Thieno 3 2 B Thiophene 2 Carboxylic Acid
quinoline thiophene imidazole thiazole

thieno[3,2-b]thiophene-2-carboxylic acid

Taiy Chemical

    Specifications

    HS Code

    382621

    Name thieno[3,2-b]thiophene-2-carboxylic acid
    Chemical Formula C7H4O2S2
    Molar Mass 184.24 g/mol
    Appearance Solid (usually white or off - white powder)
    Melting Point 230 - 234 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO, DMF
    Pka Typically around 3 - 4 (estimated for carboxylic acid group)
    Odor Odorless or very faint odor
    Stability Stable under normal conditions but may react with strong oxidizing or reducing agents

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    Frequently Asked Questions

    As a leading thieno[3,2-b]thiophene-2-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of thiopheno [3,2-b] thiophene-2-carboxylic acid
    In "Tiangang Kaiwu", beggar alkene and [3,2-b] beggar alkene-2-carboxylic acid are special compounds. Its physical properties are unique.
    The color state of this compound, at room temperature, is a crystal clear solid state, just like ice and snow carved, and it is pleasing to the eye. Its texture is delicate and warm to the touch, but it does not lose the firmness of the solid state.
    When it comes to the melting point, after careful study and careful measurement, it is about [X] degrees Celsius. When the temperature gradually rises to the melting point, this compound is like ice in spring, slowly melting into a clear liquid, like a clear spring, with sparkling light in the flow.
    Its boiling point also has a specific value, which is about [X] degrees Celsius. At the boiling point, the liquid rapidly changes to a gaseous state, curling and rising, like a cloud, showing a wonderful landscape of material state transformation.
    The density of beggar and [3,2-b] beggar-2-carboxylic acids, carefully measured, is about [X] grams per cubic centimeter. This density makes it exhibit unique floating properties in a specific environment. In liquids, it may float or sink, following the laws determined by its own material properties.
    In terms of solubility, this compound exhibits good solubility in organic solvents, such as ethanol, ether, etc. It can be fused with these organic solvents to form a uniform and stable solution. However, in water, its solubility is very small, almost insoluble. On the water surface, it either floats like oil or sinks to the bottom of the water, and the interface with the water is clearly discernible, like a distinct state.
    The physical properties of beggar and [3,2-b] beggar-2-carboxylic acids are revealed in addition to their chemical nature, laying a solid foundation for in-depth exploration of their chemical properties and practical applications.
    What are the chemical properties of thiopheno [3,2-b] thiophene-2-carboxylic acids
    < Br >
    This compound is acidic because it contains carboxyl groups. In the carboxyl group, the carbonyl group is connected to the hydroxyl group, and the electron cloud is biased towards the carbonyl group, which makes the hydrogen in the hydroxyl group easy to dissociate and acidic. It can interact with bases such as sodium hydroxide to form carboxylates and water, just like "acid and base meet, and turn into salt and water".
    In addition, its quinoline ring also has unique properties. The quinoline ring is aromatic, and the π electron cloud is distributed above and below the ring, making it relatively stable. The electron cloud density distribution on the ring is uneven, resulting in different reactivity at different positions. In the electrophilic substitution reaction, due to the electron-withdrawing effect of nitrogen atoms, the electron cloud density is relatively high in the meta-position, and the electrophilic reagents tend to the meta-position, which is "electron density, the tendency of conduction reaction".
    And in [3,2-b] quinoline-2-carboxylic acid, the carboxyl group and the quinoline ring interact. The electron-withdrawing effect of the carboxyl group may reduce the electron cloud density of the quinoline ring, weaken its aromaticity, and affect the electrophilic substitution reaction activity; conversely, the quinoline ring also has an effect on the acidity of the carboxyl group, or enhances or weakens the acidity of the carboxyl group, which is "the two are involved, and the properties change." < Br >
    Because of its nitrogen-containing heterocyclic ring and carboxyl group, it can be used as a ligand to complex with metal ions. The lone pair electrons on the nitrogen atom and the oxygen atom can be supplied to the metal ions to form coordination bonds and form complexes. This process is like "yin and yang, complexing and forming". It may have applications in catalysis, materials and other fields, and its complexing properties can be used to regulate reactions and improve material properties.
    What is the common synthesis method of thiopheno [3,2-b] thiophene-2-carboxylic acid?
    Alas! If you want to know the common synthesis method of quinolino [3,2-b] quinoline-2-carboxylic acid, it is the key to organic synthesis. This synthesis method often follows various paths.
    First, the method of nucleophilic substitution can be borrowed. With a substrate containing a specific functional group, under suitable conditions, the nucleophilic reagent is attacked and the substitution reaction is induced to gradually form the structure of this quinolino [3,2-b] quinoline-2-carboxylic acid. For example, the active halogenated aromatic hydrocarbons are selected, and the nitrogen-containing nucleophiles are heated and reacted in an organic solvent under the catalysis of a base. The partial structure of quinoline is initially established, and then the carboxylation and other subsequent steps are added. Carboxyl groups are added to the final product.
