Benzothiophene, 6-methyl

6-Methylmercaptopurine is mainly used in the field of medicine. It is a purine analogue and has made outstanding contributions to the field of anti-metabolic drugs.
This drug can interfere with nucleic acid synthesis in vivo. When cells proliferate, nucleic acid synthesis is crucial. 6-Methylmercaptopurine is metabolically transformed to generate corresponding nucleotide analogs. These analogs can be mixed into the nucleic acid synthesis process, but cannot perform functions like normal nucleotides, thereby hindering nucleic acid synthesis and inhibiting cell proliferation.
Tumor cells proliferate rapidly and have a high demand for nucleic acid synthesis. 6-Methylmercaptopurine can effectively inhibit the growth and proliferation of tumor cells by interfering with nucleic acid synthesis. It plays a key role in tumor chemotherapy and is often used in the treatment of diseases such as acute leukemia.
In addition, it is also used in the treatment of autoimmune diseases. Autoimmune diseases are caused by the body's immune system mistakenly attacking its own tissues, causing excessive proliferation and activation of immune cells. 6-Methylmercaptopurine inhibits the proliferation of immune cells, regulates the immune response, and relieves the symptoms of autoimmune diseases, such as the treatment of rheumatoid arthritis.
In summary, the main uses of 6-methylmercaptopurine are anti-tumor and treatment of autoimmune diseases. By interfering with nucleic acid synthesis, they can bring hope for recovery to many patients.

6-Methylpurinodione, also known as caffeine, is a common alkaloid that is widely found in tea, coffee, cocoa and other plants. Its physical properties are as follows:
Looking at its morphology, under room temperature and pressure, 6-methylpurinodione is a white needle-like crystal with a clean and regular appearance and a shiny appearance. The morphology of this crystal is easy to identify and distinguish, and it is unique among many substances.
Smell its smell, which is almost odorless and does not have an irritating or special smell. This property makes it easy to identify and distinguish when it is incorporated into drinks or other substances, and it will not interfere with the overall flavor due to its own smell, so it can be widely used in various foods and beverages.
Taste its taste, it has a bitter taste, but the bitter taste is not unacceptable. On the contrary, when in moderation, it can add a unique flavor level to coffee, tea and other beverages, which has become one of the reasons why many beverage lovers love it.
In terms of its solubility, 6-methylpurinodione is soluble in water, but its solubility is limited. In hot water, the dissolution effect is better, which is why when brewing coffee or tea, hot water can extract the caffeine component more effectively. At the same time, it can also dissolve in organic solvents such as ethanol and chloroform. This solubility makes it have certain application value in chemical, pharmaceutical and other fields. It can be extracted and separated with the help of organic solvents.
The melting point of 6-methylpurinodione is about 235-238 ° C. The characteristics of the melting point can be used as an important basis for identifying the purity of the substance. The higher the purity, the closer the melting point is to the standard value, and the smaller the fluctuation range.
In summary, the physical properties of 6-methylpurinodione, such as white needle-like crystalline form, near-odorless, bitter taste, specific solubility, and melting point, make it play an important role in food, beverage, medicine, and other fields, bringing many conveniences and benefits to human life and production.

6-Methylpurine imidazole is an organic compound with unique chemical properties and many wonderful properties.
From the structural point of view, this compound is formed by the fusion of purine and imidazole ring, and the presence of 6-methyl adds uniqueness to its structure. This structure gives it a specific chemical activity and reaction tendency.
In terms of acidity and alkalinity, because of its nitrogen-containing atoms, it can exhibit a certain alkalinity. The lone pair electrons on the nitrogen atom can accept protons, and in an acidic environment, or can form cations and participate in ionic reactions.
Discusses stability, and the aromatic ring structure in this compound gives it a certain stability. The aromatic system has resonance stabilization energy, which makes the molecular structure more stable and difficult to decompose spontaneously. However, under certain conditions, such as high temperature, strong acid-base or strong oxidizing agent, reducing agent, the stability may be affected.
In terms of chemical reactivity, the methyl group of 6-methyl can participate in a variety of reactions. For example, the hydrogen atom of the methyl group may be substituted. Under suitable reagents and conditions, a halogenated reaction occurs, and a halogen atom replaces the hydrogen atom on the methyl group. And the nitrogen atom on the ring may also be a nucleophilic reaction check point, reacting with the electrophilic reagent to change the molecular structure.
In addition, the compound may exhibit a selective reaction to some specific reagents. In the field of organic synthesis, its unique chemical properties may be used to prepare more complex and functional organic compounds by designing specific reaction routes.
In summary, the unique structure of 6-methylpurine imidazoline presents diverse chemical properties and has potential application value in organic chemistry research and related fields. It is worth exploring more properties and reaction laws.

