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What is the use of Methyl 3-methoxybenzo [b] thiophene-7-carboxylate
Methyl 3-methoxybenzo [b] thiophene-7-carboxylic acid ester has a wide range of uses. In the field of medicine, this compound may have unique pharmacological activities or can be used as a lead compound for the development of new drugs. Due to its special chemical structure, it may be able to combine with specific targets in organisms to regulate physiological processes, such as affecting enzyme activity and participating in cell signaling pathways, etc., it is expected to be used to treat diseases such as inflammation and tumors.
In the field of materials science, it also has potential applications. Because of its stable structure and specific photoelectric properties, it can be used to prepare organic optoelectronic devices, such as organic Light Emitting Diode (OLED), organic solar cells, etc. In OLEDs, it can be used as a light-emitting material to give the device unique luminous properties, improve its luminous efficiency and color purity; in organic solar cells, it can participate in the generation and transmission of photogenerated charges, helping to improve the photoelectric conversion efficiency of the battery.
In the field of chemical synthesis, this substance can be used as a key intermediate. With its active groups, a variety of compounds with different structures can be derived through various chemical reactions, providing an important starting material for the synthesis of complex organic molecules, expanding the path of organic synthesis, and helping to develop new functional materials and fine chemicals.
What are the physical properties of Methyl 3-methoxybenzo [b] thiophene-7-carboxylate
Methyl 3-methoxybenzo [b] thiophene-7-carboxylic acid ester is one of the organic compounds. Its physical properties are worth exploring.
First of all, its properties are often solid, and it may be white to light yellow powder. This is due to its molecular structure and crystalline properties. Under light, it may be slightly shiny, fine and uniform.
The melting point is about a specific temperature range. Due to the interaction of intermolecular forces, such as van der Waals force and hydrogen bonds, it begins to melt at this temperature. The determination of this melting point is crucial for the identification and purification of this compound.
The value of the boiling point is also an important physical property. When a certain temperature is reached, the substance changes from liquid to gaseous state. The boiling point is related to the relative molecular mass of the molecule, molecular polarity and the strength of intermolecular forces. Because the compound contains specific functional groups, the intermolecular forces have their own unique characteristics, and the boiling point also has corresponding characteristics.
In terms of solubility, it shows a certain solubility in organic solvents, such as common ethanol, ether, chloroform, etc. Because its molecular structure contains lipophilic groups, it can form van der Waals forces or other weak interactions with organic solvent molecules, so it can be soluble. However, its solubility in water is poor, because the overall molecular polarity does not reach the degree that it can be fully miscible with water.
Density is also one of the physical properties of the substance. The density of methyl 3-methoxybenzo [b] thiophene-7-carboxylic acid esters reflects the degree of molecular packing compactness. The exact density value can be obtained by experimental determination, which is of great significance in many fields such as chemical production and material separation.
In summary, the physical properties of methyl 3-methoxybenzo [b] thiophene-7-carboxylic acid esters, such as properties, melting point, boiling point, solubility, density, etc., are determined by their molecular structure, and play an indispensable role in many fields such as organic synthesis and drug development.
What are the chemical properties of Methyl 3-methoxybenzo [b] thiophene-7-carboxylate
Methyl-3-methoxybenzo [b] thiophene-7-carboxylic acid ester is one of the organic compounds. Its chemical properties are unique and have many remarkable characteristics.
As far as physical properties are concerned, this compound is usually in a solid state, and due to the presence of benzothiophene ring, methoxy group, carboxyl ester group and other groups in the molecular structure, its melting point, boiling point and other physical parameters are affected by the interaction of groups. The presence of methoxy groups changes the polarity and intermolecular forces of the molecule as a whole through electronic effects. Generally speaking, methoxy groups are the donator groups, which can increase the electron cloud density of the benzene ring, and then affect its solubility. In common organic solvents, such as ethanol, acetone, etc., or exhibit some solubility, but poor solubility in water, due to the strong hydrophobicity of the compound as a whole.
In terms of its chemical activity, the benzothiophene ring endows the compound with aromatic properties, enabling it to participate in many typical reactions of aromatic compounds. For example, electrophilic substitution reactions can occur, due to the electron-donning properties of methoxy groups, or the reaction check points are mainly located in the ortho and para-positions of the benzene ring. The carboxyl ester group can undergo hydrolysis reaction. Under acidic or alkaline conditions, the ester group hydrolyzes to form corresponding carboxylic acids and alcohols. In alkaline environments, the hydrolysis reaction may be more rapid and complete, because the base can neutralize the generated carboxylic acid and promote the positive reaction. At the same time, the compound may participate in the reverse reaction of esterification reaction and transesterification reaction with alcohols under specific conditions. In addition, because the molecule contains sulfur atoms, or can participate in some reactions involving the chemical transformation of sulfur atoms, its chemical properties add unique features.
What are the synthesis methods of Methyl 3-methoxybenzo [b] thiophene-7-carboxylate
The method for preparing methyl 3-methoxybenzo [b] thiophene-7-carboxylic acid esters follows a number of paths. First, it can be formed by condensation and cyclization of sulfur-containing compounds and aromatic compounds with methoxy groups. First, the two are in an appropriate reaction medium, catalyzed by a specific catalyst to make them condensate, and then cyclized to construct a ring system of benzothiophene, and then esterified to obtain the target product. Among them, the temperature, time, type and amount of catalyst of the reaction need to be precisely controlled to achieve the ideal yield and purity. < Br >
Or, starting from benzo [b] thiophene-7-carboxylic acid, it is obtained by esterification reaction with methanol under the action of esterification reagents. Commonly used esterification reagents, such as concentrated sulfuric acid, dicyclohexylcarbodiimide (DCC) and 4-dimethylaminopyridine (DMAP), etc. When concentrated sulfuric acid is used as an esterification reagent, although it is inexpensive, there are many side reactions; the combination of DCC and DMAP, the reaction conditions are mild, the yield is high, and the cost is also high.
In addition, the benzothiophene skeleton can be constructed by a metal-catalyzed coupling reaction starting from a suitable halogenated aromatic hydrocarbon, and then the methoxylation and esterification steps can be carried out. This route requires the selection of suitable metal catalysts, such as palladium, nickel, etc., and their ligands to promote the efficient progress of the reaction. Each method has its own advantages and disadvantages. When implementing, it is necessary to weigh the requirements of raw material availability, cost, yield and purity.
What is the price of Methyl 3-methoxybenzo [b] thiophene-7-carboxylate in the market?
I look at your question, but I am inquiring about the price of "Methyl 3 - methoxybenzo [b] thiophene - 7 - carboxylate" in the market. However, this compound is not a well-known ordinary product, and its price also varies due to many factors.
First, the source is different, and the price is different. If you buy it from a professional chemical reagent supplier, they need to consider the procurement cost, purification process, operating costs, etc. Those with excellent purification and reliable sources may be expensive. If the preparation process is complicated and the raw materials are scarce, the price will also rise.
Second, the amount of quantity affects the price. Usually purchased in bulk, the unit price may be reduced due to economies of scale; if only a small amount is required, the supplier may set a higher unit price due to transaction cost considerations.
Then I checked "Tiangong Kaiwu", but there is no relevant price record for this compound. As far as current information is concerned, there is no unified and clear pricing in the chemical market. To know the exact price, you need to consult professional chemical reagent sales platforms and chemical raw material suppliers, check their quotations in detail, and comprehensively compare them to obtain relatively accurate price information.