Thiophene 2 2 Nitrovinyl
quinoline thiophene imidazole thiazole

Thiophene, 2-(2-nitrovinyl)-

Taiy Chemical

    Specifications

    HS Code

    463885

    Chemical Formula C6H5NO2S
    Appearance Solid

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    General Information
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    Frequently Asked Questions

    As a leading Thiophene, 2-(2-nitrovinyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical property of Thiophene, 2- (2-nitrovinyl) -
    2 - (2 - nitrovinyl) thiophene is also an organic compound. It has unique chemical properties. In terms of reactivity, the thiophene ring in the molecule interacts with the 2 - (2 - nitrovinyl) part. The thiophene ring is aromatic, but compared with the benzene ring, its electron cloud distribution is different, resulting in uneven electron density on the ring, so in the electrophilic substitution reaction, it presents a specific reaction check point and activity. In the
    2- (2-nitrovinyl) part, the nitro group has strong electron absorption, which makes the carbon-carbon double bond electron cloud biased towards the nitro group, which reduces the density of the double bond electron cloud and makes it more vulnerable to nucleophilic reagents in nucleophilic addition reactions. And the presence of nitro groups also affects the polarity of molecules and plays a role in their physical properties such as solubility. This compound may undergo specific reactions such as rearrangement and decomposition under conditions such as light and heat. When exposed to light, the electron transition in the molecule may cause changes in the structure; when heated, if it reaches a certain temperature, the nitro group may initiate reactions such as elimination. It can be used in organic synthesis to build more complex organic molecular structures, providing a raw material basis for research in materials science, medicinal chemistry, and other fields. By grasping its chemical properties, accurate synthesis of target products can be achieved.
    What are the physical properties of Thiophene, 2- (2-nitrovinyl) -
    2 - (2 -nitrovinyl) thiophene, is a kind of organic compound. Its physical properties are as follows:
    Looking at its appearance, under room temperature and pressure, or a yellow to orange solid, this color state is due to the conjugated system contained in its molecular structure. The conjugated structure causes the electron transition energy level to change, and then absorbs visible light of a specific wavelength, so it shows this color.
    As for the melting point, it is about 80-85 ° C. The value of the melting point is closely related to the intermolecular force. The compound has van der Waals force and dipole-dipole interaction between molecules, and the specific structure gives its intermolecular force a corresponding strength, so it presents this melting point range. When the temperature rises to the melting point, the molecule is energized enough to overcome the intermolecular force, the lattice structure is destroyed, and then the solid state is converted to the liquid state.
    In terms of boiling point, under normal pressure environment, it is about 280-290 ℃. The boiling point also depends on the size of the intermolecular force. Because of its relatively large molecular weight and relatively complex molecular structure, the intermolecular force is strong, and the molecule needs higher energy to break free from the liquid phase and become the gas phase, so the boiling point is higher.
    In terms of solubility, 2- (2-nitrovinyl) thiophene is slightly soluble in water. Water is a polar solvent, and although this compound contains polar groups, the overall molecular structure is not highly polar. According to the principle of "similarity and miscibility", the force between it and water molecules is weak and it is difficult to dissolve in water. However, it is soluble in organic solvents such as dichloromethane, chloroform, and tetrahydrofuran. The polarity of these organic solvents is more compatible with the compound, and the molecules can form moderate interactions to dissolve it.
    The density of this compound is about 1.3 - 1.4 g/cm ³. The density reflects the mass per unit volume of a substance and is determined by its molecular structure, molecular weight, and molecular accumulation method. Its specific structure and composition give rise to such density values that density is an important consideration when operations such as mixing or separating the substance from other substances are involved.
    What is the main use of Thiophene, 2- (2-nitrovinyl) -?
    2 - (2 - nitrovinyl) thiophene has a wide range of uses. It is often a key intermediate in the field of organic synthesis. It can be derived from a variety of chemical reactions, such as reduction reactions, or products containing nitrogen and with different characteristics, which is of great significance in the creation of new drugs and functional materials.
