6 Hydroxy 2 4 Hydroxyphenyl Benzo B Thiophene
quinoline thiophene imidazole thiazole

6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene

Taiy Chemical

    Specifications

    HS Code

    460039

    Chemical Formula C14H10O3S
    Molecular Weight 258.297 g/mol
    Appearance Solid (usually)
    Physical State At Room Temp Solid
    Melting Point Data may vary, needs experimental determination
    Boiling Point Data may vary, needs experimental determination
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO
    Stability Stable under normal conditions
    Pka Data may vary, needs experimental determination
    Color Typically colorless to off - white

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    General Information
    Where to Buy 6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene in China?
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    Frequently Asked Questions

    As a leading 6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 6-hydroxy-2- (4-hydroxyphenyl) benzo [b] thiophene?
    6-Hydroxy-2 - (4-hydroxyphenyl) benzo [b] thiophene is an organic compound with a wide range of uses and important value in many fields.
    In the field of medicine, this compound has shown potential medicinal efficacy. Studies have shown that it may have some biological activity and can affect specific biochemical processes. Some studies suggest that it may regulate the physiological functions of certain cells in the human body, such as its effect on cell signaling pathways, which may in turn help to develop therapeutic drugs for specific diseases. For example, in the research and development of anti-cancer drugs, it may be used as a lead compound to develop new anti-cancer drugs that inhibit the growth and proliferation of cancer cells through structural modification and optimization; in the development of drugs for the treatment of nervous system diseases, it may also play an active role by regulating the function of nerve cells.
    In the field of materials science, 6-hydroxy-2 - (4-hydroxyphenyl) benzo [b] thiophene also has unique uses. Due to its special molecular structure, it is endowed with some unique physical and chemical properties, such as specific optical and electrical properties. Based on this, it can be used to prepare new functional materials. In the field of organic optoelectronic materials, it may be used as a key component in the manufacture of organic Light Emitting Diodes (OLEDs), organic solar cells and other devices. Due to its special structure, it can affect the electron transport and luminescence properties of materials, which helps to improve the performance and efficiency of these devices and promote the development of optoelectronic materials technology.
    In the field of chemical synthesis, 6-hydroxy-2 - (4-hydroxyphenyl) benzo [b] thiophene is often used as an important intermediate. With the active groups in its structure, it can be further derived through various chemical reactions. Chemists can use these active checking points to introduce different functional groups to synthesize a series of novel compounds with diverse structures and functions, providing a rich material basis for the development of organic synthetic chemistry and expanding the types and functions of organic compounds.
    What are the physical properties of 6-hydroxy-2- (4-hydroxyphenyl) benzo [b] thiophene
    6 - hydroxy - 2 - (4 - hydroxyphenyl) benzo [b] thiophene is a kind of organic compound. Its physical properties are quite specific, with specific properties, melting point, boiling point and solubility, etc., which have attracted much attention in the field of chemistry.
    Looking at its properties, under normal conditions, it may be a crystalline solid, white or quasi-white, fine in quality and with a certain luster. The melting point of this compound is very critical, and it has been experimentally determined to be about [X] ° C. The melting point is the temperature at which the substance changes from solid to liquid, and this value reflects the strength of the intermolecular force. A higher melting point indicates that the intermolecular attractive force is large and the structure is relatively stable. The boiling point of
    is also one of the important physical properties. It has been calculated that its boiling point is about [Y] ° C. The boiling point is the temperature at which the saturated vapor pressure of a liquid is equal to the outside atmospheric pressure. The boiling point is related to the size, shape and intermolecular forces of the molecules. A higher boiling point indicates a strong interaction between molecules, or due to factors such as hydrogen bonds and van der Waals forces.
    In terms of solubility, 6-hydroxy-2- (4-hydroxyphenyl) benzo [b] thiophene exhibits unique solubility properties in organic solvents. It has a certain solubility in common organic solvents such as ethanol and dichloromethane. Ethanol, a polar organic solvent, can form hydrogen bonds and other interactions with the molecules of the compound to promote dissolution. In water, its solubility is relatively low, due to the polarity of water and the structure of the compound. The polarity of water is stronger, and although this compound contains hydroxyl groups, it can form hydrogen bonds with water, but the hydrophobic part of the overall structure limits its dissolution in water.
    In addition, the physical properties such as density and refractive index of the compound also affect its chemical behavior and application. Density is related to the mass per unit volume of a substance, and refractive index reflects the characteristics of light propagation in it. The various physical properties are interrelated and jointly determine the application potential of 6-hydroxy-2 - (4-hydroxyphenyl) benzo [b] thiophene in chemical reactions, material preparation and other fields.
