What is the chemical structure of ethyl 2- {[ (2E) -3- (4-methoxyphenyl) prop-2-enoyl] amino} -4, 5, 6, 7-tetrahydro-1-benzothiophene-3-carboxylate?

This is the name of the organic compound, according to this name to draw its chemical structure, the steps are as follows:
1. ** Analysis of the main structure **: The main body is "4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate ethyl ester", this structure contains a benzothiophene ring, in which the 4, 5, 6, and 7 positions of the benzene ring are in the hydrogenated state, and there is a carboxylate ethyl ester group ($- COOCH_2CH_3 $) at the 3 position. This is the core structure of the whole molecule, which lays the basic skeleton.
2. ** Determine the position and structure of the substituent **: "2 - {[ (2E) -3- (4-methoxyphenyl) propyl-2-enoyl] amino}" is another key substituent. This substituent is connected to the 2 positions of the main structure and has a specific configuration and structure. Among them, the configuration of the " (2E) " double bond is E type, and the configuration of "3 - (4-methoxyphenyl) propyl-2-enoyl" contains the acryloyl structure of the 4-methoxyphenyl group, which is connected to the amino group through the acyl group, and then connected to the main 2 positions.
3. ** Step-by-step construction of chemical structure **: First draw the structure of 4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl ester to ensure that the hydrogenation position of the benzothiophene ring is correctly connected to the carboxylic acid ethyl ester. Then, according to the description of the substituent, add "{[ (2E) -3- (4-methoxyphenyl) propyl-2-enoyl] amino}" in position 2. When drawing, be sure to ensure that the E-type configuration of the double bond is correct, and the connection order and bonding method between the atoms are accurate.

In this way, the chemical structure of ethyl 2 - {[ (2E) -3- (4-methoxyphenyl) propyl-2-enyl] amino} -4,5,6,7 -tetrahydro-1-benzothiophene-3-carboxylate can be accurately drawn.

What are the physical properties of ethyl 2- {[ (2E) -3- (4-methoxyphenyl) prop-2-enoyl] amino} -4, 5, 6, 7-tetrahydro-1-benzothiophene-3-carboxylate?

This is an organic compound named "Ethyl-2 - {[ (E) -3- (4-methoxyphenyl) propyl-2-enyl] amino} -4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ester". Its physical properties are as follows:

In terms of appearance, or in the form of white to light yellow crystalline powder, because the molecular structure is mostly hydrocarbons and various functional groups, it has a certain hydrophobicity, so the solubility in water is very small, but it can be soluble in common organic solvents, such as chloroform, dichloromethane, acetone, etc. This property is due to the fact that non-polar structures such as benzene rings and thiophene rings account for a large proportion of molecules, and the force on water molecules is weak, but they can form intermolecular forces with organic solvents.

In terms of melting and boiling point, the melting point or in a specific range, there are Van der Waals forces, hydrogen bonds and other interactions between molecules, which require specific energy to overcome before the phase state transition can be induced. The exact value depends on the interaction strength between molecules. Functional groups such as amide bonds and ester groups can form hydrogen bonds, which can enhance the intermolecular force and increase the melting point. The boiling point is also affected by the intermolecular force and the relative molecular weight. The larger the relative molecular weight and the stronger the intermolecular force, the higher the boiling point.

The compound has certain stability, and its molecular structure may change under extreme conditions such as strong acid, strong base or high temperature. Because functional groups such as amide bonds and ester groups are sensitive to acid and base, they can be hydrolyzed under the catalysis of acid or base, resulting in molecular structure damage. In high temperature environments, or due to the increase of intra-molecular energy, chemical bond cracking and rearrangement are triggered.

What is the synthesis method of ethyl 2- {[ (2E) -3- (4-methoxyphenyl) prop-2-enoyl] amino} -4, 5, 6, 7-tetrahydro-1-benzothiophene-3-carboxylate?

Alas! To make ethyl + 2 - {[ (2E) -3- (4 - methoxyphenyl) prop - 2 - enoyl] amino} - 4,5,6,7 - tetrahydro - 1 - benzothiophene - 3 - carboxylate, you can follow the following ancient method.

First, 4 - methoxybenzaldehyde and malonic acid under the catalysis of pyridine, perform Knoevenagel condensation to obtain (2E) -3- (4 - methoxyphenyl) acrylic acid. Then it is heated with sulfoxide chloride to convert it into (2E) -3- (4 - methoxyphenyl) propionyl chloride.

