What is the chemical structure of methyl 3- [ (methoxycarbonylmethyl) sulfamoyl] thiophene-2-carboxylate

The term "methyl+3-%5B%28methoxycarbonylmethyl%29sulfamoyl%5Dthiophene-2-carboxylate" refers to the name of organic chemistry. The name refers to a compound containing a thiophene ring. Its structure is as follows:

thiophene ring is a five-membered heterocyclic ring containing a sulfur atom and is aromatic. In the third position of the thiophene ring, there is a specific substituent. In this substituent, there is a sulfamoyl group, which is connected to the thiophene ring at one end and the methoxycarbonyl methyl (methoxycarbonylmethyl) at the other end. The so-called methoxycarbonyl methyl group is methoxycarbonyl at one end (-COOCH).

Furthermore, the second position of the thiophene ring is connected with a monocarboxylic acid methyl ester group (-COOCH 🥰), which means "carboxylate", indicating that it is an ester structure.

In summary, the structure of this compound is a thiophene ring with a carboxylic acid methyl ester group at the second position and a sulfonamide group containing methoxycarbonyl methyl at the third position. This structure endows the compound with specific physical and chemical properties, which may be used in organic synthesis, pharmaceutical chemistry and other fields or have specific uses.

What are the main uses of methyl 3- [ (methoxycarbonylmethyl) sulfamoyl] thiophene-2-carboxylate

Methyl 3- [ (methoxycarbonyl methyl) aminosulfonyl] thiophene-2-carboxylic acid ester, which is widely used. In the synthesis of medicine, it is often a key intermediate. Taking the creation of specific antimalarial drugs as an example, chemists skillfully connect them with various active groups through delicate reactions, resulting in compounds with high antimalarial activity. Due to the unique characteristics of malaria pathogens, the special structure of this intermediate can precisely fit with specific targets in the malaria parasite, thus hindering its growth and reproduction, laying the foundation for the development of antimalarial drugs.

In the field of pesticide research and development, this compound also plays an important role. The creation of many new insecticides relies on their unique chemical structure. Through a series of complex reactions, it is derived from substances with high selective poisoning ability to pests. The physiological structure and metabolic pathways of pests are different, and the insecticides made based on this intermediate can target specific physiological links of pests, interfere with the signal transduction of their nervous system, or destroy the normal function of their digestive system, effectively prevent and control crop diseases and insect pests, ensure the growth of crops, and increase agricultural yields.

In the field of materials science, methyl 3- [ (methoxycarbonyl methyl) sulfamyl] thiophene-2 -carboxylate has also emerged. In the preparation of special polymer materials, it can participate in the polymerization reaction as a functional monomer. By ingeniously designing the reaction conditions, it can copolymerize with other monomers to endow the polymer material with special properties. Or make the material have better thermal stability, which can still maintain its structure and properties in high temperature environments; or endow the material with unique optical properties, such as fluorescence properties, showing application potential in optical sensors and other fields.

What are the synthesis methods of methyl 3- [ (methoxycarbonylmethyl) sulfamoyl] thiophene-2-carboxylate

The preparation of methyl 3- [ (methoxycarbonylmethyl) sulfamoyl] thiophene-2-carboxylate is an important task in organic synthesis. The synthesis of this compound can be achieved through several paths.

One, or the thiophene derivative containing the sulfur heterocycle can be taken as the starting material. Introduce the appropriate substituent at the specific position of the thiophene first to construct the key intermediate. For example, introduce an active group at the 3-position of the thiophene, which needs to be able to react with the reagent containing the sulfonamide group and the methoxycarbonyl methyl group introduced later.

Second, prepare the reagent containing the sulfonamide group and the methoxycarbonyl methyl group. Usually, a suitable amine can be reacted with sulfonyl chloride to form a sulfonamide structure. After that, the methoxycarbonyl methyl group is attached to the sulfonamide through an appropriate reaction to obtain the key reaction fragment.

Third, the above-mentioned prepared thiophene derivative and the reagent containing sulfonamide group and methoxycarbonyl methyl are reacted under suitable reaction conditions. This reaction condition needs to be carefully selected. For example, the choice of reaction solvent is very important, and organic solvents such as dichloromethane, N, N-dimethylformamide can be selected to ensure good solubility of the reactants and smooth progress of the reaction. The reaction temperature also needs to be precisely controlled, or carried out at low temperature to room temperature to prevent side reactions from occurring. In addition, the addition of an appropriate amount of alkali, such as potassium carbonate, triethylamine, etc., can promote the reaction and move the reaction towards the direction of generating the target product.

After the reaction is completed, the product needs to be separated and purified. Column chromatography is often used, and a suitable eluent is selected to separate the target product from the reaction mixture to obtain pure methyl 3 - [ (methoxycarbonylmethyl) sulfamoyl] thiophene - 2 - carboxylate. In this way, after multiple steps of delicate operation, the desired compound can be obtained.

What are the physical and chemical properties of methyl 3- [ (methoxycarbonylmethyl) sulfamoyl] thiophene-2-carboxylate

Methyl 3- [ (methoxycarbonyl methyl) aminosulfonyl] thiophene-2-carboxylic acid ester, this is an organic compound. Its physical and chemical properties are quite important, and it is related to many uses and reaction characteristics of this compound.

Looking at its physical properties, it is mostly solid under normal conditions. Due to strong intermolecular forces, the molecules are arranged in an orderly manner. Melting point is a key indicator for determining purity and characteristics. The melting point of samples with different purity may vary, and the melting point of pure products is relatively fixed, which can be used as a purity criterion.

Solubility is also a key property. In organic solvents, such as common ethanol and acetone, because its molecular structure contains polar and non-polar parts, it can form interactions with organic solvent molecules, so it has a certain solubility. In water, due to the polarity of water molecules and the structural characteristics of the compound, solubility or limited.

As for chemical properties, the compound contains multiple functional groups, each with unique reactivity. Ester groups can be hydrolyzed, and react with water under acidic or basic conditions to form corresponding acids and alcohols. Aminosulfonyl groups have certain electrophilicity and can participate in nucleophilic substitution reactions to form new compounds. Thiophene rings are aromatic and can undergo electrophilic substitution reactions. Under specific conditions, such as suitable catalysts and reaction reagents, other functional groups can be introduced into thiophene rings.

In addition, the thermal stability of the compound also needs to be considered. Within a certain temperature range, the structure remains stable; if the temperature is too high, it may cause decomposition reactions and cause molecular structure changes. Many physical and chemical properties are interrelated, which affects its application in organic synthesis, materials science and other fields. In organic synthesis, use its reactive activity to prepare new compounds; in material preparation, choose appropriate processing methods and conditions according to its solubility and stability.

What is the market price of methyl 3- [ (methoxycarbonylmethyl) sulfamoyl] thiophene-2-carboxylate

The price of methyl 3 - [ (methoxycarbonyl methyl) aminosulfonyl] thiophene-2 -carboxylic acid ester is difficult to say in the market. These compounds may fluctuate in price due to different uses, difficulty in preparation, and market supply and demand.

If it is in the chemical raw material market, it may be a key material for organic synthesis, used to create various fine chemicals, pharmaceuticals, pesticides, etc. If the preparation of this product requires a fine process, high raw materials, and there are few market applicants, the price may be expensive. On the contrary, if the preparation is convenient and the supply exceeds the demand, the price should be easy.

If you want to know the exact market price, you must carefully check the chemical product trading platform, supplier quotations, or consult industry experts. The chemical market conditions are changing rapidly, and its price also shifts from time to time. It is difficult to determine its price in the market based on the name alone.