Ethyl 2- {{[4- (azepan-1-ylsulfonyl) benzoyl] amino}} -5, 6-dihydro-4H-cyclopenta [b] What is the chemical structure of thiophene-3-carboxylate

"Ethyl + 2 - { { [ 4 - (azepan - 1 - ylsulfonyl) benzoyl] amino } } - 5,6 - dihydro - 4H - cyclopenta [b] thiophene - 3 - carboxylate" is the English name of an organic compound. To clarify its chemical structure, it should be analyzed according to the naming rules.

"ethyl", ethyl is also one of the substituents of the compound, which is connected to the main structure. " 2 - { { [ 4 - (azepan - 1 - ylsulfonyl) benzoyl] amino}} ", wherein" 4 - (azepan - 1 - ylsulfonyl) benzoyl "," azepan - 1 - ylsulfonyl "is an azaheptane - 1 - -ylsulfonyl group, connected to the 4th position of the benzoyl group; and this benzoylamino group is connected to the 2nd position of the main structure.

"5,6 - dihydro - 4H - cyclopenta [b] thiophene - 3 - carboxylate", "5,6 - dihydro - 4H - cyclopenta [b] thiophene" is 5,6 - dihydro - 4H - cyclopento [b] thiophene, which is the main ring structure; "3 - carboxylate" indicates that there is a carboxylic acid ester group attached to the third position of the ring, and the previous "ethyl" is the substituent of the carboxylic acid ester group, forming an ethyl ester structure.

In summary, the structure of this compound takes 5,6-dihydro-4H-cyclopento [b] thiophene as the parent ring, ethyl ester group at 3 position, and benzoyl] amino at 2 position. In this way, its chemical structure is roughly clear.

Ethyl 2- {{[4- (azepan-1-ylsulfonyl) benzoyl] amino}} -5, 6-dihydro-4H-cyclopenta [b] What are the physical properties of thiophene-3-carboxylate

Ethyl 2- {{[4- (azepan-1-ylsulfonyl) benzoyl] amino}} -5, 6-dihydro-4H-cyclopenta [b] thiophene-3-carboxylate is an organic compound, its physical properties are quite important, related to many properties and uses of this compound.

This compound is usually in a solid state, and its melting point is a key indicator to distinguish its purity and characteristics. Generally speaking, the accurate measurement of melting point requires specific experimental methods, such as melting point meters and other precision instruments. Due to factors such as the purity and crystal structure of the compound, the melting point is greatly affected, so the accurate determination of melting point is of great significance for the study of its physical properties. < Br >
Looking at its solubility, in terms of organic solvents, this compound exhibits a certain solubility in common organic solvents, such as ethanol and dichloromethane. Ethanol, as a common organic solvent, has a moderate polarity and can form interactions with some groups of the compound, such as hydrogen bonds, so that the compound can be dissolved in it. The polarity of dichloromethane is relatively small, but due to the characteristics of molecular structure, it also interacts moderately with the compound, so that the compound can be dissolved in it. However, in water, the solubility of this compound is poor. The polarity of water is extremely strong, and it interacts weakly with the hydrophobic part of the compound structure, making it difficult to dissolve.

The density of this compound is also an important physical property. Although the exact density needs to be determined experimentally, it can be roughly inferred based on its molecular structure and composition. Its molecules contain many carbon, hydrogen, oxygen, nitrogen, sulfur and other atoms, and the atomic weight and spatial arrangement have a significant impact on the density. Due to the presence of benzene rings and heterocycles in the molecular structure, the molecules are tightly packed, which may make the density relatively large.

In addition, the color state of the compound cannot be ignored. Under normal conditions, ethyl 2- {{[4- (azepan-1-ylsulfonyl) benzoyl] amino}} -5, 6-dihydro-4H-cyclopenta [b] thiophene-3-carboxylate may be white to off-white solids. This color state characteristic not only reflects its own purity, but also hints at its stability and reactivity in different environments.

In summary, the melting point, solubility, density, color state and other physical properties of this compound are the key to further exploring its characteristics and applications, and are of great significance in many fields such as organic synthesis and drug development.

What is the synthesis method of ethyl 2- {[4- (azepan-1-ylsulfonyl) benzoyl] amino}} -5, 6-dihydro-4H-cyclopenta [b] thiophene-3-carboxylate

Now ethyl + 2 - {[{4 - (azepan - 1 - ylsulfonyl) benzoyl} amino]} - 5,6 - dihydro - 4H - cyclopenta [b] thiophene - 3 - carboxylate, the synthesis method, as follows.

