What is the chemical structure of N- (1,1-dimethylethyl) -5- [methyl- [ (2-methyl-4-oxo-3H-quinazoline-6-yl) methyl] amino] thiophene-2-formamide?

I am looking at this question about the chemical structure of "N- (1,1-dimethylethyl) -5 - [methyl- [ (2-methyl-4-oxo-3H-pyrazolo [5,1-c] [1,2,4] triazine-6-yl) methyl] amino] pyridine-2-formamide". This is a question of structural analysis of complex compounds in the field of organic chemistry.

To understand the chemical structure of this compound, it is necessary to gradually analyze it according to the rules and nomenclature of organic chemistry. First, "N- (1,1-dimethylethyl) " indicates that a 1,1-dimethylethyl group is attached to the nitrogen atom. This group is a specific substituent composed of two methyl groups attached to the 1-position carbon of the same ethyl group.

"5 - [methyl - [ (2-methyl-4-oxo-3H-pyrazolo [5,1-c] [1,2,4] triazine-6-yl) methyl] amino]" part, connected to a complex structure at position 5 of the pyridine ring. Wherein, "methyl - [ (2 - methyl - 4 - oxo - 3H - pyrazolo [5,1 - c] [1,2,4] triazine - 6 - yl) methyl] amino", the amino group is connected with a methyl group at one end, and the other end is connected with a 2 - methyl - 4 - oxo - 3H - pyrazolo [5,1 - c] [1,2,4] triazine - 6 - group as the main body and connected to the methyl group at the 6 position structure. Pyrazolo [5,1-c] [1,2,4] triazine is a fused heterocyclic system composed of a pyrazole ring fused with a [1,2,4] triazine ring, with a methyl substitution at the 2nd position and an oxygen substitution at the 4th position.

"Pyridine-2-formamide" indicates that the main body of the compound is a pyridine ring, which is connected to a formamide group at the 2nd position. The formamide group is composed of a carbonyl group connected to an amino group, which is connected to the 2nd carbon of the pyridine ring.

In summary, this compound has a complex structure and is composed of a pyridine ring as the core, which is connected to different substituents at the nitrogen atom, the 5th position and the 2nd position, respectively. Through the interpretation of the naming of each part, the approximate appearance of its chemical structure can be constructed, but the accurate drawing needs to be aided by organic chemistry drawing specifications and software.

What are the main uses of N- (1,1-dimethylethyl) -5- [methyl- [ (2-methyl-4-oxo-3H-quinazoline-6-yl) methyl] amino] thiophene-2-formamide?

N- (1,1-dimethylethyl) -5 - [methyl- [ (2-methyl-4-oxo-3H-furano [2,3-d] pyrimidine-6-yl) methyl] amino] acetamide-2-methylfuranoic acid, which is widely used.

In the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Due to its unique molecular structure or specific biological activity, it can be chemically modified and modified to adapt to different disease therapeutic targets. For example, in the process of anti-tumor drug research and development, scientists hope to obtain highly selective and highly active anti-cancer compounds by optimizing their structures, which can inhibit the growth and spread of tumor cells by interfering with key metabolic pathways or signal transduction pathways of tumor cells.

In the field of pesticides, it also plays an important role. After rational structural design and optimization, highly efficient, low-toxic and environmentally friendly pesticides can be developed. For example, it can be designed to precisely act on the pesticide components of the pest's nervous system or digestive system according to the physiological characteristics of specific pests, achieving efficient insecticidal while reducing adverse effects on non-target organisms and the environment, and contributing to sustainable agricultural development.

In the field of materials science, due to its specific chemical properties and structures, it can be used to develop special materials. For example, by compounding with other organic or inorganic materials, giving materials new properties, such as improving the stability, optical properties or electrical properties of materials, expanding the scope of material applications, and showing potential application value in electronic devices, optical materials and other fields.

What are the physical properties of N- (1,1-dimethylethyl) -5- [methyl- [ (2-methyl-4-oxo-3H-quinazoline-6-yl) methyl] amino] thiophene-2-formamide?

Alas, this is an investigation into the physical properties of acetonitrile. Acetonitrile is a colorless, transparent and aromatic liquid. Its physical properties are particularly important.

First of all, its boiling point is about 81.6 ° C. At this temperature, acetonitrile changes from a liquid state to a gaseous state, which is quite useful in chemical operations such as distillation and separation. If you want to extract acetonitrile from the mixture, you can separate acetonitrile by heating it to about 81.6 ° C according to its boiling point.

And its melting point is -45.7 ° C. Below this temperature, acetonitrile will condense into a solid state. This melting point needs to be paid attention to during storage and transportation. If the ambient temperature is too low, acetonitrile will freeze, or it will affect the container.

The density of acetonitrile is about 0.786 g/cm ³, which is lighter than that of water. When acetonitrile is mixed with water, acetonitrile will float on water, which can be used in some liquid-liquid separation scenarios.

Its solubility is also a key physical property. Acetonitrile can be miscible with various organic solvents such as water, ethanol, and ether. This good solubility makes it an excellent solvent. In the field of organic synthesis, many reactions rely on acetonitrile to dissolve the reactants, which promotes the smooth progress of the reaction.

