diethyl 3-methyl-5-{[(2E)-3-(thiophen-2-yl)prop-2-enoyl]amino}thiophene-2,4-dicarboxylate

This is the question of the compound "diethyl 3-methyl-5- {[ (2E) -3- (thiophen-2-yl) prop-2-enoyl] amino} thiophene-2,4-dicarboxylate". I want to know its chemical structure. Let me explain in detail.
In the structure of this compound, the thiophene ring is the key part. On the thiophene ring, there is a methyl group at 3 positions, which adds its structural properties. At 5 positions, there is a complex side chain. The side chain starts with an amino group, and the amino group is connected to an alkenyl group. In this alkenyl group, the double bond is in the (E) configuration. This configuration determines its spatial structure. The alkenyl group is connected with a thiophene ring at one end and a thiophene-2-group at the other end. The presence of another thiophene ring enriches its conjugate system. Furthermore, the 2nd and 4th positions of the thiophene ring are respectively connected with ethyl ester groups. Ethyl ester groups are common functional groups, which affect the physical and chemical properties of the compound.
Overall, the structure of this compound integrates a variety of functional groups, and the interaction of each functional group determines its unique chemical and physical properties. The complexity of its structure, the delicacy of chemistry, and the synergy of all parts make this compound have special reactivity and potential application value.

This compound is called diethyl 3-methyl-5- {[ (2E) -3 - (thiophene-2-yl) propyl-2-enyl] amino} thiophene-2,4-dicarboxylic acid ester. Its main uses are quite extensive, in the field of medicine, or it can act as a drug intermediate. Through specific chemical reactions, modified or combined with other molecules, new drugs with specific pharmacological activities can be created, opening up new paths for the treatment of diseases. In the field of organic synthetic chemistry, it can be used as a key synthetic building block, with its unique molecular structure, to help build more complex organic compounds for the exploration of new materials or organic molecules with special properties. In the field of materials science, it may become an important raw material for the preparation of functional materials, such as the development of materials with specific optical and electrical properties, and contribute to the development of electronic devices, optical devices, etc. Its application in these fields seems to build an indispensable bridge between many scientific research and practical applications, driving the continuous development of various fields.

To obtain this substance, namely diethyl 3-methyl-5- {[ (2E) -3- (thiophen-2-yl) prop-2-enoyl] amino} thiophene-2,4-dicarboxylate, the synthesis method is quite complicated.
First of all, it is necessary to select suitable starting materials, such as compounds containing thiophene structure, and substances with functional groups such as alkenyl groups and amino groups. The starting materials are carefully treated to ensure their purity and activity are suitable for the reaction.
Then, the condensation reaction is carried out. In a specific reaction vessel, add the starting materials and dissolve them in a suitable organic solvent to create a homogeneous reaction environment. Then add an appropriate amount of catalyst, which must be able to effectively promote the condensation reaction, or be an organic base catalyst to promote the condensation of alkenyl groups and amino groups to form key amide bonds. The reaction temperature and time also need to be precisely controlled. If the temperature is too high or too low, if the time is too long or too short, it can affect the yield and purity of the reaction.
Then, the reaction product is separated and purified. The method of extraction can be used to take advantage of the difference in the solubility of different solvents to the product and impurities. Then column chromatography is used to further purify the product and impurities according to the different distribution coefficients between the stationary phase and the mobile phase, and obtain a purified target product.
The whole process of synthesis is crucial to the control of the reaction conditions, and modern analytical methods, such as nuclear magnetic resonance and mass spectrometry, are required to monitor the reaction process and product structure in real time to ensure the smooth synthesis and obtain high-purity diethyl 3-methyl-5- {[ (2E) -3- (thiophen-2-yl) prop-2-enoyl] amino} thiophene-2,4-dicarboxylate.

This compound is called diethyl 3-methyl-5- {[ (2E) -3 - (thiophene-2-yl) propylene-2-enoyl] amino} thiophene-2,4-dicarboxylate. Its physical and chemical properties are as follows:
In appearance, it is often in a solid state. Due to the presence of various groups in the molecular structure, the intermolecular interaction is complex, and it tends to form a solid aggregate state. The color may be white to light yellow, which is due to the characteristics of intramolecular electron transition. Some conjugated structures have weak absorption of specific wavelengths of light, showing this color range.
In terms of solubility, it is difficult to dissolve in water. Water is a highly polar solvent. Although the compound contains polar groups such as carboxyl ester groups, the non-polar parts such as thiophenyl, methyl and alkenyl groups account for a large proportion. According to the principle of similarity dissolution, its polarity is different from water, and it is not easy to disperse and dissolve in water. However, it is soluble in common organic solvents, such as halogenated hydrocarbons such as dichloromethane and chloroform, as well as polar organic solvents such as acetonitrile and acetone. Halogenated hydrocarbons such as dichloromethane can interact with compound molecules through van der Waals forces; the polarity of acetonitrile and acetone matches the partial polar groups of the compound, which can form a certain intermolecular force with the compound to promote dissolution.
Melting point is affected by intermolecular force and structural regularity. There are conjugated systems, hydrogen bonds and other functions in the molecule, which make the intermolecular bonding close, usually with a high melting point. The specific value needs to be accurately determined experimentally. It is estimated that in a higher temperature range, due to the synergistic effect of the conjugated structure and various groups, the intermolecular force is enhanced, and high energy is required to destroy the lattice and melt.
In terms of stability, it is relatively stable under conventional environmental conditions. However, due to the presence of carbon-carbon double bonds, it is easily affected by light and high temperature, and photochemical reactions or heat-induced addition and polymerization reactions occur. Although the thiophene ring is relatively stable, it can change the ring structure or ring opening and substitution under extreme conditions such as strong oxidants, strong acids and bases. Its ester group will undergo hydrolysis reaction under acid or base catalysis, and the hydrolysis under acidic conditions is relatively mild, resulting in corresponding carboxylic acids and alcohols; under alkaline conditions, the hydrolysis is more thorough, resulting in carboxylic salts and alcohols.

I have not obtained the exact number of "diethyl 3-methyl-5- {[ (2E) -3- (thiophen-2-yl) prop-2-enoyl] amino} thiophene-2,4-dicarboxylate" in the price range on the market. The price of this compound may vary greatly depending on its use, purity, supply and demand.
If it is a high-purity reagent commonly used in scientific research and used for precise laboratory experiments, its price may be high. Due to the preparation of fine processes, limited output, or specific equipment and technology, the purity can reach 98 or even 99 or more, and the price per gram may be hundreds or even thousands of yuan.
If used in industrial production, the purity requirements are slightly lower, the output is larger, and the price per kilogram may be several thousand yuan according to market supply and demand and production costs.
However, to know the exact price range, you need to check the chemical product trading platform, the website of the reagent supplier, or consult the industry and relevant manufacturers. This can be changed to the exact price range due to the current market conditions.