5-(methylsulfanyl)thiophene-2-carbaldehyde

5- (methylthiophene) thiophene-2-formaldehyde, this is an organic compound. Looking at its structure, it contains a thiophene ring with a 5-position methylthiophene group and a 2-position aldehyde group on the ring. Its chemical properties are interesting and unique.
Let's talk about the aldehyde group first, which is an active functional group. It has typical aldehyde properties and can undergo oxidation reactions. In case of weak oxidants, such as Torun reagent, it can be oxidized to carboxyl groups to form 5- (methylthiophene) thiophene-2-formic acid. This process is like a delicate "chemical transformation", as if the compound exhibits its own wonderful ability to transform under specific conditions. In case of strong oxidants, such as potassium permanganate, it can also be oxidized, and the degree of reaction is deeper, and the structure will be further changed, just like the compound undergoes profound changes in the intense chemical reaction environment.
The aldehyde group can also undergo a reduction reaction. With hydrogen as the reducing agent, under the action of a suitable catalyst, the aldehyde group will be reduced to a hydroxyl group to obtain 5- (methylthio) thiophene-2-methanol, just like the compound completes the role transition from aldehyde to alcohol on the "stage" of chemical reactions.
Furthermore, the aldehyde group can undergo a nucleophilic addition reaction. Under the catalysis of acid with alcohols, acetals will be formed, which will build a new structure for organic synthesis, as if adding a new "structure" to the compound and enriching its chemical form.
As for the methyl-sulfur group, its sulfur atom has a lone pair of electrons, which can show a certain nucleophilicity. In a suitable reaction system, it can participate in nucleophilic substitution reactions and react with substrates such as halogenated hydrocarbons, so that the structure of the compound can be expanded, just like adding bricks to the "building" of the compound, deriving more kinds of organic compounds, which is of great significance in the field of organic synthesis and provides the possibility for the creation of diverse organic substances.

5- (methylthiophene) thiophene-2-formaldehyde has a wide range of uses and is useful in many fields.
First, in the field of organic synthesis, this is a crucial intermediate. It can combine with other compounds through various chemical reactions, and then build complex organic molecular structures. For example, with compounds containing active hydrogen, according to a specific reaction mechanism, new thiophene derivatives can be generated. Such derivatives may have unique biological activities in drug research and development, or can lay the foundation for the creation of new drugs.
Second, in the field of materials science, it is also indispensable. With this as a raw material, after specific processing, materials with special properties can be prepared. Or because of its molecular structure characteristics, the prepared materials perform well in optoelectronic properties. For example, when applied to organic photoconductors, it can improve the electrical conductivity of materials. In optoelectronic devices, such as organic Light Emitting Diode (OLED) and other fields, it can improve the performance and efficiency of devices.
Third, in the fragrance industry, 5- (methylthio) thiophene-2-formaldehyde can be used as a fragrance component due to its unique odor characteristics. It can add a unique flavor to the fragrance formula. After formulation, it can be used to prepare special flavor edible fragrances, or used to prepare day fragrances with unique aromas, such as perfumes, air fresheners, etc., to meet consumers' demand for unique fragrances.

