Methyl 3-Sulphonylamidocyanogenthiophene-2-carboxylate

Methyl 3-sulfonylamino cyanothiophene-2-carboxylic acid ester, this is an organic compound with a wide range of uses.
In the field of medicinal chemistry, it is often used as a key intermediate in drug synthesis. Due to the structure of thiophene and sulfonylamino, compounds are endowed with diverse biological activities. By modifying and modifying their structure, drugs with specific pharmacological activities can be developed, such as antibacterial, anti-inflammatory, anti-tumor and other drugs. For example, by chemically synthesizing this compound, linking it with other active groups may create new drug molecules targeting specific disease targets, which can help the pharmaceutical research and development process. < Br >
In the field of materials science, it may be able to participate in the preparation of functional materials. The thiophene structure endows the material with unique electrical and optical properties. For example, in the preparation of organic semiconductor materials, the introduction of this compound may improve the electrical conductivity and photoelectric conversion efficiency of the material, providing support for the development of organic electronic devices such as organic Light Emitting Diodes (OLEDs) and organic solar cells.
In the field of pesticides, there are also potential applications. With its cyano groups and other biologically active groups, new pesticides may be developed for pest control. Through rational design and synthesis, it can show high-efficiency inhibition and killing effects on specific pests or bacteria, and has a small impact on the environment, which is in line with the needs of green agriculture development. In addition, as an important intermediate in organic synthesis chemistry, this compound provides a foundation for the construction of more complex organic molecular structures, promotes the development of organic synthesis methodologies, and helps to synthesize more organic compounds with novel structures and unique functions. It is widely used in many fields.

The synthesis method of methyl 3-sulfonaminothiophene-2-carboxylic acid ester is an important matter for chemical preparation. Although the method of "Tiangong Kaiji" does not directly refer to this substance, the process concept contained in it may be useful for reference.
To synthesize this substance, one can first use thiophene as the starting material and introduce the desired functional group at a specific position of the thiophene ring through a series of substitution reactions. For example, the carboxyl group can be introduced at the 2-position of the thiophene ring first, which may be achieved by reacting with suitable carboxylic acid derivatives. This process requires precise control of reaction conditions, such as temperature, solvent, catalyst, etc. If the temperature is too high or side reactions occur frequently, if it is too low, the reaction rate will be slow.
Second, the sulfonyl aminocyanyl group is introduced at the 3-position. Sulfonyl chloride intermediates can be prepared first, and then they can be reacted with compounds containing cyanide and amino groups. This step also requires attention to the reactivity and selectivity to avoid unnecessary by-products.
Furthermore, the choice of solvent during the synthesis process is very critical. Suitable solvents not only promote the dissolution and mixing of reactants, but also have a significant impact on the reaction rate and selectivity. For example, some polar solvents may be beneficial to the ionic reaction, while non-polar solvents may be suitable for some nucleophilic substitution reactions.
In addition, the choice of catalysts cannot be ignored. Different reaction steps may require different catalysts to improve the reaction efficiency and yield.
Synthesis of methyl 3-sulfonaminocyanothiophene-2-carboxylate requires comprehensive consideration of raw materials, reaction conditions, solvents and catalysts, and careful design of reaction routes to achieve efficient and high-quality synthesis.

Methyl 3-sulfonaminothiophene-2-carboxylic acid ester is one of the organic compounds. Its physical and chemical properties are quite critical, and it is also of great significance for applications in chemical and related fields.
Looking at its physical properties, under normal temperature and pressure, this compound is mostly in a solid state, and its color may be white to white powder, which is easy to store and transport. Its melting point is also a significant physical property, but the exact melting point value often varies depending on the purity of the compound and the difference in measurement methods. Generally speaking, its melting point is in a specific temperature range, which is extremely important for controlling its processing and use conditions.
As for chemical properties, the sulfonylamino group, cyano group, thiophene ring and carboxylic acid ester group contained in this compound give it unique chemical reaction activity. Sulfonylamino group has certain nucleophilic and basic properties and can participate in many nucleophilic substitution reactions; cyano group has high activity and can undergo hydrolysis, addition and other reactions, and plays an important role in the construction of complex organic molecular structures. The presence of thiophene ring makes the compound have a certain aromaticity, which affects its electron cloud distribution and reaction selectivity. Carboxylic acid ester groups can undergo hydrolysis reactions under acidic or basic conditions to generate corresponding carboxylic acids and alcohols. This property is often used in organic synthesis for the transformation and modification of functional groups.
In addition, the solubility of methyl 3-sulfonaminocyanothiophene-2-carboxylate cannot be ignored. In common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., it exhibits a certain solubility, which helps it to disperse and participate in reactions in organic synthesis systems, and facilitates related chemical operations. In short, the physical and chemical properties of this compound are interrelated, which together determine its application and research value in the field of chemistry.

I have not heard the exact price of methyl 3-sulfonaminocyanothiophene-2-carboxylate in the market. However, looking at the prices of various things in the past, they often changed due to multiple reasons. The price of this compound depends on the price of the raw materials, the difficulty of the preparation method, and the situation of supply and demand. If the raw materials are rare, difficult to obtain, or complicated to make, and exquisite methods and various utensils are required, the price will be high. If there are many people seeking this thing, and there are few suppliers, the price will also be high. On the contrary, the raw materials are easy to produce, the production method is simple, and the supply exceeds the demand, the price may drop. If you want to know the exact price, you can visit the chemical material supplier and inquire about its quotation; or check the platform of chemical transactions to see the recent transaction price. In this way, you can know the approximate range of its market price.

Methyl 3-sulfonaminothiophene-2-carboxylic acid ester is an important compound in the field of organic synthesis. However, its manufacturer is not listed in "Tiangong Kaiwu", because it was written in the Ming Dynasty, when this chemical compound had not yet come out.
At present, many fine chemical companies are involved in the production of such compounds. Foreign countries such as BASF in Germany, as a global chemical giant, have excellent R & D and capacity, or have the ability to produce such fine chemicals. DuPont in the United States has also made fruitful achievements in the field of fine chemicals with its profound chemical heritage and cutting-edge technology, or produces methyl 3-sulfonaminothiophene-2-carboxylic acid esters.
In China, some companies that focus on fine chemical synthesis, such as Zhejiang Longsheng, have a significant position in the field of dye and intermediate production, with strong R & D and production strength, or are involved in the production of such compounds. There are also some listed companies that mainly focus on fine chemicals, such as Leap Tu shares, with their own technological accumulation and market expansion, or participate in the production of such products. In addition, some emerging high-tech fine chemical companies, with their innovative synthesis processes and technologies, may also be potential producers. However, the specific production situation needs to be further investigated before the chemical industry information, corporate product catalog, etc. can be determined.