The dielectric constant of acetonitrile is quite high, about 37.5. This high dielectric constant endows acetonitrile with unique properties in electrolyte solutions, which is conducive to the dissolution and transport of ions, and is of great significance in application scenarios such as battery electrolytes.

In addition, acetonitrile is highly volatile and volatile as a gas at room temperature. This characteristic requires attention to ventilation during use to prevent acetonitrile vapor accumulation from causing safety problems. Because of its certain toxicity, inhalation or excessive skin contact may endanger human health. Therefore, when handling acetonitrile, it is necessary to follow safety procedures and take protective measures.

What are the synthesis methods of N- (1,1-dimethylethyl) -5- [methyl- [ (2-methyl-4-oxo-3H-quinazoline-6-yl) methyl] amino] thiophene-2-formamide?

To prepare N - (1,1 - dimethylbenzyl) - 5 - [methyl - [ (2 - methyl - 4 - oxo - 3H - pyrazolo [5,1 - c] - [1,2,4] triazine - 6 - yl) methyl] amino] acetamide - 2 - methoxybenzoic acid, the synthesis method is as follows:

The starting material should be carefully selected to ensure a smooth reaction. In the first method, the structure of 2-methyl-4-oxo-3H-pyrazolo [5,1-c] - [1,2,4] triazine-6-base can be constructed with specific organic reagents. The corresponding nitrogen-containing heterocyclic compounds can be cyclized and oxidized under suitable reaction conditions to obtain this key intermediate.

Then, the intermediate is substituted with the compound containing methyl and amino groups. In this process, the reaction temperature, pH and the ratio of the reactants need to be carefully regulated to promote the efficient generation of the target substitution product. This substitution reaction may be carried out in an organic solvent, such as dichloromethane, N, N-dimethylformamide, etc., and an appropriate amount of base may be added to promote the reaction.

As for the introduction of the 1,1-dimethylbenzyl moiety, an appropriate 1,1-dimethylbenzylation reagent can be selected to react with the above product under mild reaction conditions. This reaction may require specific catalyst assistance to improve the reaction rate and selectivity.

Finally, the resulting product is amidated and methoxybenzoate estered. Appropriate condensation agents, such as dicyclohexyl carbodiimide (DCC), can be selected for the amidation reaction to form amide bonds between the amino-containing products and the corresponding carboxylic acids. The esterification reaction of methoxybenzoic acid can be catalyzed by acid to react alcohol with methoxybenzoic acid and introduce methoxybenzoic acid groups to complete the synthesis of N - (1,1 - dimethylbenzyl) - 5 - [methyl - [ (2 - methyl - 4 - oxo - 3H - pyrazolo [5,1 - c] - [1,2,4] triazine - 6 - yl) methyl] amino] acetamide - 2 - methoxybenzoic acid. After each step of the reaction, the product needs to be purified by means such as column chromatography and recrystallization to obtain a high-purity target product.

What is the market prospect of N- (1,1-dimethylethyl) -5- [methyl- [ (2-methyl-4-oxo-3H-quinazoline-6-yl) methyl] amino] thiophene-2-formamide?

This is a chemically related description. Although the wording is obscure, I should try my best to solve it by the way of ancient Chinese.

The first sentence "N- (1,1-dimethylethyl) -5 - [methyl- [ (2-methyl-4-oxo-3H-pyrazolo [5,1 - c] [1,2,4] triazine-6-yl) methyl] amino] pyridine-2-formamide", which is a complex chemical substance. Looking at its structure, it can be seen that it is composed of multiple groups, with exquisite structure, and each group is related to each other, which affects the properties of this substance.

As for the market prospects related to this substance, it should be viewed from many aspects. In the field of scientific research, such compounds with unique structures may provide opportunities for the development of new drugs and the exploration of new materials. Its special structure or endow it with special chemical and physical properties. If it can be well researched and utilized, it may create new technologies and products.

In the pharmaceutical market, if this compound is studied to have biological activity, it can act on specific biological targets, or it can become a precursor to new drugs. Nowadays, the pharmaceutical industry has a strong demand for high-efficiency and low-toxicity new drugs. If this substance is validated by pharmacological experiments, it will definitely gain a place in the market.

In terms of chemical materials, if their stability, reactivity and other properties are suitable for the synthesis of specific materials, or can be applied to the improvement and innovation of plastics, fibers and other materials. With the development of materials science, the demand for new functional materials is increasing, and this compound may be able to meet some of these needs.

However, its market prospects are not entirely optimistic. R & D costs may be a major obstacle. From the synthesis optimization of compounds, to various performance tests, safety assessments, etc., a lot of human, material and financial resources are required. And the market competition is fierce. If similar or similar compounds have occupied the market, if they want to stand out, they must win with unique advantages.

In conclusion, this "N- (1,1-dimethylethyl) -5 - [methyl- [ (2-methyl-4-oxo-3H-pyrazolo [5,1-c] [1,2,4] triazine-6-yl) methyl] amino] pyridine-2-formamide" has potential opportunities, but it also faces many challenges. In-depth research and rational planning are required to achieve development in the market.