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What is the chemical structure of ETHYL 2-AMINO-4-METHYL-5- (4-NITRO-PHENYL) -THIOPHENE-3-CARBOXYLATE
ETHYL 2-AMINO-4-METHYL-5- (4-NITRO-PHENYL) -THIOPHENE-3-CARBOXYLATE, according to its name, it can be inferred as follows:
This compound is mainly THIOPHENE, thiophene is a five-membered compound, and contains a sulfur atom. In the third position of thiophene, there is an ethyl monocarboxylate group (ETHYL -CARBOXYLATE), which is an ester group formed from carboxyl ethanol, that is, -COOCH
The fourth position of thiophene has a methyl group (METHYL), that is, a -CH group. The fifth position of thiophene has a 4-nitrophenyl group (4-NITRO-PHENYL), and the phenyl and benzene groups remove an atomic group. The fourth position of thiophene (related to the carbon group of thiophene) has a nitro group (-NO.
In addition, the second position of thiophene has an amino group (AMINO), that is, -NH.
of, ETHYL 2-AMINO-4-METHYL-5- (4-NITRO-PHENYL) of the -THIOPHENE-3-CARBOXYLATE by the thiophene core, the surrounding is connected with an amino group, methyl, nitrophenyl and carboxylic acid ethyl ester group and the like, each group according to its name shown in the position of on thiophene, this has a specific compound.
What are the main uses of ETHYL 2-AMINO-4-METHYL-5- (4-NITRO-PHENYL) -THIOPHENE-3-CARBOXYLATE
ETHYL 2 - AMINO - 4 - METHYL - 5 - (4 - NITRO - PHENYL) - THIOPHENE - 3 - CARBOXYLATE, that is, 2 - amino - 4 - methyl - 5 - (4 - nitro - phenyl) - thiophene - 3 - ethyl carboxylate, this substance is quite versatile.
In the field of pharmaceutical chemistry, it is often a key intermediate in the synthesis of many specific drugs. Through delicate chemical modifications and reactions, compounds with unique pharmacological activities can be derived, or they can act on specific disease targets, paving the way for innovative drug research and development. For example, in the development of anti-tumor drugs, this is used as a starting material to build complex molecular structures through multi-step reactions, and it is expected to obtain anti-cancer drugs with high selectivity and strong activity.
In the field of materials science, it can participate in the preparation of functional polymer materials. With its own unique chemical structure, it copolymerizes with other monomers or modifies the surface of the material, giving the material special properties such as photoelectric properties, thermal stability, chemical stability, etc. For example, introducing it into polymer systems is expected to improve the absorption and emission ability of materials to specific wavelengths of light, and be applied to optoelectronic devices, such as organic Light Emitting Diodes, solar cells, etc.
In the field of organic synthetic chemistry, as an important building block for organic synthesis, it provides a foundation for the construction of complex organic molecules. Its various reaction check points can participate in various reactions such as nucleophilic substitution, electrophilic substitution, and cyclization. Organic chemists use this to construct novel and complex organic compounds, promoting the continuous progress and development of organic synthetic chemistry, and laying the foundation for the discovery of more new substances with potential application value.
What is the synthesis method of ETHYL 2-AMINO-4-METHYL-5- (4-NITRO-PHENYL) -THIOPHENE-3-CARBOXYLATE?
ETHYL 2 - AMINO - 4 - METHYL - 5 - (4 - NITRO - PHENYL) - THIOPHENE - 3 - CARBOXYLATE, that is, 2 - amino - 4 - methyl - 5 - (4 - nitro - phenyl) - thiophene - 3 - ethyl carboxylate, the synthesis method is quite complicated, and it needs to follow certain steps and procedures.
First, when selecting a suitable starting material. 4-Methyl-5- (4-nitro-phenyl) -thiophene-3-carboxylic acid is often used as the starting material, which can be obtained from the corresponding thiophene derivatives through nitration and other necessary reactions. Then, 4-methyl-5- (4-nitro-phenyl) -thiophene-3-carboxylic acid and ethanol are esterified under acid-catalyzed conditions. In this process, the acid can be selected from common strong acids such as sulfuric acid, and the reaction between acid and alcohol can be promoted at appropriate temperature and time to form corresponding esters. < Br >
When the reaction is completed, the reaction conditions need to be carefully regulated. The temperature should not be too high, otherwise side reactions may occur, affecting the purity and yield of the product. Generally speaking, the reaction temperature can be controlled in a moderate range, such as between 60 and 80 degrees Celsius. The reaction time also needs to be properly controlled, usually lasting for several hours. The reaction process needs to be monitored by means of thin-layer chromatography. The reaction can only be terminated when the basic reaction of the raw materials is complete.
