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Ethyl 2- [[ (2E) -3- (furan-2-yl) prop-2-enoyl] amino] -4, what is the chemical structure of 5-dimethylthiophene-3-carboxylate
This is about the chemical structure of the compound "ethyl 2- [[ (2E) -3- (furan-2-yl) prop-2-enoyl] amino] -4, 5-dimethylthiophene-3-carboxylate". Its structural analysis is as follows:
- The main frame of this compound contains a thiophene ring, and the thiophene ring is connected with a carboxylic acid ethyl ester group at the 3rd position, that is, -COOCH < CH < CH 🥰 structure. This ethyl ester group is obtained by forming an ester of carboxyl and ethanol.
- The 4th and 5th positions of the thiophene ring are each connected with a methyl group, that is, a -CH group. < Br > -thiophene ring is connected at 2 positions to an amino-containing structure, which is connected to (2E) -3- (furan-2-yl) acryloyl group. (2E) -3- (furan-2-yl) acryloyl group contains a furan ring, which is connected by an allyl group, and the double bond configuration is E-type, that is, the two larger groups are on the opposite side of the double bond.
-Overall, this compound is derived from the thiophene ring. Through the connection of different functional groups, a specific chemical structure is constructed. The functional groups of each part interact with each other, giving the compound unique chemical properties and potential activities.
Ethyl 2- [[ (2E) -3- (furan-2-yl) prop-2-enoyl] amino] -4, what are the physical properties of 5-dimethylthiophene-3-carboxylate
Ethyl-2 - [ (E) -3 - (furan-2-yl) acryloyl) amino] -4,5 -dimethylthiophene-3 -carboxylic acid ester, the physical properties of this substance are as follows:
Looking at its morphology, it is mostly solid at room temperature, but the specific properties may vary depending on the preparation method and purity. Its melting point is related to the temperature at which the substance is melted by heat, which is an important physical constant, but I have not obtained the exact value. < Br >
In terms of solubility, in organic solvents, such as common ethanol and acetone, there may be a certain solubility, and the lid has good affinity with organic solvents because it contains many organic groups in its molecular structure; while in water, due to the large proportion of hydrophobic groups, the solubility may be limited.
When it comes to density, although I don't know the exact value, it is speculated according to its structure, or it is similar to the density of common organic compounds, and is between water and most organic solvents.
The volatility of this substance is due to its solid state and relatively strong intermolecular forces, and the volatility is low or low. Its odor, with common sense, contains heterocyclic structures such as furans and thiophenes, or has a special organic odor, but the exact smell needs to be known by actual sniffing.
Overall, in order to know the exact values of the physical properties of this thing, it needs to be accurately determined by experiments, so that its physical characteristics can be fully grasped.
What is the synthesis method of ethyl 2- [[ (2E) -3- (furan-2-yl) prop-2-enoyl] amino] -4, 5-dimethylthiophene-3-carboxylate
The method of preparing ethyl 2- [[ (2E) -3- (furan-2-yl) prop-2-enoyl] amino] -4, 5-dimethylthiophene-3-carboxylate, can be done according to the following steps.
First, start with 4,5-dimethyl-3-thiophenecarboxylic acid. React it with a suitable reagent to convert the carboxyl group to a more active form, such as acid chloride. This step can be done by adding a chlorination reagent, such as thionyl chloride (SOCl -2), to 4,5-dimethyl-3-thiophenecarboxylic acid and stirring the reaction at a suitable temperature. Sulfuryl chloride reacts with a carboxyl group to form 4,5-dimethyl-3-thiophenoformyl chloride, while sulfur dioxide and hydrogen chloride gas escape.
Times, prepare (2E) -3- (furan-2-yl) prop-2-enoyl moiety. This structure can be constructed by condensation reaction with suitable reagents starting from furfural. For example, furfural reacts with malonic acid at an appropriate temperature in the presence of a basic catalyst such as pyridine to produce (2E) -3- (furan-2-yl) acrylic acid. Subsequently, this acid is converted to its corresponding form of acid chloride, which can also be treated with thionyl chloride to give (2E) -3- (furan-2-yl) prop-2-enoyl chloride.