There are various ways to synthesize 6-methylpurine imidazole. The following is described in detail by Jun.
First, it can be started from imidazole compounds containing specific substituents. Take an imidazole derivative, which has a suitable activity check point in its structure, and introduce a methylpurine group under specific reaction conditions. For example, first place the imidazole derivative in a suitable organic solvent, such as dichloromethane or N, N-dimethylformamide, and add an appropriate amount of base, such as potassium carbonate or triethylamine, to regulate the pH of the reaction environment. Subsequently, the halogen containing the methylpurine structure is slowly added dropwise, and the halogen atoms in the halogen have good exoticism, which can undergo nucleophilic substitution reaction with the active check point of the imidazole derivative. In this process, the base can promote the nucleophilicity of the active check point of the imidazole derivative and speed up the reaction process. After the reaction is completed, the target product 6-methylpurine imidazole can be obtained by separation and purification methods such as extraction and column chromatography.
Second, the purine compound can also be started from the purine compound. Select a suitable purine derivative with a modifiable group at a specific position. React the purine derivative with the imidazole-containing precursor in a suitable reaction system. For example, in the acetic anhydride-sodium acetate buffer system, the purine derivative and the imidazole precursor undergo condensation reaction under heating conditions. Acetic anhydride provides an acetylation environment, and sodium acetate maintains the weak acidity of the system, which is conducive to the reaction. By controlling the reaction temperature and time, key chemical bonds such as carbon-carbon bonds or carbon-nitrogen bonds are formed between the two molecules, and the molecular skeleton of 6-methylpurine-imidazole is gradually constructed. After the reaction is completed, the purified product is obtained by recrystallization, distillation, etc.
Third, a multi-step tandem reaction strategy can also be used. First, the imidazole fragment and the methylpurine fragment were constructed from simple starting materials, such as nitrogen-containing heterocyclic small molecules and halogenated hydrocarbons, through multi-step reaction. After that, the reaction conditions were cleverly designed, so that the two fragments were coupled in the same reactor to directly generate 6-methylpurine imidazole. The advantage of this method is that the reaction process can be finely regulated, and the separation steps of intermediates can be reduced, which improves the reaction efficiency and atomic economy. However, this strategy requires more stringent reaction conditions, and requires precise control of parameters such as temperature, reactant ratio, and reaction time of each step of the reaction.

6-Methylmercaptopurine is an important drug, and its market price range often varies due to factors such as quality, source, and transaction scale.
In the market, if it is ordinary quality 6-methylmercaptopurine, when traded in batches, the price per gram may be around tens to hundreds of yuan. However, if it is a high-purity, pharmaceutical-grade product, the price should be higher. Pharmaceutical-grade 6-methylmercaptopurine, due to strict purity requirements and complicated preparation processes, may cost hundreds of yuan per gram.
If the transaction scale is small, such as a small amount purchased by the laboratory, the price will also be higher. For large-scale commercial purchases, unit prices may be reduced due to economies of scale.
And market prices are also influenced by supply and demand. If the market demand is strong and the supply is limited, the price may rise; conversely, if the supply is sufficient and the demand is flat, the price may stabilize or even decline. Therefore, the exact price of 6-methylmercaptopurine is difficult to generalize and depends on the specific transaction situation.