S Alpha 2 Dimethylamino Ethyl 2 Thiophenemethanol
quinoline thiophene imidazole thiazole

(S)-alpha-[2-(Dimethylamino)ethyl]-2-thiophenemethanol

Taiy Chemical

    Specifications

    HS Code

    832504

    Chemical Name (S)-alpha-[2-(Dimethylamino)ethyl]-2-thiophenemethanol
    Molecular Formula C9H15NOS
    Molecular Weight 185.29
    Appearance Typically a solid or viscous liquid (description may vary)
    Melting Point Specific value would need further research
    Boiling Point Specific value would need further research
    Solubility Solubility characteristics in different solvents would need research
    Density Specific density value would need research
    Pka Specific pKa value would need research
    Chirality Has (S)-configuration

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    General Information
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    Frequently Asked Questions

    As a leading (S)-alpha-[2-(Dimethylamino)ethyl]-2-thiophenemethanol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of (S) -alpha- [2- (Dimethylamino) ethyl] -2-thiophenemethanol?
    The chemical structure of (S) -alpha - [2- (dimethylamino) ethyl] -2-thiophene methanol is like an exquisitely constructed miniature pavilion. The center of this compound is the thiophene ring, which is like a delicate framework of pentagons. It is cleverly connected by four carbon atoms and one sulfur atom. The atoms on the ring are in their respective positions, just like the stars in the sky, echoing each other and maintaining the stability of the structure.
    At the second position of the thiophene ring, there is a key side chain connected. The start of the side chain is α-carbon, and this carbon is like a hub, connecting the thiophene ring with subsequent groups. Extracted from alpha-carbon, one is connected to the hydroxyl group (-OH), which is like a flexible antenna, giving the compound a specific reactivity and polarity. On the other side, is connected to the [2- (dimethylamino) ethyl] group. This ethyl group is like a bridge, connected to alpha-carbon at one end and dimethylamino at the other end. Dimethylamino is composed of a nitrogen atom and two methyl groups. The presence of methyl groups is like a solid foundation, enhancing the lipid solubility and steric resistance of the molecule. On the whole, the chemical structure of (S ) - α - [ 2 - (dimethylamino) ethyl] -2 -thiophene methanol is complementary and exquisite. Because of its unique atomic arrangement and group combination, it endows this compound with unique physical and chemical properties. It has important research value and potential application prospects in many fields such as organic synthesis and medicinal chemistry.
    What are the main uses of (S) -alpha- [2- (Dimethylamino) ethyl] -2-thiophenemethanol?
    (S) -alpha - [2- (dimethylamino) ethyl] -2-thiophene methanol, this is an organic compound with a wide range of uses. In the field of medicine, it is often a key intermediate in drug synthesis. With its unique chemical structure, it can participate in the construction of many drug molecules, which has a great impact on drug activity and efficacy. For example, some compounds with specific pharmacological activities can be precisely synthesized through a series of chemical reactions to treat specific diseases.
    In the field of organic synthesis chemistry, it is also an important synthetic building block. Because its structure contains active groups, it can react with many reagents to construct complex organic molecular structures, which provides convenience for organic synthesis chemists to create novel compounds and help expand the types and properties of organic compounds.
    In the field of materials science, it may be applied to the preparation of functional materials by appropriate chemical modification. For example, by compounding with specific polymers or other materials, the material is endowed with special properties, such as improving material solubility and enhancing material stability, thereby expanding the scope of material applications.
    In short, (S) -alpha - [2- (dimethylamino) ethyl] -2-thiophenomethanol has important value and wide application prospects in many fields such as medicine, organic synthesis and materials science.
    What are the physical properties of (S) -alpha- [2- (Dimethylamino) ethyl] -2-thiophenemethanol?
    (S) -alpha - [2- (dimethylamino) ethyl] -2-thiophene methanol is one of the organic compounds. Its physical properties are quite characteristic.
    Looking at its properties, under normal circumstances, it is mostly white to off-white crystalline powder. This state is easy to store and use, and the fineness of the powder is related to its dispersion in subsequent reactions and the efficiency of participating in the reaction.
    When it comes to the melting point, it is within a certain range. This melting point characteristic provides an important indicator for identifying this compound and considering its purity. Because the melting point of the pure product is relatively fixed, if it contains impurities, the melting point may be deviated or the melting range may be widened. < Br >
    In terms of solubility, it shows a certain solubility in common organic solvents, such as ethanol and chloroform. In ethanol, it can be moderately dissolved, which is conducive to uniformly dispersing it in the reaction system with ethanol as a solvent and participating in various chemical transformations. In water, the solubility is poor, and this difference is closely related to the hydrophilicity of the groups contained in the molecular structure. The combined action of dimethylamino, thiophene ring and other structures in the molecule causes it to exhibit different solubility in different solvent environments.
