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What are the main uses of ethyl 5- [bis (2-ethoxy-2-oxo-ethyl) amino] -4-cyano-3- (2-ethoxy-2-oxo-ethyl) thiophene-2-carboxylate
ethyl+5-%5Bbis%282-ethoxy-2-oxo-ethyl%29amino%5D-4-cyano-3-%282-ethoxy-2-oxo-ethyl%29thiophene-2-carboxylate, this is the name of an organic compound. It has many applications in the field of organic synthesis.
Looking at the structure of this compound, it contains many specific functional groups, such as ethoxycarbonyl, cyano, thiophene ring, etc. It is often used as a key intermediate in organic synthesis. Taking the ethoxycarbonyl group contained in its structure as an example, this functional group is active and can participate in many chemical reactions, such as transesterification reaction, hydrolysis reaction, etc. Through transesterification, ester groups of different structures can be introduced to enrich the variety of compounds; after hydrolysis, corresponding carboxylic acids can be obtained, which lays the foundation for the subsequent construction of more complex molecular structures. The
cyanyl group is also of great significance. It can be converted into other functional groups through many reactions, such as amide groups, carboxyl groups, etc., to expand the chemical properties and application scope of compounds. The thiophene ring endows the compound with unique electronic properties and stability, and is often a key structural unit when synthesizing materials with specific optoelectronic properties.
In the field of pharmaceutical chemistry, this compound is used as a starting material. After rational modification and transformation, it may be able to construct molecules with biological activity, and it is expected to be developed into new drugs. In the field of materials science, due to its specific structure, it may be used to prepare organic materials with special properties, such as optoelectronic materials, polymer materials, etc. In the art of organic synthesis, this compound is widely used as an intermediate due to its unique structure, paving the way for the creation of various functional compounds, and has potential value in drug research and development, material preparation, and other fields.
What are the synthesis methods of ethyl 5- [bis (2-ethoxy-2-oxo-ethyl) amino] -4-cyano-3- (2-ethoxy-2-oxo-ethyl) thiophene-2-carboxylate
To prepare ethyl + 5 - [bis (2 - ethoxy - 2 - oxo - ethyl) amino] - 4 - cyano - 3 - (2 - ethoxy - 2 - oxo - ethyl) thiophene - 2 - carboxylate, there are many methods, which can be selected according to factors such as required raw materials, equipment and cost.
First, it can be started by a compound containing a thiophene structure. First, take a thiophene derivative with a suitable substituent, make it react with a cyanyl-containing reagent under suitable conditions, and introduce a cyano group. If a base is used as a catalyst, the reaction is heated in an organic solvent to promote the cyanosubstituted thiophene ring atom or group at a specific position.
Then, the resulting product is condensed with a compound containing an ethoxy carbonyl group. This step may require the assistance of a condensing agent, such as dicyclohexyl carbodiimide (DCC), at mild temperatures, so that the two condensate to construct the desired ester group and amide structure.
Furthermore, you can try to modify the sulfur atom on the thiophene ring. Or choose an appropriate halogenated ethoxy carbonyl compound, react with the sulfur atom of the thiophene ring under metal catalyst or basic conditions, and introduce the (2-ethoxy-2-oxo-ethyl) group.
During the reaction process, the reaction temperature, time and the proportion of the reactants need to be carefully controlled. If the temperature is too high or the side reactions are clustered, and if it is too low, the reaction rate will be delayed. The proportion of the reactants is also critical. If the ratio is improper, or the product is impure, the yield will be affected.
After each step of the reaction, suitable separation and purification methods, such as column chromatography and recrystallization, are required to obtain the pure product. After multi-step reaction and purification, ethyl + 5 - [bis (2 - ethoxy - 2 - oxo - ethyl) amino] - 4 - cyano - 3 - (2 - ethoxy - 2 - oxo - ethyl) thiophene - 2 - carboxylate was obtained.
What are the physicochemical properties of ethyl 5- [bis (2-ethoxy-2-oxo-ethyl) amino] -4-cyano-3- (2-ethoxy-2-oxo-ethyl) thiophene-2-carboxylate
This is ethyl 5- [bis (2-ethoxy-2-oxyethyl) amino] -4-cyano-3- (2-ethoxy-2-oxyethyl) thiophene-2-carboxylic acid ester. Looking at this compound, its physical and chemical properties are quite elegant.
