Chemical Name | diethyl 3-methyl-5-[(morpholin-4-ylacetyl)amino]thiophene-2,4-dicarboxylate |
Molecular Formula | C19H26N2O7S |
Molecular Weight | 426.485 g/mol |
Appearance | Typically a solid (appearance can vary) |
Physical State | Solid (at standard conditions) |
Solubility | Solubility characteristics depend on solvents; may be soluble in some organic solvents |
Melting Point | Data specific to this compound needed for exact value |
Boiling Point | Data specific to this compound needed for exact value |
Density | Data specific to this compound needed for exact value |
Pka | Data specific to this compound needed for exact value |
Logp | Data specific to this compound needed for exact value |
What are the chemical properties of this product diethyl 3-methyl-5- [ (morpholin-4-ylacetyl) amino] thiophene-2,4-dicarboxylate
The chemical properties of diethyl 3-methyl-5- [ (morpholin-4-ylacetyl) amino] thiophene-2,4-dicarboxylate are quite elegant. From the structural point of view, this compound contains a thiophene ring, which is a five-membered heterocyclic ring with certain aromaticity, endowing it with special stability and electron cloud distribution, making this compound different from common straight-chain or other cyclic compounds, showing unique activity in chemical reactions.
It contains an ester group (diethyl... dicarboxylate part), which has hydrolytic properties. Hydrolysis can occur in contact with water or under acid-base catalysis. In an acidic environment, hydrolysis is slow to form carboxylic acids and alcohols; under alkaline conditions, hydrolysis is rapid to form carboxylic salts and alcohols, which is of great significance in organic synthesis and metabolism in vivo.
Furthermore, the amino group (5- [ (morpholin-4-ylacetyl) amino] part) in the molecule is basic, which can react with acids to form salts, enhance the water solubility of compounds, and the amino group acts as an active check point, which can participate in reactions such as nucleophilic substitution, react with electrophilic reagents such as halogenated hydrocarbons, and realize structural modification and derivatization. < Br >
The methyl group on the thiophene ring is the power supply group, which can change the electron cloud density on the ring, affect the regioselectivity of the electrophilic substitution reaction, and make the reaction more likely to occur at the higher electron cloud density position.
In short, this compound is rich in chemical properties due to the interaction of various functional groups, and may have broad application prospects in organic synthesis, drug development and other fields.
What are the main uses of the product diethyl 3-methyl-5- [ (morpholin-4-ylacetyl) amino] thiophene-2,4-dicarboxylate
This substance is called 3-methyl-5- [ (morpholine-4-ylacetyl) amino] thiophene-2,4-dicarboxylate diethyl ester, and it has a wide range of uses. In the field of medicine, it is often used as a key intermediate to help the development of new drugs. Because of its specific chemical structure, it can interact with specific targets in organisms, which is of great significance for the treatment of certain diseases. For example, in the development of some drugs for inflammation or neurological diseases, it can be chemically modified to construct drug molecules with stronger activity and higher specificity.
In the field of organic synthesis, it is an indispensable raw material. With the help of its thiophene ring and many active groups, chemists can use a variety of organic reactions to construct complex and functional organic compounds, laying the foundation for the creation of new organic materials in the field of materials science, such as organic optoelectronic materials, injecting new vitality into the development of this field.
In the process of scientific research and exploration, it is also an important research object. Through in-depth exploration of its reaction characteristics, structure and properties, researchers can deepen their understanding of the basic theory of organic chemistry, expand new methods and new paths of organic synthesis, and contribute to the continuous progress of organic chemistry.
What is the production process of diethyl 3-methyl-5- [ (morpholin-4-ylacetyl) amino] thiophene-2,4-dicarboxylate
The production process of diethyl 3 - methyl - 5 - [ (morpholin - 4 - ylacetyl) amino acid] thiophene - 2,4 - dicarboxylate is an important task in fine chemical synthesis. The preparation method often begins with a specific starting material.
First take a suitable sulfur-containing compound, which may be the foundation for constructing a thiophene ring. To properly react with a methyl-containing compound, appropriate reaction conditions, such as precise control of temperature, pressure and reaction time, are required to effectively combine the two to form a methyl-containing thiophene derivative.
