R N Methyl Gama 1 Naphthalenyloxy 2 Thiophenepropanamine
quinoline thiophene imidazole thiazole

(r)-n-methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine

Taiy Chemical

    Specifications

    HS Code

    227394

    Chemical Formula C20H21NOS
    Molecular Weight 323.45
    Physical State Solid (usually)
    Appearance Off - white to light yellow powder
    Melting Point Specific value would need experimental determination
    Boiling Point Estimated based on similar compounds
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like chloroform, methanol
    Odor May have a faint, characteristic odor
    Pka Value Related to its basic amine group, value would need experimental determination
    Logp Value Indicates lipophilicity, value would need calculation or experimental determination
    Stability Stable under normal storage conditions, but may degrade on exposure to light, heat, or air over time

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    What is the chemical structure of (R) -n-methyl-gama- (1-naphthalenyloxy) -2-thiophenepropanamine?
    (R) -N-methyl - γ - ( 1-naphthoxy) -2-thiophenopropylamine, this is the name of an organic compound. To clarify its chemical structure, it is necessary to follow the naming rules of organic chemistry.
    " (R) " shows that this compound is chiral and has an R configuration, which is related to the specific arrangement of atoms or groups in the molecule in space. "N-methyl" means that there is a methyl group ($- CH_3 $) attached to the nitrogen atom. " Gamma- (1-naphthoxy) ", γ indicates the position of the substituent, starting from the carbon atom connected to the thiophene ring, through the three carbon atoms at the γ position, this position is connected with 1-naphthoxy, that is, the 1 position of the naphthalene ring is connected to the oxygen atom and then connected to the main chain." 2-thiophenopropylamine "indicates that the main chain is a propylamine structure ($CH_3CH_2CH_2NH_2 $), and the thiophene ring is connected to the carbon atom at position 2 of the propylamine main chain.
    Its chemical structure is roughly as follows: propylamine chain as the group, thiophene ring at the 2nd position, 1-naphthoxy group at the γ position, and methyl group at the nitrogen atom. The thiophene ring has a sulfur-containing heterocyclic structure of a five-membered ring, and the naphthalene ring is a fused diphenyl ring structure. The structure of this compound fuses the aromatic ring structures such as thiophene and naphthalene, as well as functional groups such as amine groups and alkoxy groups. These structural characteristics may endow it with specific physical, chemical and biological activities.
    What are the main uses of (R) -n-methyl-gama- (1-naphthalenyloxy) -2-thiophenepropanamine?
    (R) -N-methyl-gamma- (1-naphthoxy) -2-thiophenylpropylamine, this is an organic compound. Its main use is crucial in the field of medicinal chemistry.
    In the process of drug development, it is often used as a lead compound. Due to its specific chemical structure and biological activity, researchers hope to modify and modify it to create novel and effective drugs. For example, in the development of drugs for neurological diseases, its unique structure may interact with neurotransmitter receptors to regulate nerve conduction, or bring hope for the treatment of Parkinson's disease, Alzheimer's disease and other related diseases.
    In the field of organic synthesis, it is also an important intermediate. By virtue of the various activity checking points in its structure, more complex compound structures can be constructed by various organic reactions. Such as borrowing nucleophilic substitution, addition reactions, etc., adding different functional groups, expanding the variety of compounds, paving the way for the development of organic synthetic chemistry, promoting the creation of new substances, in materials science and other related fields or derived from other applications, such as the preparation of materials with special photoelectric properties.
    What are the physical properties of (R) -n-methyl-gama- (1-naphthalenyloxy) -2-thiophenepropanamine?
    (R) -N-methyl - γ -( 1-naphthoxy) -2-thiophenopropylamine, the physical properties of this substance are as follows:
    Its appearance is mostly white to off-white crystalline powder. In terms of melting point, it is about a specific temperature range, which is one of the key indicators to determine its purity and characteristics. There are subtle differences in different purity and crystal form or melting point. < Br >
    In terms of solubility, it shows a certain solubility in organic solvents such as ethanol and chloroform, and can be better dissolved, so that it can be uniformly dispersed in the organic synthesis reaction system, which is conducive to the smooth progress of the reaction; however, the solubility in water is poor, which is related to the hydrophobicity of the functional groups contained in its molecular structure. Intramolecular naphthoxy, thiophenyl and other groups have strong hydrophobicity, making it difficult to dissolve in water with strong polarity.
