6-METHYLBENZOTHIOPHENE

6-Methylbenzothiophene has a unique chemical structure. Benzothiophene is a heterocyclic compound formed by fusing a benzene ring with a thiophene ring. The thiophene ring is a sulfur-containing five-membered heterocyclic ring and has aromatic properties; the benzene ring is a common six-membered carbon ring and also has aromatic properties. After fusing the two, a stable conjugated system is formed, which endows benzothiophene with unique chemical activity and physical properties.
In 6-methylbenzothiophene, the expression "6-methyl" means that the methyl (-CH) substituent is attached to the No. 6 position of the parent structure of benzothiophene. The so-called No. 6 position depends on a specific numbering rule. Usually, starting from the common carbon atom where the thiophene ring fuses with the benzene ring, the benzene ring and the thiophene ring are numbered in sequence. In this way, the 6-position is a specific position, and the methyl group is connected to it, changing the electron cloud distribution and spatial structure of the molecule. The introduction of methyl group makes the chemical properties of 6-methyl benzothiophene different from that of the benzothiophene parent group. Methyl group is the power supply radical, which can increase the electron cloud density of the benzothiophene ring and affect the activity and selectivity of its electrophilic substitution reaction. In space, the presence of methyl group may also interfere with the interaction between molecules, affecting the melting point, boiling point and other physical properties of the compound. Due to its unique chemical structure, it has potential applications in many fields such as organic synthesis, materials science, and medicinal chemistry.

6-Methylbenzothiophene is a class of organic compounds. It has a wide range of uses and is important in various fields.
In the field of medicinal chemistry, it is often a key intermediate for the synthesis of drugs. Due to the unique structure of benzothiophene, the synthesized drugs are endowed with specific biological activities. For example, some drugs with anti-tumor activity, 6-methylbenzothiophene can be chemically modified and introduced into drug molecules. With its structural properties, it binds to specific targets in tumor cells, interfering with the growth and proliferation process of tumor cells, and then achieves the effect of treating tumors.
In the field of materials science, 6-methylbenzothiophene also made significant contributions. First, in the field of organic optoelectronic materials, it can be used as a building unit to synthesize polymers with excellent optoelectronic properties. Such polymers are widely used in organic Light Emitting Diodes (OLEDs), organic solar cells and other devices. In OLEDs, it can improve the luminous efficiency and stability of the device; in organic solar cells, it can enhance the material's ability to absorb light and charge transport, thereby improving the photoelectric conversion efficiency of the battery. Second, in terms of liquid crystal materials, compounds containing 6-methylbenzothiophene structure can exhibit a unique liquid crystal phase state, which is applied to display technology to help improve the display effect and response speed.
In the field of pesticide chemistry, 6-methylbenzothiophene can be used as a lead compound to create new pesticides through structural optimization and derivatization. Such pesticides can target specific pests or bacteria, exhibit high-efficiency insecticidal and bactericidal activities, and are relatively friendly to the environment. They can effectively protect the growth of crops and reduce the harm of pests and diseases to agricultural production.
In addition, in the field of fine chemicals, 6-methylbenzothiophene can be used to synthesize fine chemicals such as special fragrances and dyes. With its unique structure, it gives fragrances a special aroma, or makes dyes have better dyeing performance and color fastness. Therefore, the unique structure of 6-methylbenzothiophene plays an indispensable role in many fields such as medicine, materials, pesticides and fine chemicals, and has made outstanding contributions to the development of various fields.

