What is the chemical structure of ethyl 4,5-dimethyl-2- ({[1- (phenylsulfonyl) cyclopropyl] carbonyl} amino) thiophene-3-carboxylate

This is the description of the chemical substance, which is called "ethyl 4,5-dimethyl-2 - ({[1 - (benzenesulfonyl) cyclopropyl] carbonyl} amino) thiophene-3-carboxylic acid ester". To clarify its chemical structure, it can be disassembled and analyzed according to this name.

"ethyl", is an ethyl group, which is a common group in organic compounds, with a structure of -C ² H, which is a substituent attached to the molecular body.

"4,5-Dimethyl", indicating that there is a methyl group (-CH 🥰) attached to the 4th and 5th positions of the thiophene ring. The thiophene ring is a sulfur-containing five-membered heterocycle with a structure of: a five-membered ring in which one carbon atom is replaced by a sulfur atom.

"2- ({[1- (benzenesulfonyl) cyclopropyl] carbonyl} amino) ", this part is more complex. "[ 1 - (benzenesulfonyl) cyclopropyl] ", the cyclopropyl group is a ternary carbon ring, and the benzenesulfonyl group is connected to the 1 position of the cyclopropyl group, and the benzenesulfonyl group structure is -SO ² -phenyl;" carbonyl "is -C = O; this whole is connected to the amino group through the carbonyl group, and then connected to the 2 positions of the thiophene ring.

" thiophene-3-carboxylic acid ester "means that the 3 positions of the thiophene ring are connected with the carboxylic acid ester structure. Combined with the previous" ethyl ", it can be seen that it is an ester formed by carboxylic acid and ethanol, that is, -COO

In summary, the chemical structure of this compound is composed of ethyl and dimethyl substituted thiophene rings, and complex side chains containing benzenesulfonyl cyclopropyl groups through specific connection methods. After this analysis, the structure is clear and distinguishable.

What are the physical properties of ethyl 4,5-dimethyl-2- ({[1- (phenylsulfonyl) cyclopropyl] carbonyl} amino) thiophene-3-carboxylate

Ethyl 4,5-dimethyl-2 - ({[1 - (benzenesulfonyl) cyclopropyl] carbonyl} amino) thiophene-3-carboxylic acid ester, this is an organic compound. Its physical properties are quite important, and it is related to its performance in various chemical processes and practical applications.

First, the appearance is usually white to light yellow crystalline powder. This appearance characteristic is related to the arrangement and crystallization habits of the molecules. Intermolecular interactions, such as van der Waals forces, hydrogen bonds, etc., cause it to form a specific crystalline structure, resulting in this appearance.

Melting point is also a key physical property. The melting point of the compound is determined by experiments to be within a certain temperature range. The melting point depends on the strength of the intermolecular forces. There are functional groups such as benzenesulfonyl, carbonyl, and amino in the molecule of the compound. The interactions formed between these functional groups, especially the hydrogen bond and the dipole-dipole interaction, strengthen the binding force between molecules, so a higher temperature is required to break the lattice and realize the transition from solid to liquid.

In terms of solubility, it has a certain solubility in organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. This is because the polarity of these organic solvents matches the polarity of the compound molecule, and follows the principle of "similar miscibility". The benzene ring, cyclopropyl group and other non-polar parts of the molecule interact with the non-polar region of the organic solvent, while the polar carbonyl group, amino group, sulfonyl group, etc. interact with the polar part of the organic solvent, so that it can be dissolved. However, the solubility in water is very small. Due to the strong polarity of water molecules, the interaction with the molecules of the compound is difficult to effectively overcome the intramolecular and intermolecular forces, so it is not easy to dissolve.

In addition, the density of the compound is in a certain value range. The density is closely related to the mass of the molecule and the molecular accumulation. Its molecular structure contains multiple atoms, which are relatively large in mass, and the spatial arrangement of the molecules determines the mass in its unit volume, which in turn presents a specific density.

The above physical properties are of great significance for the study of the synthesis, purification, stability of this compound and its application in pharmaceutical chemistry, materials science and other fields.

What is the synthesis method of ethyl 4,5-dimethyl-2- ({[1- (phenylsulfonyl) cyclopropyl] carbonyl} amino) thiophene-3-carboxylate

To prepare ethyl 4, 5 - dimethyl - 2 - ({[1 - (phenylsulfonyl) cyclopropyl] carbonyl} amino) thiophene - 3 - carboxylate, the following ancient method can be used.

First take the appropriate starting material, take 4,5 - dimethylthiophene - 3 - carboxylic acid ethyl ester as the base for constructing the carbon frame of the target molecule. React it with the active intermediate containing {[1 - (phenylsulfonyl) cyclopropyl] carbonyl} amino group. This active intermediate needs to be prepared in advance, and benzenesulfonyl cyclopropane can be taken as the starting material. After carbonylation, a carbonyl group is introduced into the cyclopropane at a specific position, and then reacts with ammonia or ammonia derivatives to form an amino-containing structure containing {[1 - (benzenesulfonyl) cyclopropyl] carbonyl}.