After the reaction is completed, the product needs to be separated and purified. Column chromatography is often used, and a suitable eluent is selected to effectively separate the product from impurities. Or it can be combined with methods such as recrystallization to further improve the purity of the product.
This synthesis method, although many details need to be paid attention to, can obtain a higher purity of ETHYL 2-AMINO-4-METHYL-5- (4-nitro-phenyl) -thiophene-3-carboxylic acid ethyl ester product by following the correct steps and conditions.
What are the physical properties of ETHYL 2-AMINO-4-METHYL-5- (4-NITRO-PHENYL) -THIOPHENE-3-CARBOXYLATE
ETHYL 2 - AMINO - 4 - METHYL - 5 - (4 - NITRO - PHENYL) - THIOPHENE - 3 - CARBOXYLATE is an organic compound. Looking at its structure, this compound contains a thiophene ring connected with an amino group, methyl group, nitrophenyl group and carboxyethyl ester group. These groups endow the compound with unique physical properties.
In terms of solubility, due to the presence of polar amino groups, carboxyethyl ester groups, and non-polar thiophene rings and nitrophenyl groups in the molecule, it has a certain solubility in polar organic solvents such as ethanol and acetone, but its solubility in water may be limited. This is because water is a strong polar solvent, and the overall polarity of the compound is not very high, and the force of the interaction between the polar part and the water molecule is difficult to resist the hindrance of the solubility of the non-polar part.
In terms of melting boiling point, there is a van der Waals force between molecules, and the amino group can form hydrogen bonds. These interactions enhance the binding force between molecules, so the melting boiling point should not be low. High energy is required to overcome the intermolecular force, so that it can change from solid state to liquid state, or from liquid state to gas state.
The stability of this compound is also worthy of attention. The nitro group of nitrophenyl group has strong electron absorption, which can affect the electron cloud density of thiophene ring and change the reactivity of thiophene ring. However, the electron cloud distribution is regulated to a certain extent by the action of amino groups. In general, under normal conditions, if there is no special reagent or external conditions to stimulate, the compound has certain stability. However, in the case of strong oxidizing agents, reducing agents or specific acid-base conditions, some groups in its structure may react, causing the stability of the compound to be affected.
In addition, its appearance may be solid, and it tends to be closely arranged into a solid state due to strong intermolecular forces. The color may be slightly presented due to the presence of nitrophenyl groups. The conjugated structure of nitro groups can absorb specific wavelengths of light, or give the appearance of the compound a yellowish color.
What is the market outlook for ETHYL 2-AMINO-4-METHYL-5- (4-NITRO-PHENYL) -THIOPHENE-3-CARBOXYLATE?
ETHYL 2 - AMINO - 4 - METHYL - 5 - (4 - NITRO - PHENYL) - THIOPHENE - 3 - CARBOXYLATE, Chinese name or 2 - amino - 4 - methyl - 5 - (4 - nitro - phenyl) - thiophene - 3 - ethyl carboxylate. The market prospect of this product is related to various factors, and listen to me in detail.
In the field of pharmaceutical and chemical industry, it may have potential uses. Nowadays, in pharmaceutical research and development, compounds with specific structures and activities are often looked for to make new drugs. The unique structure of this compound may make it exhibit pharmacological activity, such as antibacterial, anti-inflammatory, anti-tumor, etc. If its activity is confirmed by in-depth research and can be prepared in large quantities through effective synthesis routes, it will definitely attract the attention of pharmaceutical companies and have broad market prospects. As in the past, many new drug research and development began with such characteristic compounds, and then after a series of research and development, it became a best-selling drug.
In the field of materials science, there are also opportunities for development. Materials research and development continue to pursue new functional materials. This compound may play a role in the modification of optoelectronic materials and polymer materials due to its specific functional groups. If new materials based on this compound can be developed to meet the market demand for high-performance materials, its market space should not be underestimated.
However, its market development also faces challenges. In terms of synthesis, complex structures or synthesis are difficult and costly, which affects large-scale production. And the market competition is fierce, and it needs to compete with other similar compounds in the application field. If it cannot highlight its advantages in performance, cost and other aspects, it may be difficult to occupy a place in the market.
Overall, ETHYL 2 - AMINO - 4 - METHYL - 5 - (4 - NITRO - PHENYL) - THIOPHENE - 3 - CARBOXYLATE has addressable market opportunities, but it needs to overcome the problems of synthesis and competition, and it is expected to emerge in the market and open up a world.