diethyl 5-{[(2E)-3-(4-methoxyphenyl)prop-2-enoyl]amino}-3-methylthiophene-2,4-dicarboxylate

This is an organic compound named "diethyl-5- { ((E) -3- (4-methoxyphenyl) propyl-2-enyl) amino} -3-methylthiophene-2,4-dicarboxylate". Looking at its name, it can be seen that this compound is composed of several parts. "Diethyl" indicates that there are two ethyl groups (\ (C_2H_5 -\)) connected to it; "thiophene" is a sulfur-containing five-membered heterocyclic structure, which is the core skeleton of the compound. At the 3rd position of the thiophene ring, there is a methyl group (\ (CH_3\)), and at the 5th position, there is a complex substituent. This substituent starts with an amide structure, i.e. "{ ((E) -3- (4-methoxyphenyl) propane-2-enoyl) amino}", where " (E) " represents the configuration of the double bond is trans, "3- (4-methoxyphenyl) propane-2-enoyl" describes an acyl moiety connected to an amino group, this acyl group contains a 4-methoxyphenyl group (\ (CH_3O - C_6H_4 -\)), and the ethylenically bond is in the 2 position; the 2 and 4 positions of the thiophene ring are each connected with a carboxyl group (\ (-COOH\)), but here it is a dicarboxylic acid ester, that is, one of the carboxyl groups The hydroxyl group is replaced by an ethoxy group (\ (- OC_2H_5\)) to form the corresponding ester group. Overall, this compound has a complex structure and is composed of a variety of functional groups and specific connection methods.

This is diethyl 5- { (2E) -3 - (4-methoxyphenyl) propane-2-enylamino} -3 -methylthiophene-2,4-dicarboxylic acid ester. Its physical properties are as follows:
From the perspective of this, this substance may be a solid, and the color may vary depending on the purity. The pure product is often nearly colorless to light yellow. Because the molecule has a conjugated system and polar groups, it may be a certain color.
Its melting point, determined under specific conditions, is one of the properties of the substance. The atoms in the molecule are arranged in an orderly manner through chemical bonds. When heated to a certain temperature, the lattice can be overcome, the crystal structure disintegrates, and a phase transition occurs. However, the specific melting point value needs to be accurately determined by experiment, and it may be biased due to different experimental conditions.
In terms of solubility, the molecule contains ester groups, amino groups, methoxy groups and other groups. The ester group and the methoxy group have a certain lipophilicity, while the amino group has a certain hydrophilicity. Therefore, in organic solvents such as dichloromethane, chloroform, and acetone, it may have good solubility. Due to the principle of similar miscibility, these organic solvents interact with the lipophilic part of the molecule to help it disperse and dissolve. In polar solvents such as water, the solubility may be limited. Although the amino group can form a hydrogen bond with water, the overall lipophilic group dominates, limiting its solubility in water.
This density is also an important physical property. The density depends on the molecular mass and the way of molecular accumulation. The molecular mass is large and the structure is tight, resulting in a relatively high mass per unit volume. However, the precise density value needs to be determined experimentally, and the density is affected by different crystal forms or molecular arrangements.
In addition, its refractive index reflects the ability of the substance to refract light, which is related to the molecular structure and the distribution of electron clouds. Complex conjugate systems and polar groups make the distribution of electron clouds special, which affects the speed and direction of light propagation. The refractive index has a unique value, which is an important basis for the identification and analysis of this substance.

To prepare diethyl 5- {{ (2E) -3- (4-methoxyphenyl) prop-2-enoyl} amino} -3-methylthiophene-2, 4-dicarboxylate can be obtained as follows.
First take 3-methyl-thiophene-2,4-diformate as the starting material. This raw material is reacted with (2E) -3- (4-methoxyphenyl) propyl-2-enyl chloride in a suitable reaction vessel under the catalytic action of a base. The choice of base is very critical, such as triethylamine, pyridine, etc. can be used as common bases. The function of the base is to capture the hydrogen at the active check point in the 3-methyl-thiophene-2,4-diethyl dicarboxylate molecule to form a nucleophilic reagent, and then react with (2E) -3- (4-methoxyphenyl) propyl-2-enyl chloride.
During the reaction, it is crucial to control the reaction temperature. Generally speaking, low temperature can make the reaction more selective, and the temperature can be maintained at about 0 ° C. After the reaction is initiated, the temperature can be slowly raised to room temperature or moderately increased according to the reaction process to promote the reaction. However, the temperature should not be too high to avoid side reactions. < Br >
The reaction solvent also needs to be carefully selected. Commonly used organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF) can be considered. Among them, dichloromethane is more commonly used because of its good solubility and volatility.
When the reaction is over, conventional separation and purification methods, such as column chromatography, are used. Using silica gel as the stationary phase, a suitable eluent is selected to separate the product and the impurity according to the difference in the partition coefficient between the stationary phase and the mobile phase, so as to obtain pure diethyl 5- {{ (2E) -3- (4-methoxyphenyl) propyl-2-enyl} amino} -3 -methylthiophene-2,4-diethyl dicarboxylate. In this way, the target product can be prepared according to this method.

V-diethyl 5- {{ (2E) -3- (4-methoxyphenyl) prop-2-enoyl} amino} -3-methylthiophene-2, 4-dicarboxylate, is a kind of organic compound. Its application field is quite extensive, in the field of medicinal chemistry, or can be used as a lead compound to help create new drugs. Due to its special molecular structure, it may interact with specific targets in organisms to play a therapeutic effect.
In the field of materials science, such compounds may have unique optical and electrical properties and can be applied to the research and development of organic optoelectronic materials. For example, in the field of organic Light Emitting Diode (OLED), it may be used as a light-emitting layer material to improve the luminous efficiency and stability of devices.
In agricultural chemistry, it may also show potential application value. Or it can be designed as a molecule with biological activity for the development of new pesticides, which have inhibitory or killing effects on pests or pathogens, and are more selective and environmentally friendly than traditional pesticides.
In chemical synthesis research, this compound can be used as a key intermediate to build more complex organic molecular structures, expand the strategies and paths of organic synthesis, and contribute to the development of organic chemistry.

This compound is called diethyl 5- { (E) -3- (4-methoxyphenyl) propane-2-enamido} -3 -methylthiophene-2,4-dicarboxylate. In today's chemical market, although this compound is not a common bulk chemical known to everyone, it is quite valuable in specific fields.
View all pharmaceutical research and development, which may be a key intermediate for the creation of new drugs. Because the functional groups such as thiophene, enamido and ester groups contained in the molecular structure can be chemically modified to meet the needs of specific targets, it may have a chance to emerge in the exploration of new drugs.
In the field of materials science, compounds containing such structures may give materials special optoelectronic properties. For example, in the research of organic Light Emitting Diode (OLED) materials, its unique structure may optimize the luminous efficiency and stability of materials, contributing to the research and development of new display materials.
Although the current market size may be limited, with the deepening of scientific research and the expansion of related industries, its market prospects may gradually expand. With the improvement of synthesis processes, production costs are expected to decrease, thereby enhancing its market competitiveness. Over time, in the field of fine chemical and high-tech materials, it may be able to occupy a place and become a new force driving industrial development.