After that, 4,5-dimethyl-3-thiophenoyl chloride reacts with (2E) -3- (furan-2-yl) prop-2-enoyl chloride. In an alkaline environment, such as triethylamine, the two carry out a condensation reaction to produce ethyl 2- [[ (2E) -3- (furan-2-yl) prop-2-enoyl] amino] -4, 5-dimethylthiophene-3-carboxylate. During the reaction, triethylamine can neutralize the generated hydrogen chloride and promote the forward reaction.
After the reaction is completed, the product needs to be isolated and purified. The product can be separated from the reaction mixture by column chromatography with suitable stationary and mobile phases to obtain high purity ethyl 2- [[ (2E) -3- (furan - 2 - yl) prop - 2 - enoyl] amino] -4, 5-dimethylthiophene-3-carboxylate.
Ethyl 2- [[ (2E) -3- (furan-2-yl) prop-2-enoyl] amino] -4, what are the application fields of 5-dimethylthiophene-3-carboxylate
Ethyl 2- [ (E) -3- (furan-2-yl) acrylamino] -4,5-dimethylthiophene-3-carboxylic acid ester, this compound has important applications in medicine, materials science, agricultural chemistry and many other fields.
In the field of medicine, due to its unique chemical structure, it has the potential to regulate biological activity. Or it can be used as a lead compound to develop new drugs through structural optimization. The furan and thiophene groups in its structure endow the compound with specific lipophilic and electronic properties, or can interact with specific targets in vivo, such as certain enzymes or receptors, which is expected to develop therapeutic drugs for specific diseases, such as inflammatory diseases, tumors, etc.
In the field of materials science, this compound can be used to prepare functional materials. Due to its special conjugated structure or good photoelectric properties, it can be applied to optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and organic solar cells. The ordered arrangement and interaction of its molecular structures can affect the electrical and optical properties of materials, and help to develop high-performance and low-cost new optoelectronic device materials.
In the field of agricultural chemistry, it may be used as the basis for the creation of potential pesticides. It exhibits biological activity against pests such as insects and fungi. The uniqueness of its structure may enable it to interfere with the physiological processes of pests, such as hindering the transmission of the pest's nervous system, or inhibiting the synthesis of fungal cell walls, thus exerting insecticidal and bactericidal effects and providing a new direction for the development of environment-friendly pesticides.
Ethyl 2- [[ (2E) -3- (furan-2-yl) prop-2-enoyl] amino] -4, what is the market prospect of 5-dimethylthiophene-3-carboxylate
There is a product called ethyl + 2 - [[ (2E) -3- (furan - 2 - yl) prop - 2 - enoyl] amino] -4,5 - dimethylthiophene - 3 - carboxylate. The prospect of this product in the market is quite popular.
Looking at the current various industries and the field of organic synthesis, there is a great demand for novel compounds. This compound has a unique structure and contains furan and thiophene groups. It may be used as a key building block in organic synthesis, providing the possibility to create novel and complex molecules. Therefore, it is expected to have a place in the market of fine chemical raw materials.
In the field of pharmaceutical research and development, molecules with biological activity are often explored. The compound has a special structure, which may endow it with potential pharmacological activities, such as anti-inflammatory, antibacterial, etc. If its activity is confirmed through in-depth pharmacological research, the pharmaceutical market has broad prospects, or it may become a new type of drug lead compound, which has attracted many pharmaceutical companies to invest in research and development.
In the field of materials science, functional materials have been explored more and more in recent years. The structural properties of this compound may make it stand out in optoelectronic materials. If it can show unique optical and electrical properties, it can also get a share of the optoelectronic device manufacturing market.
However, its marketing activities also pose challenges. The synthesis process may need to be optimized to reduce costs and yield. And subject to rigorous safety and environmental assessments to ensure compliance with regulatory requirements.
In summary, ethyl + 2- [[ (2E) -3- (furan-2-yl) prop-2-enoyl] amino] -4,5-dimethylthiophene-3-carboxylate Although it faces challenges, it has potential in organic synthesis, pharmaceutical research and development, materials science and other market fields. Over time, it may shine.