    What is the synthesis method of 6-hydroxy-2- (4-hydroxyphenyl) benzo [b] thiophene
    The synthesis of 6-hydroxy-2- (4-hydroxyphenyl) benzo [b] thiophene is an important research in the field of organic synthesis. This compound has a unique structure and potential application value, and the synthesis process requires delicate design and careful operation.
    To synthesize this compound, benzothiophene derivatives containing corresponding substituents are often used as starting materials. First, the hydroxyl group can be introduced at a specific position in the benzothiophene ring by means of an electrophilic substitution reaction. This step requires the selection of suitable electrophilic reagents and reaction conditions to ensure the selectivity of the reaction check point. For example, using phenolic compounds as substrates, under mild acidic or basic conditions, reacting with electrophilic agents such as halogenated hydrocarbons or acyl halides can introduce hydroxyl groups into target sites.
    Furthermore, construct a 4-hydroxyphenyl moiety and connect it to the parent benzothiophene. Transition metal-catalyzed coupling reactions such as Suzuki coupling, Stille coupling, etc. Taking Suzuki coupling as an example, a 4-hydroxyphenyl derivative containing borate ester or boric acid is first prepared, and the halogenated benzothiophene derivative is reacted with the halogenated benzothiophene in the presence of a palladium catalyst, a base, and a suitable solvent. The reaction conditions need to be finely regulated, and the temperature, catalyst dosage, alkali type and dosage will all affect the reaction efficiency and selectivity.
    After the reaction is completed, the product needs to be separated and purified. Column chromatography is commonly used to select the appropriate stationary phase and mobile phase according to the polarity difference between the product and the impurity to achieve effective separation of the product. Recrystallization can also be used to select a suitable solvent. By controlling the temperature and concentration, the product can be crystallized and precipitated to achieve the purpose of purification.
    Synthesis of 6-hydroxy-2- (4-hydroxyphenyl) benzo [b] thiophene requires multi-step reaction coordination, and precise control of each step conditions, in order to obtain high-purity target products, which lays the foundation for its subsequent application research.
    What is the price range of 6-hydroxy-2- (4-hydroxyphenyl) benzo [b] thiophene in the market?
    I don't know the price range of "6-hydroxy-2 - (4-hydroxyphenyl) benzo [b] thiophene" in the market. This is a relatively uncommon chemical substance, and its price is determined by many factors.
    First, the purity has a great impact. If the purity is extremely high, it is suitable for high-end scientific research, pharmaceutical research and development and other precision fields, and the price must be high; if the purity is slightly lower, it is only for general research or industrial preliminary application, and the price should be relatively low.
    Second, the market supply and demand relationship is also the key. If many scientific research institutions and pharmaceutical companies have strong demand for it and limited supply, the price will rise; conversely, if the demand is weak and the supply is sufficient, the price will fall.
    Third, the difficulty and cost of preparation are related to price. If the synthesis of this substance requires complex processes, expensive raw materials and special equipment, the high cost will also be high; if the preparation is relatively simple, the cost is controllable, and the price may be close to the people.
    Fourth, different suppliers have different pricing strategies. Large and well-known suppliers may have higher prices due to their brand, quality control and after-sales advantages; small suppliers may have preferential prices in order to compete for market share.
    To know the exact price range, you should consult chemical reagent suppliers, chemical product trading platforms, or industry insiders in relevant professional forums to obtain accurate information.
    What are the safety and toxicity of 6-hydroxy-2- (4-hydroxyphenyl) benzo [b] thiophene?
    6-Hydroxy-2 - (4-hydroxyphenyl) benzo [b] thiophene, the study of its safety and toxicity is related to the characteristics of the substance and the safety of its use.
    To observe the safety of this compound, when observing its stability in various environments. If it can keep its chemical structure unchanged at room temperature and humidity, or when exposed to light and heat, it has good stability, which is the basis for safety. And if it does not react violently in different media, such as water and organic solvents, and does not generate harmful by-products, it is safe.
    When it comes to toxicity, the first thing to look at is its effect on organisms. At the cellular level, if it does not cause apoptosis, mutation, or does not significantly interfere with cell metabolism and proliferation, the toxicity is minimal. In animal experiments, observe whether there are adverse reactions, such as abnormal behavior, organ damage, and changes in physiological indicators, after oral, percutaneous, or inhalation. If after oral ingestion, the animal does not show vomiting, diarrhea, and malaise, and the pathological examination of the organs shows no signs of damage, the toxicity is low.
    To determine its safety and toxicity, theoretical inference alone is not enough. Rigorous experiments, controlled and variable conditions, and multiple tests are required to prove the data. Only by conducting analysis and testing by professional personnel in accordance with scientific methods can we obtain an accurate conclusion, determine whether it is suitable for use in medicine, chemical industry, etc., and ensure the safety of people and the environment.