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What is the chemical structure of Methyl 3 - Amino - 5 - Phenyl - 2 - Thiophenecarboxylate
"Methyl+3+-+Amino+-+5+-+Phenyl+-+2+-+Thiophenecarboxylate" is the English name for organic compounds. According to chemical nomenclature, its structure can be analyzed.
"Methyl", showing methyl, is a group containing one carbon atom and three hydrogen atoms, often expressed as "-CH 🥰". "3 - Amino" means that the amino group (-NH ²) is connected to the third position of the main chain. "5 - Phenyl" indicates that the phenyl group (-C H) is in the fifth position of the main chain. "2 - Thiophenecarboxylate", where thiophenyl is a sulfur-containing five-membered heterocyclic ring, and "carboxylate" is a carboxylate group, connected to the second position of the thiophene ring.
In summary, the structure of this compound is as follows: the thiophene ring is used as the parent nucleus, and the carboxylic acid methyl ester group (-COOCH 🥰) is connected at the second position, the amino group is connected at the third position, and the phenyl group is connected at the fifth position. In this way, the chemical structure of this compound is outlined.
What are the main uses of Methyl 3 - Amino - 5 - Phenyl - 2 - Thiophenecarboxylate
Methyl-3-amino-5-phenyl-2-thiophenecarboxylate has a wide range of uses. In the field of medicine, it is often used as a key intermediate to help synthesize specific drugs. Due to its unique structure and specific biological activity, it can be chemically modified to produce therapeutic drugs for specific diseases, such as anti-cancer and anti-infection genera.
In materials science, it also has outstanding performance. It can be used to develop novel functional materials, such as organic photoelectric materials. Its molecular structural properties can affect the photoelectric properties of materials, such as fluorescence emission, charge transport, etc., providing the possibility for the preparation of high-performance photoelectric components, such as organic Light Emitting Diodes, solar cells, etc.
In the field of pesticides, it also plays an important role. It can be used as a raw material to synthesize high-efficiency and low-toxicity pesticides. By virtue of its mechanism of action against specific pests or pathogens, it can effectively control crop diseases and pests, ensure a bumper crop harvest, and have a small impact on the environment, which is in line with the needs of the current development of green agriculture.
In addition, in the path of scientific research and exploration, as an important object of organic synthesis research, chemists expand the knowledge boundary of organic chemistry by studying its reaction characteristics and structural transformation, promote the progress of organic synthesis methodologies, and lay a solid foundation for the synthesis of more complex and valuable compounds.
Methyl 3 - Amino - 5 - Phenyl - 2 - Thiophenecarboxylate
Methyl 3 - Amino - 5 - Phenyl - 2 - Thiophenecarboxylate (3 - amino - 5 - phenyl - 2 - thiophenecarboxylic acid methyl ester), Gu Zhifang's family wants to make this product, the following number can be selected.
First, thiophene derivatives are used as the base. First, take a suitable thiophene raw material and introduce phenyl at a specific position. This step can be used by electrophilic substitution. With a suitable aromatization reagent, such as halobenzene, assisted by a catalyst, react with thiophene. A catalyst or a metal salt, such as a palladium salt, is heated and stirred in a suitable solvent environment to make a coupling reaction between the two to obtain a 5-phenylthiophene derivative. Then, an amino group is introduced at the 3rd position of the thiophene ring. Nitro can be introduced by nitration reaction, a mixed acid of concentrated nitric acid and concentrated sulfuric acid, and a 5-phenylthiophene derivative at low temperature. Then the nitro group is converted to amino group by reduction method, such as iron powder, hydrochloric acid system, or catalytic hydrogenation method. Finally, esterification reaction is carried out at the 2nd position. The intermediate containing carboxyl group is taken, and the carboxyl group is heated and refluxed with methanol under the catalysis of concentrated sulfuric acid, so that the carboxyl group is esterified with methanol, and then Methyl 3 - Amino - 5 - Phenyl - 2 - Thiophenecarboxylate.