    Looking at its density, although there is no exact value, it is speculated that its density may be similar to that of common organic compounds based on the structure of similar compounds. This density data has important reference value when it comes to operations such as mixing and separation of substances, and is related to the stratification and flow characteristics of different substances.
    In addition, the stability of this compound is also a key physical property. Under normal environmental conditions, if properly stored, it is not affected by extreme factors such as high temperature, strong light and high humidity, and can maintain a relatively stable state. In case of special conditions, such as strong acid, strong alkali environment, or high temperature for a long time, the molecular structure may change, affecting its original properties and functions. These physical properties play a pivotal role in its synthesis, storage and application.
    What are the synthesis methods of (S) -alpha- [2- (Dimethylamino) ethyl] -2-thiophenemethanol?
    The synthesis method of (S) -alpha - [2- (dimethylamino) ethyl] -2-thiophene methanol has been known for a long time, and has been improved by many excellent explorations, and has gradually become complete.
    The first method is to use thiophene as the starting source. First, thiophene is reacted with a halogenated alkane under specific catalysts and reaction conditions to obtain 2-substituted thiophene. This substituent is then condensed with a carbonyl-containing compound, such as aldehyde or ketone, in an alkaline medium to form a key intermediate. Subsequently, the intermediate is aminated with dimethylamine in a suitable solvent and temperature, and dimethylamino is introduced. Finally, the obtained product is reduced, and the carbonyl group is converted into methanol group with a reducing agent to obtain (S) -alpha - [2- (dimethylamino) ethyl] -2-thiophene methanol.
    Second, 2-thiophene formaldehyde is used as the initial material. First, it is combined with a compound with active hydrogen under alkali catalysis to generate the corresponding enolate, and then nucleophilic substitution reaction occurs with halogenated ethylamine, and the 2- (dimethylamino) ethyl fragment is successfully introduced. Then, using a suitable reducing agent, such as sodium borohydride or lithium aluminum hydride, the aldehyde group is reduced to methanol group to obtain the target product. In this process, it is necessary to pay attention to the precise control of the reaction conditions. Temperature, pH and reaction time are all related to the yield and purity of the product.
    Third, there is also a strategy of using thiophene derivatives as starting materials to construct target molecules through multi-step reactions. First, through selective functional group conversion, a suitable substituent on the thiophene ring is constructed, and then through cyclization, amination and reduction steps, step by step, to achieve the synthesis of (S) -alpha - [2- (dimethylamino) ethyl] -2-thiophenylmethanol.
    All kinds of synthesis methods have their own advantages and disadvantages, and they need to be carefully selected according to actual needs, such as the availability of raw materials, cost considerations, and product purity requirements, in order to achieve twice the result with half the effort.
    (S) -alpha- [2- (Dimethylamino) ethyl] -2-thiophenemethanol What are the precautions in storage and transportation?
    (S ) -α - [ 2 - (dimethylamino) ethyl] -2 -thiophene methanol, this is a very important chemical substance, during storage and transportation, many key matters need to be paid special attention.
    First of all, the storage place must be dry and cool. This substance is afraid of moisture and moisture. If it is placed in a humid place, it is very susceptible to moisture and deterioration, causing its chemical properties to change and affect subsequent use. And if the temperature is too high, it will also cause many adverse conditions, or cause it to decompose and evaporate, so a cool environment is the basis for storage. Secondly, ensure that the storage place is well ventilated. Because of its volatility, if the air does not circulate, the volatile gas will gather in one place, or pose a safety hazard, and it is not conducive to its long-term storage. Furthermore, it needs to be stored separately from oxidants, acids and other substances. This substance is chemically active, and contact with the above substances may cause severe chemical reactions, resulting in serious consequences such as combustion and explosion.
    As for transportation, it is also not sloppy. Before transportation, be sure to pack tightly. The packaging should be strong and well sealed to prevent package damage and material leakage due to bumps and collisions during transportation. During transportation, temperature should be strictly controlled. Avoid sun exposure. When it is hot in summer, special attention should be paid to taking cooling measures to prevent danger caused by excessive temperature. Transportation vehicles should also be kept clean, and no oxidants, acids, etc. should remain. And transportation personnel must be professionally trained to be familiar with the characteristics of this substance and emergency treatment methods, so that in case of emergencies, they can respond quickly and properly to ensure transportation safety.