dicarboxylic acid can be constructed by multi-step reaction from other related compounds. However, this path is often more complicated, and it is necessary to be familiar with various reaction mechanisms and skilled in the connection of steps in order to be successful. In short, the production of phthalates - 2,5 - dicarboxylic acid, various methods have their own advantages and disadvantages, according to the actual situation, to weigh the availability of raw materials, cost, yield and purity requirements, choose the good one and use it.
    What is the price range of thiophene-2,5-dicarboxylic acid in the market?
    Looking at the market in this world, the price of 5- (2-chloroethyl) -2-thiophenecarboxylic acid varies for many reasons. Its price often moves with changes in supply and demand, differences in quality, and changes in manufacturing costs.
    If there are many people in the market who want this product, but the supply is small, the price will rise; conversely, if the supply exceeds the demand, the price will fall. As for quality, the better one is expensive, and the second one is cheap. This is also common sense. Furthermore, the manufacturing cost is also a major factor. If the price of raw materials rises and the cost of craftsmanship increases, the price will also rise.
    As far as I know, the price of this product is probably between hundreds and thousands of yuan per kilogram. However, this is only an approximation, and the actual price should be determined by the current market conditions and the negotiation between buyers and sellers. Market conditions are fickle, and if you want to know the exact price, you must carefully observe the real-time market news and discuss it with various merchants.