Take another 4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl ester, co-place it with potassium carbonate in an appropriate solvent, such as N, N-dimethylformamide (DMF), and stir well. Then slowly add the (2E) -3- (4-methoxyphenyl) propionyl chloride obtained above, and maintain a certain temperature, such as near room temperature, when stirring the reaction number continuously. This step is the process of amidation, through the reaction of acid chloride and amino groups in ethyl carboxylate derivatives, to construct the key structure of the target molecule.

After the reaction is completed, pour the reaction solution into an appropriate amount of ice water, adjust the pH value with dilute acid or dilute base, and make the product precipitate. After filtration, washing, drying and other operations, the crude product is obtained. Then refined by column chromatography or recrystallization, pure ethyl + 2 - {[ (2E) -3- (4 - methoxyphenyl) prop - 2 - enoyl] amino} -4, 5,6,7 - tetrahydro - 1 - benzothiophene - 3 - carboxylate can be obtained. This method of synthesis requires attention to the control of the reaction conditions at each step. The choice of solvent, the temperature, and the proportion of reactants are all crucial to success and failure, and must be handled with caution.

What are the application fields of ethyl 2- {[ (2E) -3- (4-methoxyphenyl) prop-2-enoyl] amino} -4, 5, 6, 7-tetrahydro-1-benzothiophene-3-carboxylate?

Ethyl + 2 - {[ (2E) -3- (4 - methoxyphenyl) prop - 2 - enoyl] amino} -4, 5, 6, 7 - tetrahydro - 1 - benzothiophene - 3 - carboxylate, this is an organic compound with potential applications in pharmaceutical research and development, materials science and other fields.

In the field of pharmaceutical research and development, many organic compounds can be modified and modified to have specific biological activities or become drug lead compounds. This compound has a unique structure and contains specific functional groups that may interact with specific targets in organisms. For example, structural moieties such as 4-methoxyphenyl, enamido, and benzothiophene carboxylates may interact with specific proteins, enzymes, or receptors, affecting physiological and pathological processes in organisms, laying the foundation for the development of new drugs, such as drugs for the treatment of diseases such as inflammation and tumors.

In the field of materials science, organic compounds often attract much attention due to their unique electrical and optical properties. The structural characteristics of the compound may endow it with unique photoelectric properties. For example, benzothiophene structural units in some materials can enhance the degree of conjugation of molecules, affecting the electron transport and luminescence properties of materials. Therefore, it can be explored to apply it to the research and development of organic Light Emitting Diode (OLED), organic solar cells and other optoelectronic device materials to improve the performance and efficiency of materials.

Furthermore, in the field of organic synthetic chemistry, this compound can be used as an important intermediate. Due to its complex structure and multiple functional groups, organic chemists can further derive it through various organic reactions to synthesize compounds with more complex and diverse structures, expand the library of organic compounds, and promote the development and innovation of organic synthesis methodologies.

What is the market outlook for ethyl 2- {[ (2E) -3- (4-methoxyphenyl) prop-2-enoyl] amino} -4, 5, 6, 7-tetrahydro-1-benzothiophene-3-carboxylate?

Concept ethyl + 2 - {[ (2E) -3- (4 - methoxyphenyl) prop - 2 - enoyl] amino} -4, 5, 6, 7 - tetrahydro - 1 - benzothiophene - 3 - carboxylate This product is worth exploring in the current market prospect.

This product may be emerging in the field of medicinal chemistry. Because the structures involved contain specific aryl groups and alkenyl groups, such structures are often key active parts in the process of drug development. After many studies, compounds with similar structures or targets for specific diseases have potential effects. For example, the 4-methoxyphenyl group in its structure may affect the interaction between compounds and biomacromolecules, and by forming suitable hydrophobic or hydrogen bonds with the receptor, it may exhibit pharmacological activity.

In the field of materials science, there are also opportunities for potential applications. Its unique molecular structure may endow materials with specific physical and chemical properties. For example, in some organic optoelectronic materials, such compounds containing sulfur heterocycles combined with conjugated structures may affect the properties of charge transport and optical absorption of materials, providing new ideas and approaches for the creation of new functional materials.

However, the road to marketing activities is not smooth. The complexity of the synthesis process may be a major constraint. The preparation process may require multi-step reactions, and the reaction conditions are strict, and the cost remains high, which is not conducive to large-scale production and application. Furthermore, the relevant biological activity and safety data still need more detailed research. Only through a comprehensive and in-depth evaluation can the safety and effectiveness of its application in the market be guaranteed.

In summary, ethyl + 2 - {[ (2E) -3- (4 - methoxyphenyl) prop - 2 - enoyl] amino} -4, 5, 6, 7 - tetrahydro - 1 - benzothiophene - 3 - carboxylate is promising, but it is still necessary for researchers to make great progress in synthesis optimization, performance research, etc., in order to overcome many problems, in order to realize its commercial value and application potential.