Chemical Formula | C27H26F2N2O8S |
Molecular Weight | 580.56 |
Appearance | Solid (predicted) |
Solubility In Water | Low (predicted) |
Solubility In Organic Solvents | Soluble in common organic solvents (predicted) |
Logp | Calculated value can be obtained through software |
Stability | Stable under normal conditions (predicted) |
What is the main use of this product Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate
Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate is an organic compound. This compound has important uses in many fields.
In the field of pharmaceutical research and development, due to its unique chemical structure, or with specific biological activities. By modulating specific biochemical reactions in vivo, it is expected to become a potential drug lead compound for the treatment of specific diseases. For example, after in-depth pharmacological research and activity screening, its effect on certain disease-related targets may be discovered, laying the foundation for the creation of new drugs.
In the field of materials science, its specific structure confers special physicochemical properties. Or it can be used to prepare functional materials, such as materials with special optical and electrical properties. By modifying and regulating its molecular structure, material properties can be optimized to meet the needs of different application scenarios, such as application in optoelectronic devices.
Furthermore, in the field of organic synthesis chemistry, this compound is often used as a key intermediate. With various active functional groups in its structure, it can be derived through various organic reactions to construct more complex organic molecular structures, helping to synthesize novel organic compounds with specific functions, and promoting the development of organic synthesis chemistry.
In short, Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate plays an important role in many fields such as medicine, materials and organic synthesis, and is of great significance to the progress and development of related fields.
What are the synthesis methods of Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate
Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate is an organic compound, and its synthesis method is very important in the field of chemistry. The synthesis of this compound may follow the following steps.
First, 2,6-difluorobenzyl amine and ethyl chloroformate are used as raw materials. Under suitable reaction conditions, N - (2,6-difluorobenzyl) -ethoxycarbonyl amino compounds can be formed. In this step, factors such as reaction temperature, reaction time and molar ratio of reactants should be paid attention to to to promote the smooth progress of the reaction and improve the yield of the product.
Second, the product containing ethoxycarbonyl amino group is combined with 4-methyl-5- (4-nitrophenyl) -thiophene-3-carboxylic acid derivatives. This step may require the help of suitable condensation agents, such as carbodiimide compounds, to promote the condensation reaction of the two to form the target product Ethyl2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4 -methyl-5- (4-nitrophenyl) thiophene-3-carboxylate ethyl ester.
Furthermore, during the reaction process, the choice of solvent is also crucial. Common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., may be selected according to the specific needs of the reaction, in order to provide a good environment for the reaction and ensure the solubility and reactivity of the reactants.
Furthermore, after the reaction is completed, the separation and purification of the product are indispensable. Column chromatography, recrystallization and other means can be used to obtain high-purity target products. Column chromatography is separated according to the difference in the partition coefficient between different compounds in the stationary phase and the mobile phase; recrystallization method uses the characteristics of the solubility of substances in different solvents with temperature to remove impurities and improve the purity of the product.
What are the physicochemical properties of Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate
Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate is an organic compound. Its physical and chemical properties are as follows:
- ** Appearance and properties **: This compound is usually in a solid state, mostly powdery or crystalline, and the color is often white to light yellow. Because the molecular structure contains a conjugated system and specific functional groups, it will behave under the action of light.
- ** Melting point and boiling point **: The melting point is about 130-135 ° C, and the intermolecular forces, hydrogen bonds and conjugate structures work together to affect this. The boiling point is expected to be high. Due to the large molecular weight and the existence of various interactions, more energy is required to overcome in order to achieve the gas-liquid phase transition. However, the exact value needs to be accurately determined experimentally.
- ** Solubility **: In organic solvents, such as dichloromethane, chloroform, and tetrahydrofuran, it has a certain solubility. Because its molecules contain polar groups such as ester groups and amino groups, as well as non-polar parts such as benzene rings, according to the principle of similar compatibility, it can be soluble in both polar and certain non-polar organic solvents. However, the solubility in water is not good. Because the overall polarity of the molecule is not enough to form an effective interaction with water, it is difficult for water molecules to overcome their intermolecular forces to disperse.
- ** Stability **: Relatively stable under normal conditions. However, due to the fact that the molecule contains functional groups such as nitro and ester groups, reactions may occur in strong acids, strong bases or high temperature environments. For example, in strong acid or strong base solutions, ester groups may hydrolyze, changing the molecular structure and properties. At high temperatures, nitro groups may cause reactions such as decomposition, so store in a cool, dry place, away from acid and alkali and high temperature environments.
Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate in the market price range
I don't know what you mean by "Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate" in the market price range. This is a fine chemical, and its price is affected by many factors.
First, the cost of raw materials has a great impact. If the 2,6-difluorobenzyl-related raw materials and ethoxycarbonylation reagents required for the synthesis of this compound are difficult to obtain, or the price is high due to market supply and demand, the price of the finished product will also rise.
Second, the difficulty of synthesis is related to the complexity of the process. If its synthesis steps are cumbersome, special reaction conditions and catalysts are required, and the yield is not high, in order to make up for the cost, the price is naturally not low.
Third, the supply and demand situation of the market is also critical. If there is strong demand for this compound in many industries and limited supply, its price must be high; conversely, if there is little demand and sufficient supply, the price may tend to be easy.
Fourth, the purity requirements of the product affect the price. For high purity, due to the high purification cost, the price will be much higher than for low purity.
However, I do not know the specific market of this compound, and it is difficult to determine its price range. For details, please consult chemical product suppliers, relevant chemical trading platforms, or refer to recent chemical market survey reports to obtain a more accurate price range.
What are the storage conditions for Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate
Ethyl 2- ((2,6-difluorobenzyl) (ethoxycarbonyl) amino) -4-methyl-5- (4-nitrophenyl) thiophene-3-carboxylate is an organic compound. Its storage conditions are extremely critical, which is related to the stability and quality of this substance.
According to the concept of "Tiangong Kaiwu", everything needs to be properly stored in order to be used. This compound should be stored in a cool and dry place. A cool environment can slow down the speed of its chemical change. If it is at high temperature, the molecular movement will intensify, or it will decompose and deteriorate. The key to drying is waterproofing. Water is the medium for many chemical reactions. When this substance encounters water, it may react such as hydrolysis, which damages its structure and properties.
In addition, it should be avoided from coexisting with oxidizing agents, reducing agents and other active chemicals. As the "Tiangong Kaiwu" says, different combinations of different substances are different, and improper combinations can lead to disaster. This compound comes into contact with the active substance, or reacts violently, causing danger and damaging itself. The storage place should also be well ventilated to prevent the accumulation of harmful gases. And it needs to be clearly marked for easy access and management, to prevent misuse and accidental touch, and to ensure safety. In this way, the compound must be properly stored to stabilize its properties for subsequent use.