    Second, the cyclization reaction is also a common method. Using compounds with suitable carbon chains and functional groups as starting materials, through intramolecular cyclization, a fused quinoline structure is constructed. Or under the action of a specific catalyst, the double bonds, carbonyl groups and other functional groups in the molecule interact, and a cyclization reaction occurs to form the core skeleton of this quinoline and [3,2-b] quinoline, which is then modified to introduce carboxyl groups.
    Third, the reaction catalyzed by transition metals is also quite effective. For example, the cross-coupling reaction catalyzed by palladium can precisely connect different organic fragments. Using aryl halide and alkenyl borate as raw materials, under the joint action of palladium catalyst, ligand and base, the formation of carbon-carbon bonds is achieved, and the structure of the target molecule is gradually established. After carboxylation modification, the quinolino [3,2-b] quinoline-2-carboxylic acid is obtained.
    All these synthesis methods require careful selection and fine regulation according to the characteristics of the substrate, the reaction conditions and the purity requirements of the product, etc., in order to achieve the purpose of efficient synthesis.
    In which fields are thiopheno [3,2-b] thiophene-2-carboxylic acids used?
    "Tiangong Kaiwu" says: "This product is widely used in various domains." Glutaraldehyde [3,2-b] glutaraldehyde-2-carboxylic acid is used in many fields such as medicine, chemical industry, and materials.
    In the field of medicine, it shows unique efficacy. This acid has good sterilization and disinfection properties and can be used for the disinfection of medical apparatus. Because medical apparatus is related to the safety of patients and has strict requirements for disinfection, this acid can efficiently kill all kinds of bacteria, and its properties are relatively stable. It can be stored for a long time under suitable conditions. Therefore, it is commonly used in hospital operating rooms, wards and other places to ensure the health and safety of the medical environment.
    In the chemical industry, this acid is also an important raw material. In organic synthesis, with its special chemical structure, it can participate in many reactions to prepare a variety of complex organic compounds. For example, in the synthesis of some fine chemicals, this acid can be used as a key intermediate to build a molecular framework of the target product through specific reaction steps, which helps to enrich the variety and performance of chemical products.
    In the field of materials, glutaraldehyde [3,2-b] glutaraldehyde-2-carboxylic acid also contributes. It can be used for surface modification of materials, and the acid-related groups are attached to the surface of the material through chemical reactions to change the surface properties of the material, such as improving the hydrophilicity and biocompatibility of the material. In terms of biomedical materials, when the modified materials come into contact with biological tissues, they can reduce the risk of immune reactions and improve the stability and functionality of the materials in vivo.
    From this perspective, glutaraldehyde [3,2-b] glutaraldehyde-2-carboxylic acid has significant uses in the fields of medicine, chemical industry and materials, and is an indispensable chemical substance.
    What is the market price of thiopheno [3,2-b] thiophene-2-carboxylic acid?
    What I am asking you is to inquire about the market price of [3,2-b] [3,2-b] [1,2-carboxylic acid]. However, the relevant market conditions of this product vary from time to time, and are related to many factors such as quality, source, and transaction scale. It is difficult to determine its price.
    In commercial shops, the price of various goods often fluctuates due to changes in supply and demand, differences in materials, and simplicity of craftsmanship. This [3,2-b] [3,2-b] [1,2-carboxylic acid, if its quality is good and the preparation method is good, its price may decrease; if mass production is abundant and oversupply, the price may decrease.
    Furthermore, the market in different regions has different prices due to differences in logistics and taxation. In prosperous cities, transactions are convenient and information is smooth, and its price may be relatively flat; in remote places, transportation is difficult, costs are increased, and the price may be higher.
    In addition, this compound may be used for scientific research, pharmaceuticals, etc., and different uses have different requirements for its purity, and the price will also change accordingly. For exquisite scientific research experiments, it needs extremely high purity, and its price must be expensive; for ordinary industrial preparation, the purity requirements are slightly lower, and the price may be slightly cheaper.
    Therefore, if you want to know the exact market price, you should carefully investigate the market situation, consult the chemical raw material merchants, traders, or study it carefully on professional trading platforms and industry information offices, in order to obtain a more accurate price.