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What is the chemical structure of ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate?
Eh, this "ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate" is the English name of an organic compound. To clarify its chemical structure, it is necessary to analyze it according to the naming rules.
"ethyl", ethyl is also an alkyl group containing two carbon atoms, expressed in -C ² H, often connected to the molecular main chain. "2- (acetylamino) ", "acetyl" is an acetyl group, "amino" is an amino group, and the combination is an acetylamino group, and connected to the main chain at position 2. The structure of "acetylamino" is -NHCOCH.
"4- (pyridin-3-yl) ", "pyridin" is a pyridine, the pyridine ring is a nitrogen-containing hexaadic ring, "3-yl" shows that the pyridine ring is connected to the main chain at position 4, the structure of the pyridine ring is, and the connection to the main chain is at position 3 on the ring.
"thiophene" is a thiophene, which is a sulfur-containing five-membered heterocycle and is the core part of the molecular mainchain. thiophene ring structure is.
"3-carboxylate", "carboxylate" is a carboxylic acid ester group, connected to the thiophene ring at position 3, and "ethyl" is connected to form the carboxylic acid ethyl ester structure-COOCH -2 CH.
In summary, the chemical structure core of this compound is a thiophene ring, with acetamide-NHCOCH at position 2, pyridine-3-yl at position 4, and carboxylate-COOCH at position 3. Its specific structure can be depicted by text description to illustrate the appearance of its atomic connection, so that scholars can glimpse the chemical structure of this organic compound.
What are the main uses of ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate?
Ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate is an important compound in the field of organic synthesis. It has a wide range of main uses and is often used as a key intermediate in the field of medicinal chemistry to prepare drug molecules with specific biological activities. Due to the unique structure of the compound, it can be modified by various chemical reactions to impart specific pharmacological properties to the resulting drug, such as acting on specific targets to treat related diseases.
It also has its uses in the field of materials science. Its structure imparts special physical and chemical properties, or it can be used to synthesize materials with special properties, such as optoelectronic materials. The specific part of its molecular structure may participate in the electron transport process inside the material, which in turn affects the optical and electrical properties of the material, making the material suitable for the fabrication of devices such as organic Light Emitting Diodes.
In addition, in the study of organic synthesis methodologies, ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate is also an important research object. Chemists often use it as a substrate to explore new chemical reaction paths and reaction conditions, so as to develop more efficient and green organic synthesis methods, and promote the progress and development of organic synthesis chemistry. In short, this compound is of great significance in many scientific research fields and has a significant role in promoting scientific research and related industrial development.
What are the synthesis methods of ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate?
To obtain the synthesis method of ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate, the following method can be used.
First take the appropriate starting material, and use the compound containing pyridyl and thiophene as the base. For example, take the pyridine derivative and the thiophene derivative with the suitable substituent as the starting material. The pyridine derivative is condensed with the thiophene derivative under suitable reaction conditions. This reaction may require the assistance of specific catalysts, such as some metal catalysts, to promote the bonding of the two.
After the condensation, the introduction step of the acetamide group is carried out. A suitable acetylation reagent can be selected, and in a suitable reaction environment, it can interact with the condensation product to acetylate the amino group, so as to obtain the part containing the acetamide group.
And the step of carboxyl ethylation is also critical. Appropriate alcohols can be selected, and under catalytic conditions, they can react with the intermediate containing carboxyl groups to achieve ethylation, and finally obtain the target product ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate. Each step of the reaction requires attention to the precise control of the reaction conditions, such as temperature, reaction time, ratio of reactants, etc., in order to obtain a higher yield and purity product. After the reaction, it needs to be separated and purified to obtain a purified target compound.
What are the physical and chemical properties of ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate?
Ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate is an organic compound with unique physical and chemical properties. It is a white to light yellow crystalline powder and is stable at room temperature and pressure. The melting point of this substance is between 100 and 105 ° C. The melting point characteristic makes it undergo phase transition at a specific temperature environment, which has a great impact on its storage and processing.
In terms of solubility, it is slightly soluble in water, but easily soluble in common organic solvents such as dichloromethane, chloroform and ethanol. This solubility property is of great significance in organic synthesis and drug development. Researchers can extract, separate and purify it with suitable organic solvents.
From the perspective of chemical properties, the compound molecule contains multiple active functional groups. Acetamide groups have certain nucleophilic properties and can participate in many nucleophilic substitution reactions. Pyridyl and thiophene rings endow the molecule with a conjugated structure, enhance its stability, and make it stand out in the fields of light and electricity. The carboxylate ethyl ester group has not only the commonality of esters, which can undergo reactions such as hydrolysis and alcoholysis, but also has unique reactivity due to the influence of surrounding groups. In organic synthesis, these functional groups provide many possible paths for the construction of complex compounds. Through rational design of reactions, molecular structures can be precisely modified and modified.
What is the price range of ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate in the market?
I do not know "ethyl 2- (acetylamino) -4- (pyridin-3-yl) thiophene-3-carboxylate" in the market price range. This compound is unusual and common, and its price is determined by many factors.
First, purity is the key factor. If the purity is very high, it is suitable for fine scientific research or high-end pharmaceutical fields, and the price must be high; if the purity is slightly lower, it is only for basic research or general experiments, and the price may be slightly reduced.
Second, the production scale also has an impact. Large-scale production, due to economies of scale, the unit cost may be reduced, and the price will also decrease; small-scale production, the cost is high, and the price will rise.
Third, the amount of market demand is related to the price. If the market demand for this product is strong and the supply is limited, the price may soar; if the demand is low and the supply is sufficient, the price will stabilize or decline.
Fourth, the cost of raw materials, the difficulty of synthesis, transportation and storage conditions all play a role in the price. Scarcity of raw materials, complex synthesis, and strict transportation and storage requirements will all lead to increased costs, which will affect the price.
However, because I do not know the specific market supply and demand, production conditions and other details of this compound, it is difficult to give the exact price range. If you want to know the details, you can consult chemical product suppliers, relevant scientific research reagent sales platforms, or find clues in chemical industry information and market survey reports.