What is the chemical structure of N- (1,3-benzodioxane-5-yl) -3-chloro-6-fluoro-1-benzothiophene-2-formamide?

This is the structural description of an organic compound, and its structure can be deduced according to the naming rules. This compound is named N- (1,3-naphthaleno-dioxacyclopentene-5-yl) -3-chloro-6-fluoro-1-naphthalimidazole-2-acetamide.

The first description is the structure of naphthaleno-dioxacyclopentene. The naphthalene ring is fused with a diphenyl ring. The dioxacyclopentene is a five-membered ring containing two oxygen atoms. It is fused with the naphthalene ring at the 1,3 position and the 5-position substituent.

Furthermore, 3-chloro-6-fluoro-1-naphthalimidazole-2-acetamide part, naphthalimidazole is fused by naphthalene ring and imidazole ring, which is a five-membered heterocycle containing two nitrogen atoms. Naphthalimidazole has a chlorine atom at the 3rd position, a fluorine atom at the 6th position, and a nitrogen atom at the 1st position. This nitrogen atom is connected to an acetyl group, and the methylene of acetyl-COCH -2 - is connected to the nitrogen at the 1st position of naphthalimidazole to form a 3-chloro-6-fluoro-1-naphthalimidazole-2-acetamide fragment.

Finally, the nitrogen atom of this fragment is connected to a 1,3-naphthaleno-dioxane-5-group to obtain the complete structure of the compound. Its structure is complex, containing multiple cyclic structures and substituents, and each part is connected to each other to jointly determine the chemical properties and reactivity of the

What are the physical properties of N- (1,3-benzodioxane-5-yl) -3-chloro-6-fluoro-1-benzothiophene-2-formamide

N- (1,3-naphthaleno heterocyclopentene dioxide-5-yl) -3-fluoro-6-chloro-1-naphthalimidazole-2-acetamide is an organic compound. This compound has specific physical properties, let me say it in ancient Chinese.

Its melting point is the inherent characteristic of the substance, and its purity can be identified. After experimental investigation, the melting point of the compound is within a certain range, which varies slightly due to the difference in preparation method and purity. Generally speaking, the melting point of pure N- (1,3-naphthaleno-heterocyclopentene dioxide-5-yl) -3-fluoro-6-chloro-1-naphthalimidazole-2-acetamide is stable in a certain precise range, which is an important indicator to determine the quality of its quality.

Solubility is also a key physical property. In common organic solvents, it exhibits different solubility. In polar organic solvents such as ethanol and acetone, the compound has a certain solubility. Ethanol is a commonly used organic solvent, N- (1,3-naphthaleno-heterocyclopentene dioxide-5-yl) -3-fluoro-6-chloro-1-naphthalimidazole-2-acetamide can be dissolved in it to form a homogeneous solution, but the solubility is restricted by factors such as temperature. When heating up, the solubility may increase, which is due to the increase in temperature, the thermal movement of molecules intensifies, and the interaction between solute molecules and solvent molecules enhances.

In non-polar organic solvents, such as n-hexane, the solubility of this compound is very small. N-hexane is a typical non-polar solvent, with N- (1,3-naphthaleno-heterocyclopentene dioxide-5-yl) -3-fluoro-6-chloro-1-naphthalimidazole-2-acetamide The intermolecular force is weak, and it is difficult to overcome the intermolecular cohesion of the solute, so it is not easy to dissolve.

In addition, the density of the compound is also a specific value. Although its precise density needs to be accurately determined by professional instruments and is affected by environmental factors such as temperature and pressure, it has a relatively stable density value at room temperature and pressure, which is of great significance for its application in chemical production, drug research and development and other fields.

Its appearance is also an important physical characteristic. Pure N- (1,3-naphthalene-heterocyclopentene-dioxide-5-yl) -3-fluoro-6-chloro-1-naphthalimidazole-2-acetamide is mostly white or off-white crystalline powder with uniform texture. This appearance feature is of great reference value for the preliminary identification of this compound.

What are the common uses of N- (1,3-benzodioxane-5-yl) -3-chloro-6-fluoro-1-benzothiophene-2-formamide?

The common application path of N- (1,3-naphthalenedioxycyclopentene-5-yl) -3-chloro-6-bromo-1-naphthalenylpyrrole-2-acetic acid lies in the field of medicinal chemistry.

This compound has a unique structure. The structure of naphthalenedioxycyclopentene and naphthalenylpyrrole endows it with specific chemical properties and potential biological activities. In the process of drug development, it is often used as a key intermediate. Through clever organic synthesis methods, functional groups are added to modify its activity and selectivity to meet the needs of different disease targets.

First, in the creation of anti-tumor drugs, their structural characteristics can be used to modify and modify them to target specific receptors or signaling pathways of tumor cells, and inhibit the proliferation, invasion and metastasis of tumor cells. For example, by covalent binding, it is closely linked to the activity check points of tumor-related proteins, precisely attack tumor cells, reduce their damage to normal cells, and improve the efficacy and safety of drugs.

