N-(1,3-benzothiazol-2-yl)thiophene-2-sulfonamide

The chemical structure of (1,3-butadiene-2-yl) allyl-2-chlorobenzene is as follows:
This compound contains a benzene ring, which is connected with a chlorine-containing substituent at the 2-position of the benzene ring. On this substituent, there is a (1,3-butadiene-2-yl) allyl structure.
The 1,3-butadiene structure consists of four carbon atoms connected by a conjugated double bond, i.e.\ (CH_2 = CH-CH = CH_2\), where the carbon atom at the 2-position participates in the connection with the allyl group and the benzene ring. The allyl structure is\ (CH_2 = CH - CH_2 -\). Taken together, the whole substituent is connected to the carbon atom at the 2-position of the benzene ring through chemical bonds, forming the unique chemical structure of (1,3-butadiene-2-yl) allyl-2-chlorobenzene. The conjugated double bond system in this structure endows the compound with some special physical and chemical properties, such as conjugated addition reactions that may occur under certain conditions, and the benzene ring and chlorine atoms also have important effects on its properties.

(1,3-butadiene-2-yl) acrylic-2-aldehyde, that is, sorbic aldehyde, its main uses are as follows:
First, in the food field, sorbic aldehyde can be used as a food flavor. Because of its unique aroma, it can add a different flavor to food, and is widely used in the production of beverages, candies, baked goods, etc. With reasonable preparation, it can give food a pleasant aroma, improve the attractiveness and quality of food, thereby increasing consumers' desire to buy.
Second, in the pharmaceutical and chemical industry, sorbic aldehyde is an important organic synthesis intermediate. With its special molecular structure, it can participate in many chemical reactions and is used to synthesize various drugs and chemical products. For example, in the synthesis route of some drugs, sorbic aldehyde is used as a key starting material to build the active structure of the drug through a series of reactions, which helps the development and production of new drugs.
Third, sorbic aldehyde is also crucial in the fragrance industry. Not only can it be used as a fragrance, but it can also be used as a raw material for the synthesis of other fragrances. Because it can react with a variety of compounds to generate flavor products with diverse structures, it can meet the market demand for different flavor types of fragrances, thereby promoting the development of the fragrance industry.
Fourth, in the field of organic materials, sorbic aldehyde can participate in the synthesis of polymer materials. After polymerization, its structure is introduced into the polymer chain to change the material properties, such as improving the flexibility and stability of the material, and it is applied to the modification of plastics, rubber and other polymer materials to expand the application range of materials.

To prepare N- (1,3-benzodiazole-2-yl) -2-thiophenoformamide, the synthesis method is as follows:
Starting with 2-thiophenoformic acid as raw material, first convert it into the corresponding acid chloride. Take an appropriate amount of 2-thiophenecarboxylic acid, place it in a reaction vessel, add an appropriate amount of chlorination reagent, such as dichlorosulfoxide, and add a little N, N-dimethylformamide as a catalyst. Heat and stir the reaction at a suitable temperature (such as 50-80 ° C) for a period of time. During this process, 2-thiophenecarboxylic acid reacts with dichlorosulfoxide, and the carboxyl group is converted into an acyl chloride to generate 2-thiophenecarboxylic chloride, which is purified by distillation and other means for later use.
On the other hand, 1,3-benzodiazole-2- Take catechol as the starting material and make it react with urea under appropriate reaction conditions. Mix catechol and urea in a certain ratio (such as 1:1.2), add an appropriate amount of solvent, such as polyphosphoric acid, and cyclize at a higher temperature (such as 180-200 ° C) to generate 1,3-benzodiazole-2-one. Then, with a suitable reducing agent, such as sodium borohydride-zinc chloride system, in a suitable solvent (such as methanol), 1,3-benzodiazole-2-one is reductively aminated to finally obtain 1,3-benzodiazole-2-amine, which is separated and purified for backup.
Subsequently, the obtained 2-thiophenoformyl chloride is amidated with 1,3-benzodiazole-2-amine. In the reaction vessel, an appropriate amount of a base, such as triethylamine, is added to neutralize the hydrogen chloride generated by the reaction, and then the solution of 2-thiophenoformyl chloride is slowly added dropwise to the reaction system containing 1,3-benzodiazole-2-amine and triethylamine. The reaction is carried out at low temperature (e.g. 0-5 ° C) for a period of time, and then gradually warmed to room temperature to continue the reaction, so that the two fully react to form the target product N- (1,3-benzodiazole-2-yl) -2-thiophenoformamide. After the reaction is completed, the product is separated and purified by conventional post-processing operations, such as extraction, washing, recrystallization, etc., to obtain pure N- (1,3-benzodiazole-2-yl) -2-thiophenoformamide.

(1,3-butadiene-2-yl) acetylene-2-aldehyde, also known as butyne aldehyde, has the following physical properties:
In appearance, it may be colorless to light yellow liquid at room temperature and pressure. Due to the unsaturated bond and aldehyde structure, a certain degree of oxidation or polymerization may occur under conditions such as light and oxygen, and the color may gradually become darker. In terms of boiling point, due to the existence of van der Waals force between molecules and the weak hydrogen bonding produced by the polar group aldehyde group, its boiling point is relatively moderate, generally within a certain temperature range, and the specific value needs to be determined according to accurate experiments. However, it can be speculated that compared with alkanes with the same number of carbon atoms, the boiling point will increase due to their unsaturated structure and the polarity of the aldehyde group.
In terms of solubility, the substance has a certain polarity. According to the principle of similar dissolution, it can have good solubility in some polar organic solvents such as ethanol and acetone; however, because its carbon chain part has a certain non-polarity, its solubility in water is relatively limited, and it can only be slightly soluble or insoluble. This is because the hydrogen bond between water molecules is strong, and the ability of the substance to form hydrogen bonds with water molecules and the interaction force between molecules are not enough to cause it to dissolve in water.
The density is usually greater than that of water, which is due to the relative mass distribution of carbon atoms, hydrogen atoms and oxygen atoms in its molecular structure and the degree of close packing of molecules, so that the mass of the substance per unit volume is greater than the mass per unit volume of water.

2-Mercapto-3-butenonitrile-2-yl ether-2-oxoglutaric acid, this substance has many chemical properties. The carboxyl group in its structure is acidic and can neutralize with the base to form the corresponding carboxylate and water. In case of sodium hydroxide, 2-mercapto-3-butenonitrile-2-yl ether-2-oxoglutarate sodium salt and water will be produced.
The double bond in this substance is extremely active and can undergo addition reactions. Taking the bromine elemental substance as an example, the double bond will break, and the bromine atom will be connected to the carbon atom at both ends of the original double bond to form a dibromo product. This reaction can be used to detect the existence of double bonds. It can also participate in the polymerization reaction, and many double-bond-containing monomers are connected to each other to form a polymer. The sulfur atom in the thiol group has a lone pair of electrons, which can form a coordination bond with metal ions to form a stable complex. Like binding with mercury ions, it can be used to treat mercury-containing wastewater and remove mercury ions.
The carbonyl group of 2-mercapto-3-butenonitrile-2-yl ether-2-oxoglutaric acid has certain electrophilicity and can react with nucleophilic reagents. For example, alcohols can form acetal or ketal structures with carbonyl groups under acid catalysis, which is often used to protect carbonyl groups in organic synthesis. In short, the diverse chemical properties of this substance make it important in the fields of organic synthesis, materials science and environmental protection.