6-Methylbenzothiophene is one of the organic compounds. Its physical properties are quite unique, and it plays an important role in chemical research and industrial applications.
First of all, its appearance, 6-methylbenzothiophene is mostly white to light yellow crystalline powder under normal conditions. This form is easy to observe and process. In many experiments and production processes, the characteristics of this powder make the operation more convenient, and it is also conducive to its mixing and reaction with other substances.
Furthermore, the melting point is a key indicator to measure its physical properties. The melting point of 6-methylbenzothiophene is about 33-35 ° C. The specific value of the melting point not only reflects the stability of the internal structure of the substance and the strength of the intermolecular force, but also has great significance in practical applications. For example, in the process of material synthesis, separation and purification, the reaction temperature and conditions can be precisely controlled according to the melting point, so as to achieve the expected chemical change and material separation effect.
When talking about the boiling point, it is about 265-267 ° C. The level of boiling point is related to the volatility and stability of the substance in high temperature environment. In the distillation and rectification processes of chemical production, the boiling point is a key parameter, according to which the mixture can be effectively separated to obtain high-purity 6-methylbenzothiophene.
6-methylbenzothiophene is insoluble in water, but soluble in organic solvents such as ethanol, ether, chloroform, etc. This solubility characteristic is due to the interaction between the polar and non-polar parts of its molecular structure. In the field of organic synthesis, its solubility in different solvents can be used to select a suitable reaction medium to promote the progress of chemical reactions; in the analysis and detection work, the appropriate extractant can be selected according to its solubility to achieve effective extraction and enrichment of 6-methylbenzothiophene in the sample.
In addition, its density is also an important physical property. Although the specific value may vary slightly due to measurement conditions, its density is relatively stable. Density information is indispensable for mass and volume conversion, material ratio, and chemical equipment design.
In summary, the physical properties of 6-methylbenzothiophene, such as appearance, melting point, boiling point, solubility, and density, are related and affect each other. Only by deeply understanding and grasping these properties can this compound be better used in chemical research, industrial production, and related fields to achieve the expected scientific goals and economic benefits.

There are many methods for synthesizing 6-methylbenzothiophene. One method can also be started from o-methylthiophenol and acrylate. First, the Michael addition reaction of o-methylthiophenol and acrylate is performed to obtain an intermediate product. This reaction requires stirring the reaction number in a suitable solvent, such as toluene, and a base as a catalyst, such as potassium carbonate, at a suitable temperature, about 60-80 degrees Celsius, so that the reaction is sufficient. The resulting intermediate product is then cyclized within the molecule. This step often requires heating, at a high temperature of about 180-200 degrees Celsius, under the protection of an inert gas, such as nitrogen, 6-methylbenzothiophene can be obtained. < Br >
Another method uses o-bromotoluene and thiourea as raw materials. Schilling o-bromotoluene and thiourea react in an alkaline environment, such as sodium hydroxide solution, in an ethanol solvent, heated to reflux, about 80-100 degrees Celsius, to form a sulfur-containing intermediate. Subsequently, the intermediate is acidified to cyclize to 6-methylbenzothiophene. During the acidification process, dilute hydrochloric acid is used to adjust the acidity and control the reaction conditions to obtain the target product.
Another method uses o-methylbenzoic acid and sulfur as raw materials. First, mix o-toluic acid with sulfur, add an appropriate amount of catalyst, such as iodine, in a high boiling point solvent, such as quinoline, heat to about 200-250 degrees Celsius, and after complex rearrangement, cyclization and other series of reactions, 6-methylbenzothiophene is finally obtained. These methods have their own advantages and disadvantages, and need to be selected according to the actual situation, such as raw material availability, cost, product purity and other factors.

What I am asking you is to inquire about the price range of 6-methylbenzothiophene in the market. However, the price of this chemical often changes for many reasons, and it is difficult to determine the exact price.
The change in its price varies primarily due to purity. If the purity is extremely high, it is almost flawless, and the price is high; and if the purity is slightly lower, the price may be slightly lower. And different suppliers, because of their different costs and operating methods, charge different prices. Large merchants may be able to supply it at a more appropriate price due to the benefit of scale; small merchants may be constrained by cost, and the price is slightly higher.
Furthermore, the state of market supply and demand is also the key. If there are many people who want it, and there are few people who supply it, the price will rise; on the contrary, if the supply exceeds the demand, the price will fall. In addition, the price of raw materials required for production, the complexity of the manufacturing process, and the distance and difficulty of transportation can all affect its final selling price.
According to past conditions, the price of 6-methylbenzothiophene ranges from tens to hundreds of yuan per gram. However, this is only a rough estimate, and the actual price is subject to the current market, specific suppliers, and the general situation at the time of transaction. To know the exact price, you must consult the chemical raw material supplier, or check in detail on the relevant chemical product trading platform.