The synthesis of 5- (methylthiophene) thiophene-2-formaldehyde is an important topic in organic synthetic chemistry. The synthesis method often relies on various organic reactions and exquisite design.
First, or thiophene derivatives can be borrowed as starting materials. With suitable thiophene, methylthiophene and aldehyde groups are introduced at specific positions. Thiophene can be halogenated at specific locations through a halogenation reaction to obtain halogenated thiophene. If bromine or chlorine is used, under appropriate reaction conditions, when light or catalyst is present, the thiophene is halogenated to produce halogenated thiophene products.
Then, methylthiophene is introduced. The nucleophilic substitution reaction can be used to react with thiophenes such as sodium methyl mercaptan with halogenated thiophenes. This reaction is carried out in suitable solvents, such as polar aprotic solvents, such as dimethyl sulfoxide (DMSO) or N, N-dimethylformamide (DMF). At moderate temperatures, the halogen atom is substituted with methylthio to obtain thiophene derivatives containing methylthio groups.
As for the introduction of aldehyde groups, there are also many methods. First, the Vilsmeier-Haack reaction can be used. Mix thiophene derivatives containing methylthio groups with N, N-dimethylformamide (DMF) and phosphorus oxychloride (POCl 🥰). DMF is first reacted with POCl to form an active intermediate. This intermediate reacts with thiophene derivatives to introduce an aldehyde group at a specific position of thiophene, resulting in 5- (methylthio) thiophene-2-formaldehyde.
Or, the aldehyde group is introduced first, and then the methylthio group is introduced. The synthesis of the target product can also be achieved by using thiophene-2-formaldehyde as the starting material, first halogenated, and then nucleophilic substitution with methylthiol salt. However, in all synthesis methods, it is necessary to pay attention to the precise control of the reaction conditions, such as temperature, solvent, and ratio of reactants, to avoid side reactions and improve the yield and purity of the product.

5- (methylthiophene) thiophene-2 -formaldehyde is an organic compound. During storage, the following things should be paid attention to:
First, it is related to the temperature and humidity of the storage environment. This compound is quite sensitive to temperature and humidity, and high temperature or high humidity environment is easy to cause it to deteriorate. It should be stored in a cool and dry place. The temperature should be maintained at 15-25 ° C, and the relative humidity should be controlled at 40% -60%. If the temperature is too high, it may cause the compound to decompose and evaporate. If the humidity is too high, it may cause it to absorb moisture, agglomerate, and even undergo chemical reactions, which will damage the quality.
Second, it is necessary to pay attention to the influence of light. The compound should be stored away from light because it may undergo photochemical reactions under light conditions, resulting in structural changes and reduced purity and stability. Therefore, the storage container should be made of dark glass or with a light-shielding coating to effectively block light.
Third, the choice of storage container is also the key. It is advisable to use a well-sealed container to prevent contact with air. Oxygen, moisture, carbon dioxide and other components in the air may react with the compound such as oxidation and hydrolysis. Such as glass bottles, plastic bottles, etc., it is necessary to ensure that the seal is tight, and the material should not chemically react with the compound.
Fourth, it is necessary to pay attention to the isolation from other substances. 5- (Methylthiophene) thiophene-2 -formaldehyde should not be stored with oxidants, reducing agents, acids, alkalis and other substances. Due to its active chemical properties, contact with the above substances, or cause violent chemical reactions, such as combustion, explosion, etc., endangering storage safety.
Fifth, the storage period cannot be ignored. Even if the storage conditions are suitable, the compound has a certain shelf life. It is necessary to regularly conduct quality inspections of the stored compounds to check whether their appearance, purity and other indicators have changed. If it exceeds the shelf life or shows signs of deterioration, it must not be reused. It should be properly disposed of in accordance with relevant regulations.

5 - (methylthiophene) thiophene-2 -formaldehyde, this substance is in the market, its price is variable, and it varies with many conditions.
In the field of Guanfu Chemical Industry, the price of materials is often tied to the state of supply and demand. If there are many people in the market who want 5 - (methylthiophene) thiophene-2 -formaldehyde, and there are few people who supply it, the price will increase; on the contrary, if the supply exceeds the demand, the price will drop.
It is also related to the difficulty of its production. The preparation of this substance may require exquisite methods, rare materials, or complicated techniques, so the cost will be high, and its price in the market will also be high. If the preparation method is simple and the materials used are common, the price may be close to the people.
The place of origin also matters. If it is transported from a distance, the cost of transportation and preservation will increase the price. Local production, if there is no burden from a long distance, the price may be slightly lower.
Furthermore, changing times, policy regulations, and price changes of raw materials can cause price fluctuations of 5- (methylthio) thiophene-2-formaldehyde. To know the exact market price, when consulting chemical material suppliers or visiting professional chemical trading platforms, the current actual price can be obtained to avoid misjudgment.