What is the chemical structure of dimethyl 5- [ (4-methoxybenzoyl) amino] -3-methylthiophene-2, 4-dicarboxylate?

The chemical structure of "dimethyl + 5 - [ (4 - methoxybenzoyl) amino] - 3 - methylthiophene - 2,4 - dicarboxylate" is the category of organic chemistry.

Looking at its name, "dimethyl" shows dimethyl. "5 - [ (4 - methoxybenzoyl) amino]", it can be seen that there is a group connected at the 5th position, which is (4 - methoxybenzoyl) amino. Among them, "4 - methoxybenzoyl" has a methoxybenzoyl group at the 4th position, and "amino" is an amino group. " "3-Methylthiophene", is a thiophene ring with methyl at the 3rd position, and the thiophene ring is a sulfur-containing five-membered heterocycle. "2,4-dicarboxylate", indicating that there are dicarboxylate groups connected at the 2nd and 4th positions of the thiophene ring.

In short, its chemical structure is based on the thiophene ring as the core, with methyl groups at the 3rd position, carboxylate groups at the 2nd and 4th positions, and amino groups at the 5th position, and dimethyl groups as a whole. This compound has a delicate structure, and the groups are connected to each other, which may be important in the fields of organic synthesis, medicinal chemistry, etc. In this way, its chemical structure is roughly clear.

What are the main uses of dimethyl 5- [ (4-methoxybenzoyl) amino] -3-methylthiophene-2, 4-dicarboxylate?

Dimethyl 5- [ (4-methoxybenzoyl) amino] -3-methylthiophene-2, 4-dicarboxylate, Chinese name or 5- [ (4-methoxybenzoyl) amino] -3 -methylthiophene-2,4 -dicarboxylate. This substance is quite versatile and is often used as a key intermediate in the field of medical chemistry to assist in the synthesis of many drugs. Due to its unique chemical structure, it can interact with specific targets in organisms, which is of great significance in the development of new drugs and the exploration of potential therapeutic methods.

In the field of materials science, it also has application value. It can participate in the creation of functional materials. After special processing, the materials may have unique optical and electrical properties, and play a key role in frontier fields such as optoelectronic devices and sensors. Such as the preparation of sensors sensitive to specific substances to achieve accurate detection of targets.

In the field of organic synthesis, as an important raw material, with its active groups, it can construct complex organic molecular structures through various chemical reactions, providing a key foundation and possibility for the synthesis of new organic compounds and the expansion of the library of organic chemical substances. In short, dimethyl 5- [ (4-methoxybenzoyl) amino] -3-methylthiophene-2, 4-dicarboxylate plays an indispensable role in many scientific research and industrial fields, promoting the continuous progress and development of related fields.

What is the synthesis method of dimethyl 5- [ (4-methoxybenzoyl) amino] -3-methylthiophene-2, 4-dicarboxylate?

To prepare dimethyl ester 5- [ (4-methoxybenzoyl) amino] -3-methylthiophene-2,4-dicarboxylic acid ester, the method is as follows:

First take 3-methylthiophene-2,4-dicarboxylic acid, mix it with methanol in an appropriate ratio, add an appropriate amount of concentrated sulfuric acid as a catalyst in the reaction kettle. Heat up to a suitable temperature, maintain this temperature and continue to stir, and carry out esterification reaction. This process requires careful monitoring of the progress of the reaction. By thin-layer chromatography or other suitable detection methods, when the reaction reaches the desired level, 3-methylthiophene-2,4-dicarboxylic acid dimethyl ester is obtained. < Br >
Then, take another 4-methoxybenzoic acid, mix it with dichlorosulfoxide, add a little N, N-dimethylformamide as a catalyst, heat and reflux until the reaction is complete, to obtain 4-methoxybenzoyl chloride.

Dissolve the prepared 3-methylthiophene-2,4-dicarboxylate with an appropriate amount of base (such as triethylamine) in a suitable organic solvent (such as dichloromethane). Under low temperature and stirring state, slowly add the dichloromethane solution of 4-methoxybenzoyl chloride dropwise. Add it dropwise, gradually heat up to room temperature, and continue to stir the reaction. After the reaction is completed, the product is purified by washing, drying, column chromatography and other steps to obtain dimethyl ester 5- [ (4-methoxybenzoyl) amino] -3-methylthiophene-2,4-dicarboxylate. The whole synthesis process requires precise control of each reaction condition to ensure smooth and efficient reaction to obtain high yield and purity products.

What are the physicochemical properties of dimethyl 5- [ (4-methoxybenzoyl) amino] -3-methylthiophene-2, 4-dicarboxylate?

The physicochemical properties of dimethyl ester 5- [ (4-methoxybenzoyl) amino] -3-methylthiophene-2,4-dicarboxylate are quite important.

In terms of its physical properties, this compound is usually in a solid state, due to the existence of various forces between molecules, such as van der Waals force, hydrogen bonds, etc., which promote the formation of a relatively regular arrangement structure. Its melting point should be a key physical property, but the exact value needs to be determined by precise experiments. The level of melting point is closely related to the molecular structure. Factors such as molecular symmetry, the type and location of substituents, etc., all affect the melting point.

Looking at its chemical properties, the molecule contains methoxybenzoyl amino groups. This part of the electron cloud density of the benzene ring increases due to the power supply effect of the methoxy group, so it is more prone to electrophilic substitution reactions. For example, under appropriate conditions, it can react with electrophilic reagents such as halogenated hydrocarbons. The methyl groups on the thiophene ring also affect the electron cloud distribution of the thiophene ring and change its reactivity. At the same time, the chemical properties of the ester group are relatively active, and hydrolysis can occur under acid or base catalysis. Hydrolysis under acidic conditions can produce corresponding carboxylic acids and alcohols, and hydrolysis under alkaline conditions can produce carboxylic salts and alcohols. The amino groups in this compound have a certain alkalinity and can neutralize with acids to form corresponding salts. This compound may have potential application value in the field of organic synthesis, which can realize the construction of complex organic molecules by reacting with its different functional groups.

What is the price range of dimethyl 5- [ (4-methoxybenzoyl) amino] -3-methylthiophene-2, 4-dicarboxylate in the market?

I have not heard of "dimethyl 5 - [ (4 - methoxybenzoyl) amino] - 3 - methylthiophene - 2,4 - dicarboxylate" in the market price range. The name of this compound is quite complex and belongs to the category of organic chemistry. Although the price of a chemical substance often varies depending on purity, supply and demand, and preparation methods. However, I have not received the exact information on the market conditions of this particular compound, and there is no way to say its price range. Or when you consult a merchant specializing in chemical reagents, or check an information platform for the trading of chemical raw materials, you can get an idea of its price. The market conditions of chemical substances are often changeable, and the prices are also different at different sources and in different quantities. Therefore, if you want to know the details, you need to search for the supply and marketing information in the market carefully.