Second, start with phenyl derivatives. First, introduce the thiophene-containing group on the phenyl group. For example, in the presence of a suitable catalyst and base, halogenated phenyl and thiophene boric acid are coupled by Suzuki to form a compound containing phenyl and thiophene. Subsequent to the introduction of amino groups at the 3rd position of the thiophene ring in sequence, and the esterification reaction at the 2nd position is carried out. The steps are similar to the former.
Third, a strategy for constructing thiophene rings can also be used. With sulfur-containing, carbonyl-containing and amino-containing raw materials, thiophene rings are cyclized under specific reaction conditions. For example, with β-ketoate, sulfur source and aniline derivatives, thiophene rings are formed by cyclization reaction under acid catalysis, and the desired amino and phenyl groups are introduced into the rings. Finally, esterification modification is carried out as the case may be, and the target product can be obtained. All these methods need to be carefully selected according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the high or low yield, etc., to form the synthesis of this compound.
What are the physical properties of Methyl 3 - Amino - 5 - Phenyl - 2 - Thiophenecarboxylate
Methyl-3-amino-5-phenyl-2-thiophene carboxylic acid ester, this is an organic compound. Its physical properties are quite important, and it is related to its performance in many chemical processes and practical applications.
First of all, the appearance is usually white to light yellow crystalline powder, which is fine and uniform, giving a sense of purity. This morphology is conducive to uniform dispersion in many reaction systems, providing good starting conditions for the smooth development of the reaction.
Melting point is also a key physical property. After experimental determination, its melting point is in a specific temperature range, which is of great significance for identifying the compound and controlling its state change during heating. When the temperature gradually rises near the melting point, the compound slowly transitions from a solid state to a liquid state. This phase transition process has a profound impact on the handling and processing of materials in the fields of organic synthesis and material preparation.
The solubility cannot be ignored either. In common organic solvents, such as ethanol and dichloromethane, it exhibits a certain solubility. In ethanol, it can be dissolved to form a uniform solution at moderate temperature and stirring conditions, which makes it convenient to participate in various solution-phase chemical reactions. At the same time, in pharmaceutical preparations, it contributes to the uniform dispersion and release of active ingredients. However, the poor solubility in water is closely related to the presence of hydrophobic groups in the molecular structure of the compound, which hinders the interaction with water molecules and limits its application in aqueous systems.
In addition, the compound has a certain density. Although the specific value will vary slightly due to factors such as purity, it is relatively stable within a specific range. This property of density is crucial in processes involving material measurement and mixing. Only by accurately knowing the density can we ensure that the proportion of each material in the production or experimental process is accurate, thereby ensuring product quality and reaction effect.
Methyl 3 - Amino - 5 - Phenyl - 2 - What is the market outlook for Thiophenecarboxylate
Guanfu methyl-3-amino-5-phenyl-2-thiophene carboxylic acid ester, in the market prospect, should be determined by many factors.
First look at its field, this compound is of great significance in the field of medicinal chemistry and organic synthesis. In the field of medicine, it may be a key intermediate for the creation of new drugs. In today's world, the demand for specific drugs is increasing day by day, new diseases are frequent, and old diseases also need better treatments. If this compound can emerge in drug research and development and become an important link in the synthesis of a specific drug, its market prospect will be limitless.
Furthermore, the development of organic synthesis chemistry also brings opportunities for it. Organic synthesis aims to create novel molecular structures with specific functions, and the unique structure of this compound may be favored by synthetic chemists as a cornerstone for the construction of more complex and special properties of organic molecules. With the improvement of organic synthesis technology, the demand for this compound may gradually increase.
However, it also needs to be considered and the challenges it faces. If the process of synthesizing this compound is complicated and expensive, it will hinder its large-scale production and marketing activities. And the market competition is quite fierce. If there is a similar effect and cheaper alternative, it will also endanger the market share of this compound.
In summary, the market prospect of methyl-3-amino-5-phenyl-2-thiophene carboxylic acid ester, although there are opportunities due to the demand in the field of medicine and organic synthesis, is also constrained by factors such as synthesis cost and competition. Only by overcoming synthesis problems, reducing costs, and highlighting its unique advantages can it occupy a favorable position in the market.