Methyl 3-amino-5-phenylthiophene-2-carboxylate

Methyl-3-amino-5-phenylthiophene-2-carboxylic acid esters have a wide range of uses. In the field of pharmaceutical chemistry, it is often a key intermediate for the creation of new drugs. Due to the special structure of thiophene and benzene ring, it is endowed with unique chemical and biological activities. It may be possible to modify and modify this compound to develop drugs with therapeutic effects on specific diseases, such as targeted drugs for certain inflammatory and tumor diseases.
In the field of materials science, it also has extraordinary performance. It may be used to prepare materials with special photoelectric properties. Due to the conjugated system in its structure, it may exhibit good conductivity and fluorescence, and can be applied to organic Light Emitting Diode (OLED), solar cells and other fields to improve the photoelectric conversion efficiency and stability of materials.
In the field of organic synthetic chemistry, it is an important synthetic building block. Chemists can use a variety of organic reactions, such as nucleophilic substitution, coupling reactions, etc., to build more complex and diverse organic molecular structures, expand the types and functions of organic compounds, and help the development of new organic materials, total synthesis of natural products and other research fields.

Methyl 3-amino-5-phenylthiophene-2-carboxylic acid esters have been synthesized for a long time. The first method is to take thiophene as a group and combine it with a benzene-containing reagent under specific reaction conditions to form the structure of 5-phenylthiophene. Subsequently, a carboxyl group is introduced into the structure, often by carboxylation, and after several steps of reaction, it is obtained at the second position. Then by esterification, the carboxyl group is reacted with methanol to form a carboxylic acid methyl ester structure.
Another method uses an amino-containing compound as the starting material and reacts with a suitable thiophene derivative. This reaction requires careful selection of reaction reagents and conditions, so that the amino group is cleverly connected to the third position of the thiophene ring. After that, follow similar steps to introduce phenyl and carboxyl groups and carry out esterification.
Furthermore, starting from raw materials containing thiophene, phenyl and carboxyl groups, according to a specific reaction sequence, the specific position can be protected to prevent unnecessary reactions. Then, under suitable catalyst and reaction environment, the introduction of amino groups is gradually realized, and the final product is methyl 3-amino-5-phenylthiophene-2-carboxylic acid ester. Each method requires careful study of reaction conditions, such as temperature, pressure, catalyst dosage, etc., to obtain satisfactory yield and purity.

Methyl-3-amino-5-phenylthiophene-2-carboxylic acid ester, this physical property belongs to the category of organic compounds. It has specific physical properties, and its appearance is often crystalline solid, with a white or microstrip color, depending on the purity.
When it comes to the melting point, after many experiments, it is about a certain temperature range. This value is an important physical sign of the substance, which can help to distinguish the purity and structural characteristics. Its boiling point also has a certain range. Under heating conditions, it will change from liquid to gaseous at a certain temperature.
In terms of solubility, it has a certain solubility in common organic solvents, such as ethanol, ether, etc. In ethanol, the solubility may change with increasing temperature. In water, due to its structural properties, the degree of solubility is very small, due to the hydrophobic groups in the molecule.
The density is a fixed value, reflecting its mass per unit volume. Compared with other similar structural compounds, its molecular compactness and atomic composition can be observed.
In addition, the stability of this substance to light and heat is also concerned. In the light environment, or due to factors such as intramolecular electron transition, certain chemical reactions occur to cause structural changes. When heated, before reaching the melting point, there may be signs of decomposition, and the decomposition temperature is also an important consideration parameter, which is related to its stability and application under different environmental conditions.

Methyl 3-amino-5-phenylthiophene-2-carboxylic acid ester, this is an organic compound. Its chemical properties are unique and interesting.
First talk about the amino group (-NH2O) it contains. This functional group gives the compound a certain alkalinity. Because nitrogen atoms have lone pairs of electrons and can accept protons, they can react with acids to generate corresponding salts. For example, in the case of hydrochloric acid, hydrochloric salts will be formed.
And ester groups (-COOCH 😉), it is active in nature. Under the condition of acid or base catalysis, hydrolysis is prone to occur. In an acidic environment, hydrolysis generates carboxylic acids and alcohols; in an alkaline environment, hydrolysis generates carboxylic acids and alcohols. Like in sodium hydroxide solution, it will hydrolyze to obtain sodium carboxylate and methanol.
The structure of the thiophene ring also has its own characteristics, which has certain aromaticity, making the compound relatively stable. However, the electron cloud distribution on the thiophene ring is uneven, and electrophilic substitution reactions are prone to occur at specific positions, such as halogenation, nitrification and other reactions, which can introduce other functional groups on the thiophene ring, thereby deriving a variety of compounds.
Furthermore, the presence of phenyl groups also affects the properties of the compound. Phenyl groups are large conjugated systems, which enhance the stability of molecules and also affect the physical properties of molecular solubility, melting point, boiling point, etc. Due to the hydrophobicity of phenyl groups, the solubility of the compound in organic solvents is better than that in water. The unique chemical properties of this compound make it widely used in the field of organic synthesis and can be used as a key intermediate to prepare various compounds with biological activity or special functions.

I look at this "Methyl 3-amino-5-phenylthiophene-2-carboxylate", which is the name of the chemical substance, translated into Chinese or "methyl 3-amino-5-phenylthiophene-2-carboxylate". However, the price range of this substance in the market is difficult to determine.
In the market, the price of chemical substances often varies for many reasons. First, the price of raw materials is the main factor. If the starting materials required for its preparation are scarce and expensive, the price of the finished product is also high; if the raw materials are easy to purchase and cheap, the price may be slightly lower. Second, the difficulty of preparation is related to the price. If the synthesis method is complicated, requires special equipment, harsh reaction conditions, or multi-step reaction and the yield is not high, the price will be high; if the preparation method is simple, the price may be close to the people. Third, the relationship between demand and supply also has an impact. If the product is in high demand in the chemical industry, medicine and other fields, but the supply is limited, the price will rise; if the demand is low and the supply is sufficient, the price may fall.
In addition, the prices sold by different suppliers in the market also vary. Large merchants may sell at competitive prices due to scale effects and good cost control; small merchants may sell at competitive prices due to high operating costs. And different purity, prices vary. For high purity, the preparation is difficult and the price is higher; for low purity, the price may be relatively low.
It is difficult to determine the price range of "3-amino-5-phenylthiophene-2-carboxylic acid methyl ester" due to unknown market conditions, raw material conditions, preparation processes and supply and demand. For details, consult chemical raw material suppliers, check professional chemical product price platforms, or refer to the price of congeneric products, combined with the above factors, to obtain a more accurate price range.