When the active intermediate is ready, in a suitable reaction medium, such as an anhydrous organic solvent, such as dichloromethane, N, N-dimethylformamide, etc., 4,5-dimethylthiophene-3-carboxylic acid ethyl ester is mixed with it. The reaction system needs to be controlled at an appropriate temperature, depending on the activity of the reagent used and the difficulty of the reaction, or at a low temperature, such as about 0 ° C, to facilitate selective reaction; or at room temperature, so that the reaction can proceed smoothly; or properly heated, to 40-60 ° C, to speed up the reaction rate. In this process, an appropriate amount of catalysts can be added, such as organic bases, such as triethylamine, pyridine, etc., to promote the reaction, catalyzing the condensation reaction between the amino group of the active intermediate and the carboxyl derivative of 4,5-dimethylthiophene-3-carboxylate to form an amide bond of the target molecule.

After the reaction is completed, it is post-processed. The reaction mixture was extracted with an organic solvent, the organic phase was collected, and then washed with water and dried to remove impurities. Subsequently, the product was purified by column chromatography or recrystallization to obtain pure ethyl 4,5 - dimethyl - 2 - ({[1- (phenylsulfonyl) cyclopropyl] carbonyl} amino) thiophene - 3 - carboxylate.

What are the application fields of ethyl 4,5-dimethyl-2- ({[1- (phenylsulfonyl) cyclopropyl] carbonyl} amino) thiophene-3-carboxylate

Ethyl 4,5-dimethyl-2 - ({[1 - (benzenesulfonyl) cyclopropyl] carbonyl} amino) thiophene-3-carboxylic acid ester, this compound has important uses in medicine, agriculture and other fields.

In the field of medicine, it may be a key intermediate in drug synthesis. By means of organic synthesis, through specific reaction steps, it can be combined with other molecular fragments to create new compounds with specific pharmacological activities. Because its structure contains special functional groups, it can precisely fit with targets in organisms or intervene in specific biochemical reaction processes, so as to exert the effect of treating diseases. For specific disease-related enzymes or receptors, such compounds may exhibit inhibitory or activating effects, thus providing direction for the development of new drugs.

In the field of agriculture, it may be used as a basic raw material for the creation of pesticides. Due to the uniqueness of the molecular structure, or the special ability to inhibit or kill certain pests and pathogens. With modern pesticide research and development technology, it can be developed into high-efficiency, low-toxicity and environmentally friendly pesticide products to protect crops from pests and diseases, and improve crop yield and quality.

In addition, in the field of chemical research, the unique structure of this compound also provides a good substrate for organic synthesis methodology research. Scientists can explore new reaction paths and methods by studying the various chemical reactions they participate in, expand the boundaries of organic synthetic chemistry, and lay the foundation for the synthesis of more complex compounds.

What is the market outlook for ethyl 4,5-dimethyl-2- ({[1- (phenylsulfonyl) cyclopropyl] carbonyl} amino) thiophene-3-carboxylate

There are ethyl 4,5-dimethyl-2- ({[1 - (benzenesulfonyl) cyclopropyl] carbonyl} amino) thiophene-3-carboxylic acid ester, which is an organic compound. Looking at its market prospects, it needs to be discussed from a variety of factors.

First talk about its application field, this compound may emerge in the field of pharmaceutical research and development. When creating new drugs, its unique molecular structure may endow drugs with specific biological activities, which can play a role in specific disease targets, such as in the development of anti-tumor, anti-infective drugs, or as a key intermediate, helping to synthesize highly active and selective drug molecules. If the application can be expanded in this field, its market demand is expected to surge.

In the chemical industry, in the synthesis of fine chemicals, or because of its special chemical properties, it is used as an important building block for the construction of complex organic molecules, providing the possibility for the synthesis of high value-added fine chemicals. Chemical companies may increase their demand with the development of the fine chemical industry.

Looking at its market prospects, there are also challenges. The process of synthesizing this compound may be complex and costly. If the synthesis route cannot be optimized to reduce costs, it may be at a disadvantage in the market competition. Furthermore, the road of new drug research and development is long and risky. If the drug research and development based on this compound is frustrated, its market demand will also be suppressed.

In summary, the market prospect of ethyl 4,5-dimethyl-2- ({[1 - (benzenesulfonyl) cyclopropyl] carbonyl} amino) thiophene-3-carboxylate has both opportunities and challenges. If we can break through the bottleneck of the synthesis process and successfully expand the application in the field of medicine and chemical industry, we will be able to find a place in the market, and the future may be bright; on the contrary, if we are trapped in cost and R & D risks, the market road may be full of thorns.