First take 4- (azepan - 1 - ylsulfonyl) benzoic acid and react with a suitable reagent, such as thionyl chloride, to obtain 4- (azepan - 1 - ylsulfonyl) benzoyl chloride. This reaction requires heating and refluxing in a suitable solvent, such as dichloromethane, so that the reaction can proceed fully. After the reaction is completed, the solvent and unreacted sulfinyl chloride are removed by distillation to obtain pure 4- (azepan - 1 - ylsulfonyl) benzoyl chloride.

Take another 5,6 - dihydro - 4H - cyclopenta [b] thiophene - 3 - carboxylic acid ethyl ester and mix it with a base such as triethylamine in a suitable solvent such as dichloromethane. After stirring, slowly add the resulting 4- (azepan - 1 - ylsulfonyl) benzoyl chloride dropwise. This reaction is carried out at a low temperature, such as between 0 ° C and 5 ° C, to avoid side reactions. After the dropwise addition is completed, the reaction mixture is warmed to room temperature, and the reaction is continued to be stirred for several hours.

After the reaction is completed, the reaction mixture is washed with a dilute hydrochloric acid solution to remove unreacted bases and other impurities. The organic phase is then separated and dried with anhydrous sodium sulfate. Finally, the solvent is removed by distillation under reduced pressure to obtain a crude product. The crude product is purified by column chromatography, etc., using an appropriate eluent, such as a mixed solvent of petroleum ether and ethyl acetate, and adjusting in proportion to obtain pure ethyl + 2 - {{4- (azepan - 1 - ylsulfonyl) benzoyl} amino]} - 5,6 - dihydro - 4H - cyclopenta [b] thiophene - 3 - carboxylate.

Ethyl 2- {[4- (azepan-1-ylsulfonyl) benzoyl] amino}} -5, 6-dihydro-4H-cyclopenta [b] What are the application fields of thiophene-3-carboxylate

Ethyl 2- {{[4- (azepan-1-ylsulfonyl) benzoyl] amino}} -5, 6-dihydro-4H-cyclopenta [b] thiophene-3-carboxylate is an organic compound. Looking at the structural properties of this compound, its application field is quite extensive.

In the field of medicinal chemistry, its unique molecular structure may be used as a lead compound for drug development. Specific functional groups in its structure, such as sulfonyl and benzoyl amino groups, may interact with specific targets in vivo, showing potential pharmacological activities, such as anti-inflammatory and anti-tumor equivalents. Gein sulfonyl groups can often affect the hydrophilicity and electron cloud distribution of compounds, which is conducive to binding to protein targets; benzoamide groups may participate in the formation of hydrogen bonds and enhance the interaction with biological macromolecules.

In the field of materials science, this compound may be used as a building unit for the preparation of functional materials. Its complex structure endows molecules with specific rigidity and flexibility, or it can be used to synthesize materials with special optical and electrical properties. For example, after appropriate modification and polymerization, materials with fluorescent properties may be prepared, which can be used in optical sensing, display technology, etc.

In the field of organic synthetic chemistry, this compound can be used as a key intermediate for the synthesis of more complex organic molecules. With the various reaction check points in its structure, chemists can modify and derive its structure through various organic reactions, such as nucleophilic substitution, electrophilic addition, etc., to expand the structural diversity of organic compounds, and provide new opportunities and directions for the development of organic synthetic chemistry.

Ethyl 2- {{[4- (azepan-1-ylsulfonyl) benzoyl] amino}} -5, 6-dihydro-4H-cyclopenta [b] What is the market outlook for thiophene-3-carboxylate

Ethyl - 2 - { { [ 4 - (azacycloheptane - 1 - sulfonyl) benzoyl] amino } } - 5,6 - dihydro - 4H - cyclopento [b] thiophene - 3 - carboxylic acid ester, this compound has great potential opportunities in terms of market prospects, considering the current situation of pharmaceutical research and development.

In the field of innovative drug exploration, its unique chemical structure may be the key to unlocking new therapeutic targets. Pharmaceutical researchers often seek compounds with novel structures and activities to develop good drugs for difficult diseases. This compound has a special structure or unique pharmacological activity. If carefully studied, it may make a name for itself in the treatment of many diseases such as anti-tumor and anti-inflammatory.

However, the road to the market is not smooth. R & D costs are huge, and from basic research to clinical trials, it requires a lot of manpower, material and financial resources. And the approval process of new drugs is complicated, and it needs to go through many rigorous tests to prove its safety and effectiveness.

Furthermore, competition is also a factor that cannot be ignored. The pharmaceutical industry is booming, and many pharmaceutical companies are committed to innovative drug research and development. If you want to make progress in the development of this compound, you need to have a keen eye and an efficient R & D strategy.

Although there are many challenges, opportunities coexist. If we can make good use of its structural advantages to break through the research and development dilemma, we may be able to gain a place in the pharmaceutical market, bring good news to patients, and contribute to the pharmaceutical industry.