Second, in the development of drugs for neurological diseases, because of its structure or ability to penetrate the blood-brain barrier, it is expected to become a candidate drug for the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. After rational structural optimization, it can enhance its affinity with neurotransmitter receptors, regulate the release and transmission of neurotransmitters, improve neural function, and relieve disease symptoms.

Furthermore, in the field of anti-inflammatory drugs, through structural modification, it can regulate inflammation-related signaling pathways, inhibit the release of inflammatory mediators, and demonstrate anti-inflammatory effect. It may play an important role in the treatment of inflammatory diseases such as arthritis and inflammatory bowel disease.

In summary, N- (1,3-naphthaleno-dioxacyclopentene-5-yl) -3-chloro-6-bromo-1-naphthaleno-pyrrole-2-acetic acid is used in the field of medicinal chemistry. With its unique structure, it has broad application prospects and research value in the research and development of anti-tumor, nervous system diseases, anti-inflammatory drugs, etc., and is an important object for pharmaceutical chemists to study.

What are the synthesis methods of N- (1,3-benzodioxane-5-yl) -3-chloro-6-fluoro-1-benzothiophene-2-formamide

To prepare N- (1,3-naphthaleno-dioxacyclopentene-5-yl) -3-fluoro-6-chloro-1-naphthaleno-pyrrole-2-acetyl, there are various methods.

First, the key structure can be constructed from the starting material through a multi-step reaction. First, the naphthalene ring is modified with a suitable reagent to introduce a specific substituent. For example, by using a halogenation reaction, chlorine and fluorine atoms are introduced at the designated position of the naphthalene ring. With a halogenating agent, under appropriate reaction conditions, such as controlling the temperature, catalyst type and dosage, halogen atoms can be selectively added to the specific check point of the naphthalene ring to obtain fluorine and chlorine-containing naphthalene derivatives. < Br >
Then, the structure of 1,3-naphthaleno-dioxacyclopentene is constructed. Phenolic compounds are often reacted with dihalogenated alkanes under basic conditions to form ether bonds and then close the ring. During the reaction, the strength of the base and the polarity of the reaction solvent need to be paid attention to to to ensure the smooth progress of the reaction and control the regioselectivity.

For the formation of naphthalene-pyrrole structures, it can be formed by the condensation reaction of suitable amines and carbonyl compounds under specific conditions. In this process, the activity of the reaction substrate and the reaction conditions need to be finely regulated, so that the reaction can proceed according to the design direction and gradually build the basic skeleton of the target molecule.

Second, a convergence synthesis strategy can also be used. First, the 1,3-naphthalene-dioxacyclopentene-5-yl fragment and the 3-fluoro-6-chloro-1-naphthalene-pyrrole-2-acetyl fragment were synthesized respectively, and then the two were spliced through a suitable linking reaction. If the acylation reaction is used to react with a nitrogen-containing compound with an acyl halide or an acid anhydride to form an amide bond to connect the two fragments, this reaction needs to pay attention to the control of reactivity and side reactions, and select a suitable acid binding agent to promote the forward progress of the reaction.

In the synthesis process, the product of each step needs to be separated and purified, and recrystallization, column chromatography and other means are commonly used to ensure that the reaction proceeds in the direction of generating the target product, and the purity of the obtained product meets the requirements. Finally, N- (1,3-naphthaleno-dioxacyclopentene-5-yl) -3-fluoro-6-chloro-1-naphthaleno-pyrrole-2-acetyl is obtained.

What is the market price of N- (1,3-benzodioxane-5-yl) -3-chloro-6-fluoro-1-benzothiophene-2-formamide?

I think what you are talking about is a rather complex chemical substance. However, it is not easy to know the market price of this "N- (1,3-naphthaleno-dioxacyclopentene-5-yl) -3-fluoro-6-chloro-1-naphthaleno-pyrrole-2-formamide".

Because of its or the fine chemicals used in specific fields, the price is affected by many factors. The first one to bear the brunt is the difficulty of production. If the synthesis of this compound requires complicated steps, rare raw materials or special reaction conditions, the cost will be high, and the price will also rise.

Furthermore, the supply and demand relationship in the market is also key. If there is a high demand for this product in a particular industry and the supply is limited, the price will be high; conversely, if the supply exceeds the demand, the price will fall.

In addition, the purity of the product also affects the price. High purity products are often used in high-end scientific research, medicine and other fields, and the price is often far higher than that of ordinary purity.

However, I have not seen this product traded in the market, and there is no detailed market survey. It is difficult to determine its price. Or you need to consult merchants specializing in such chemicals, chemical trading platforms, or relevant industry experts to obtain more accurate price information.