    Density is also an important physical property. Although the exact value needs to be determined under specific experimental conditions, in general, the density fluctuates within a certain range based on its molecular composition and structural characteristics. This property is of great significance when it comes to material measurement, mixing and process design, and is related to the accuracy of the reaction system ratio and subsequent product separation and purification operations.
    In addition, its stability is good under conventional environmental conditions, but it is necessary to avoid extreme conditions such as light, high temperature, and high humidity. The molecular structure changes caused by light or luminescent chemical reactions; high temperature, high humidity environment or promote hydrolysis, oxidation and other reactions, which affect its quality and performance.
    The above physical properties are all key factors to consider when researching, producing and applying this compound, and are of great significance for controlling its quality, optimizing the reaction process and determining the applicable scenarios.
    What are the synthesis methods of (R) -n-methyl-gama- (1-naphthalenyloxy) -2-thiophenepropanamine?
    The synthesis method of (R) -n-methyl - γ - ( 1-naphthoxy) -2-thiophenopropylamine has been used in ancient times, and after several generations of research, there are many methods today.
    First, start with 1-naphthol as a group, supplemented by an appropriate base, so that it interacts with haloalkanes to obtain 1-naphthoxy alkanes. This step requires careful temperature control and the selection of a suitable solvent to promote a smooth reaction. For example, using dimethylformamide as a solvent, in a warm environment, the reaction is quite efficient. In the second case, thiophene is used as raw material and halogenated to obtain halogenated thiophene. Then, it is reacted with metal magnesium to prepare Grignard reagent. The Grignard reagent is combined with the carbonyl derivative of the above-mentioned 1-naphthoxy alkane, and the key intermediate can be obtained after addition and hydrolysis. In this process, the preparation of Grignard reagent needs to avoid water, and the conditions for addition reaction need to be precisely controlled.
    Furthermore, the obtained intermediate is aminated with methylamine under appropriate catalyst and reaction conditions. In this step, a metal catalyst can be selected, and the amino group can be successfully substituted under mild temperature and pressure to obtain (R) -n-methyl - γ - ( 1-naphthoxy) -2-thiophenylpropylamine. However, the maintenance and control of chirality is very important, and special chiral additives or catalysts are often needed to maintain the high purity configuration of the product.
    The whole process of synthesis requires careful control of the reaction conditions at each step, from the quality of the raw material to the temperature, time and agent of the reaction, all of which are related to the yield and purity of the product. All kinds of details are the key to the synthesis of this compound, and proper management can achieve satisfactory results.
    What is the market outlook for (R) -n-methyl-gama- (1-naphthalenyloxy) -2-thiophenepropanamine?
    (R) -N-methyl - γ - ( 1-naphthoxy) -2-thiophenopropylamine is an organic compound. Looking at its market prospects, it has a multi-dimensional phase and is closely related to many fields.
    In the field of pharmaceutical research and development, organic compounds are often the key cornerstones. (R) -N-methyl - γ - ( 1-naphthoxy) -2-thiophenopropylamine may have unique chemical structures and biological activities, which can attract the attention of medical researchers. It may provide an opportunity for the creation of new drugs. If in-depth pharmacological research and clinical trials are conducted, it may emerge in the treatment of specific diseases, such as neurological diseases, cardiovascular diseases, etc. Taking many organic compounds in the past as an example, through exquisite research and development, they have become good medicines for treating diseases and saving people. This compound may also follow this trajectory and gain a place in the pharmaceutical market.
    In the field of chemical materials, it may have the potential to participate in the synthesis of special materials. With its own chemical properties, it may become a key raw material for the preparation of high-performance polymers and functional materials. Today, the chemical industry has an increasing demand for new materials. If this compound can demonstrate its effectiveness in this field, it will surely usher in a broad market space. For example, some special structural organic compounds have become the core components of electronic and optical materials after rational application, and help the development of related industries. (R) -N-methyl - γ - ( 1-naphthoxy) -2-thiophenopropylamine is also expected to open up in this regard.
    However, its market prospects also face challenges. The complexity of the synthesis process or the high production cost will affect market competitiveness. And before being introduced to the market, it needs to pass strict regulatory review and security evaluation. But in general, if we can overcome the technical problems and meet the regulatory requirements, (R) - N - methyl - γ - ( 1 - naphthoxy) - 2 - thiophenopropylamine or shine in the fields of medicine and chemical industry, the market prospect is promising.