Then, for the carboxylation step of the thiophene ring, a specific carboxylation reagent is often used to introduce a carboxyl group at a specific position of the thiophene ring in a suitable solvent system with the help of a catalyst. This step requires careful regulation of the reaction conditions to prevent side reactions from breeding and reducing the yield. After this, a thiophene compound containing a carboxyl group can be obtained.
Furthermore, the prepared carboxyl-containing thiophene compound is reacted with a reagent containing a morpholin-4-ylacetyl group. The key to this reaction is the condensation of the amino group and the acyl group, and the participation of a coupling reagent is often required to promote the efficient binding of the two to form a crucial amide bond in the target product. This process also needs to pay attention to the optimization of the reaction conditions to ensure the smooth progress of the reaction and obtain a higher purity product.
Ultimately, the product needs to be separated and purified, or column chromatography, recrystallization method, etc., to remove impurities, improve the purity of the product, and achieve the required Quality Standards for production. The entire production process is interlocked, and each step needs to be carefully controlled to obtain high-quality diethyl 3 - methyl - 5 - [ (morpholin - 4 - ylacetyl) amino] thiophene - 2,4 - dicarboxylate.
What is the market price range of the product diethyl 3-methyl-5- [ (morpholin-4-ylacetyl) amino] thiophene-2,4-dicarboxylate?
"Tiangong Kaiwu" is a masterpiece of ancient science and technology in our country, but I have never heard of the book about the market price range of "diethyl 3 - methyl - 5 - [ (morpholin - 4 - ylacetyl) amino] thiophene - 2,4 - dicarboxylate". The name of this compound is complex, and it seems to be a product of modern fine chemistry, which cannot be involved in the era of "Tiangong Kaiwu".
The cover "Tiangong Kaiwu" was written in the Chongzhen period of the Ming Dynasty, when the level of science and technology was very different from today. The book contains mostly the production techniques of agriculture and industry at that time, such as grain cultivation, silk textile, ceramic firing, metal smelting, etc. And this compound, whose structure contains specific organic groups, may require modern chemical synthesis methods. At that time, there was no relevant industrial production, nor market transactions, so there was naturally no market price range to speak of.
If you want to know the market price of this product, you should consult professional chemical product suppliers in today's chemical market, chemical raw material trading platforms or consult professional chemical product suppliers. Its price may be affected by many factors such as raw material cost, synthesis difficulty, market demand, purity requirements, etc., fluctuating. Or due to special uses, it is only circulated in specific scientific research and industrial fields, and the price is more difficult to generalize.
What are the precautions for diethyl 3-methyl-5- [ (morpholin-4-ylacetyl) amino] thiophene-2,4-dicarboxylate during storage and transportation?
The diethyl 3 - methyl - 5 - [ (morpholin - 4 - ylacetyl) amino] thiophene - 2,4 - dicarboxylate is also an organic compound. During storage and transportation, many matters must not be ignored.
First words storage, this material should be placed in a cool and dry place, away from direct sunlight. Cover the heat and light of sunlight, or cause structural variation of compounds, damaging their properties. And it must be kept away from fires and heat sources to prevent the risk of fire and explosion. Because of its flammability, in case of open flames and hot topics, it may be unpredictable.
Furthermore, where it is stored, air should be circulated. If the air is blocked, the gas emitted by the compound will accumulate, which may pose a safety hazard. It should also be stored separately from oxidizing agents, acids, alkalis, etc., to cover the encounter between such substances and the compound, which is prone to chemical reactions and deterioration.
As for transportation, it is necessary to ensure that the container is well sealed and there is no risk of leakage. If there is a leak, it will not only damage the compound, but also pollute the environment and endanger people and animals. Transportation vehicles should also be equipped with corresponding fire equipment to prevent fires on the way. During transportation, the driving should be stable, avoid sudden braking and sharp turns, and avoid collision and damage to the container.
In short, when storing and transporting diethyl 3 - methyl - 5 - [ (morpholin - 4 - ylacetyl) amino] thiophene - 2,4 - dicarboxylate, it is necessary to exercise caution and follow safety regulations to ensure its quality and transportation safety, avoid accidents, and protect the environment and personal safety.