    In materials science, 2 - (2 - nitrovinyl) thiophene also has important uses. Polymer materials made from this as raw materials may have unique electrical and optical properties. Due to the conjugated system of nitro and thiophene rings in its structure, it may endow the material with excellent photoelectric properties, which can be used to prepare organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices to improve their luminous efficiency and photoelectric conversion efficiency.
    Furthermore, in the field of pharmaceutical chemistry, the unique structure of this compound may have certain biological activity. Scientists can explore and develop new drugs by modifying its structure to deal with various diseases, such as antibacterial, anti-cancer, etc. There are potential applications. In summary, 2 - (2-nitrovinyl) thiophene has important uses in organic synthesis, materials science, pharmaceutical chemistry and other fields, and has broad prospects.
    What are the synthesis methods of Thiophene, 2- (2-nitrovinyl) -
    The method of preparing 2 - (2 - nitrovinyl) thiophene has been known for a long time, and there are many wonderful methods.
    First, it can be obtained by the condensation reaction of thiophene with the precursor of nitroolefin. In this method, thiophene is prepared first, which is the root of the reaction. Suitable nitroolefin precursors are also found, such as nitro-containing halogenated hydrocarbons or nitroalcohols. Place the two in a suitable reaction environment, such as choosing an appropriate solvent, organic solvents, toluene, dichloromethane, etc. are available. And add suitable catalysts, alkali catalysts can often promote this reaction, such as potassium carbonate, sodium hydroxide and the like. Control the reaction temperature and time, under moderate warm conditions, such as 40-60 degrees Celsius, after several hours of reaction, the reactants interact to produce 2- (2-nitrovinyl) thiophene. After the reaction is completed, the product is purified by conventional separation and purification methods, such as extraction, column chromatography, etc.
    Second, there are also thiophene derivatives as starting materials. First, the thiophene is modified so that a specific substituent is attached to a certain position. This substituent can be used as a key when nitrovinyl is introduced later. Then, through a series of organic synthesis steps, such as nucleophilic substitution, elimination reaction, etc., the structure of 2 - (2-nitrovinyl) thiophene is gradually constructed. This process requires careful planning of each step of the reaction to ensure the smooth progress of each step. The reagents used and the reaction conditions also need to be precisely controlled, and the temperature, time, and reagent dosage of each step are all related to success or failure. After multiple steps of reaction, the impurities are also carefully separated and purified, and the final product of pure 2 - (2-nitrovinyl) thiophene is obtained.
    Thiophene, 2- (2-nitrovinyl) - what are the precautions during use
    2 - (2 - nitrovinyl) thiophene is an important compound in organic synthesis, and there are many key precautions that need to be paid attention to during use.
    First, it is related to its chemical properties. This compound contains thiophene ring and nitrovinyl group, which has specific reactivity. Because of its carbon-carbon double bond and nitro group, it is prone to addition and oxidation reactions. Therefore, when storing and using, it is necessary to avoid strong oxidants, strong acids and bases, etc., to avoid violent reactions and lead to safety accidents. For example, if it comes into contact with strong oxidants such as high concentrations of hydrogen peroxide, it is very likely to cause combustion or even explosion.
    Second, safety cannot be ignored. 2 - (2 - nitrovinyl) thiophene may be toxic and irritating. When operating, be sure to take personal protection. Wear appropriate protective clothing, such as lab clothes, and protective gloves to avoid direct contact with the skin. At the same time, wear goggles to prevent it from accidentally splashing into the eyes and causing damage to the eyes. Furthermore, the operation should be carried out in a well-ventilated environment, such as a fume hood, to prevent inhalation of its volatile gaseous substances, so as not to damage the respiratory system.
    Third, in terms of operating practices. When taking the compound, the dosage should be precisely controlled. According to the experimental or production needs, with the help of suitable metering tools, such as balances, pipettes, etc., to avoid waste and reduce latent risk. When participating in a chemical reaction, it is necessary to strictly control the reaction conditions, such as temperature, reaction time, and the proportion of reactants. If the temperature is too high or the reaction time is too long, or the side reactions increase, which affects the purity and yield of the product.
    Fourth, storage conditions are critical. Store 2 - (2 - nitrovinyl) thiophene in a cool, dry and ventilated place, away from fire and heat sources. At the same time, it should be sealed and stored to prevent it from reacting with oxygen and moisture in the air and causing deterioration. If stored improperly, it will not only affect its own quality, but may also cause accidents in subsequent use.