In terms of physical properties, its appearance may be solid, but the exact state depends on the specific synthesis and environmental conditions. Its melting point and boiling point are key physical parameters. The melting point reflects the temperature at which it transitions from solid to liquid, and the boiling point is related to the conditions for liquid to gas. The two are influenced by intermolecular forces. There are many polar groups in the molecule of the compound, such as cyanyl groups, ester groups, and groups containing nitrogen and oxygen, which increase the intermolecular forces, or make the melting point and boiling point at a higher level.
In terms of solubility, because the molecule contains many polar parts, it may have a certain solubility in polar solvents such as alcohols and ketones. In non-polar solvents such as alkanes, the solubility may be very small. Due to the principle of "similar compatibility", polar molecules are more likely to interact with polar solvents.
In terms of chemical properties, cyanyl groups can participate in many reactions, such as hydrolysis reactions. Under acidic or basic conditions, cyanyl groups can be converted into carboxyl groups or amide groups. The ester group is also active and can undergo hydrolysis reaction. It is hydrolyzed in acidic medium to form carboxylic acids and alcohols, and hydrolyzed more thoroughly under alkaline conditions to form carboxylic salts and alcohols. In addition, although the thiophene ring is relatively stable, it may also react under specific conditions, such as the action of strong oxidants. The electron cloud distribution on the ring is affected by the substituent group, or the reactive activity is slightly different from that of the thiophene itself. Groups containing nitrogen and oxygen atoms in the molecule can be used as nucleophiles or electrophilic reagents to participate in the reaction, and react with suitable substrates such as substitution and addition. In short, due to the diverse groups in the structure, this compound has rich physical and chemical properties and reactive activities, and may have potential uses in organic synthesis and other fields.
Ethyl 5- [bis (2-ethoxy-2-oxo-ethyl) amino] -4-cyano-3- (2-ethoxy-2-oxo-ethyl) thiophene-2-carboxylate what is the price in the market
I look at this question and ask ethyl + 5 - [bis (2 - ethoxy - 2 - oxo - ethyl) amino] - 4 - cyano - 3 - (2 - ethoxy - 2 - oxo - ethyl) thiophene - 2 - carboxylate at the market price. However, this is a fine chemical, and its price is not constant and is affected by many factors.
First, the quantity is small. If the quantity is large, the supplier may give a discount to promote the transaction.
Second, the quality is good or bad. Those with high quality, the production process may be more complicated, the raw materials may be more sophisticated, and the price is also high. Those with slightly inferior quality, the price may be slightly lower, but it may affect the effectiveness of use.
Third, the source is different. Different manufacturers, due to differences in cost, technology, and market positioning, have different pricing. Well-known large factories, or due to the superiority of brands and after-sales, have higher prices; emerging small factories, or to expand the market, the price may be close to the people.
Fourth, the supply and demand of the city. If there are many applicants and few suppliers, the price may rise; if supply exceeds demand, the price may decline.
And the market fluctuates, raw material prices, policies and regulations, transportation costs, etc., can all change their prices. Therefore, to know the exact price, you need to consult chemical raw material suppliers, distributors, or check in detail on professional chemical trading platforms to get a more accurate price.
What are the application fields of ethyl 5- [bis (2-ethoxy-2-oxo-ethyl) amino] -4-cyano-3- (2-ethoxy-2-oxo-ethyl) thiophene-2-carboxylate
Ethyl+5-%5Bbis%282-ethoxy-2-oxo-ethyl%29amino%5D-4-cyano-3-%282-ethoxy-2-oxo-ethyl%29thiophene-2-carboxylate is an organic compound with a specific chemical structure and properties. This compound has a wide range of application fields and can be used as a potential drug intermediate in the field of medicinal chemistry. Because the structure contains a variety of active functional groups, or it can be chemically modified to synthesize molecules with specific pharmacological activities for the treatment and research of diseases, such as the development of anti-cancer drugs. By modifying its structure or designing compounds that can target cancer cells.
In the field of materials science, or can be used to prepare materials with special functions. Because of its unique chemical structure, it may endow materials with special optical, electrical or mechanical properties. For example, the integration of polymer materials through specific processes may improve the stability and processability of materials, and be applied to the preparation of high-performance plastics to enhance the durability and functionality of materials.
In the field of organic synthetic chemistry, this compound can be used as a key intermediate to participate in the construction of complex organic molecules. With its rich reaction check points, it can expand the carbon chain and introduce various functional groups through various organic reactions, such as nucleophilic substitution and condensation reactions, to help synthesize organic compounds with complex structures and special functions, providing new ways and methods for the development of organic synthetic chemistry.