5-Methyl-2-[(2-nitrophenyl)amino]thiophene-3-carbonitrile

5-Methyl-2- [ (2-nitrophenyl) amino] thiophene-3-formonitrile has a wide range of uses. In the field of medicine, it is often used as a key intermediate to help the development of new drugs. All antibacterial and anti-cancer drugs may be used to build specific chemical structures to enhance drug power and optimize efficacy.
In the field of materials science, it also has its own influence. Due to its unique chemical structure and electronic properties, it can participate in the synthesis of materials with special photoelectric properties. Such as organic Light Emitting Diode (OLED) materials, which are used in the manufacture of display screens, can make the screen better color rendering and lower energy consumption. Or used in solar cell materials to improve photoelectric conversion efficiency and promote the development of clean energy.
Furthermore, in the field of scientific research, as an important substrate in organic synthetic chemistry, chemists use it to explore new reaction paths and expand chemical synthesis methods. Through chemical modification and transformation, more compounds with novel structures and specific properties are created, which contribute to the development of chemistry. In short, 5-methyl-2- [ (2-nitrophenyl) amino] thiophene-3-formonitrile has important value in many fields and has unlimited potential.

The synthesis method of 5-methyl-2-[ (2-nitrophenyl) amino] thiophene-3-formonitrile is important in the field of chemical synthesis. There are many methods, and several common methods are described in detail below.
First, thiophene derivatives are used as starting materials and obtained through multi-step reactions. First, thiophene is substituted with suitable reagents under specific conditions, and methyl groups are introduced into the thiophene ring. This step requires careful selection of reaction conditions and reagents to ensure good reaction selectivity and high yield. For example, a halogenated methane can be selected to carry out nucleophilic substitution reaction with thiophene under the catalysis of a base.
Then, the methyl-containing thiophene derivative is reacted with 2-nitroaniline to form the desired amino connection. This reaction may require the help of a specific catalyst to create a suitable reaction environment to promote the effective combination of the two. For example, a specific transition metal catalyst is used to adjust the reaction temperature and time to ensure the smooth progress of the reaction.
Second, other sulfur-containing and nitrogen-containing compounds can also be used as starting materials to construct thiophene rings through cyclization reactions, and the required substituents are introduced simultaneously. This process requires fine design of the reaction path and clever use of various reaction mechanisms. For example, using some sulfur-containing and nitrogen-containing raw materials, under acidic or basic conditions, through intramolecular cyclization, thiophene structures are formed, and methyl, amino and cyano groups are introduced at the same time.
Or first synthesize the thiophene parent containing some substituents, and then gradually introduce the remaining substituents through subsequent reactions. This path requires precise control of the sequence of each step and the reaction conditions. For example, thiophene containing methyl and cyano is synthesized first, and then 2-nitrophenylamino is introduced.
There are many methods for the synthesis of 5-methyl-2 - [ (2-nitrophenyl) amino] thiophene-3-formonitrile, and each method has its advantages and disadvantages. Experimenters need to weigh the advantages and disadvantages according to their own experimental conditions, raw material availability and purity requirements of the target product, and carefully choose the appropriate synthetic route.

5-Methyl-2- [ (2-nitrophenyl) amino] thiophene-3-formonitrile is a kind of organic compound. Its physical properties, let me tell them one by one.
Looking at its appearance, under room temperature and pressure, it is mostly in a solid state. As for the color, or white to light yellow powder, this is due to the characteristics of functional groups and chemical bonds contained in the molecular structure. The interaction of nitro, amino and thiophene rings in the cover molecule affects light absorption and reflection, so it presents such a color.
The melting point, after many experiments, is about [X] ℃. The value of the melting point is closely related to the intermolecular forces. The interactions between molecules, such as van der Waals forces and hydrogen bonds, determine the energy required to transform from solid to liquid. In this compound molecule, the strong electron-absorbing properties of nitro groups enhance the intermolecular forces, which in turn affect the melting point.
In terms of solubility, in organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), it exhibits good solubility. Due to the fact that its molecules have a certain polarity, they can form suitable interactions with organic solvent molecules, such as dipole-dipole interactions, which help them disperse in solvents. However, the solubility in water is poor, because the polarity of the water molecule does not match the polarity of the compound well, and the hydrophobic thiophene ring and phenyl part in the compound prevent it from dissolving with the water phase.
In addition, its density is also one of the important physical properties. After precise measurement, it is about [X] g/cm ³. The size of the density reflects the compactness of the molecule. The spatial arrangement of the molecular structure of the compound determines the amount of mass per unit volume. The physical properties of 5-methyl-2-[ (2-nitrophenyl) amino] thiophene-3-formonitrile are determined by its unique molecular structure, which is essential for applications in organic synthesis, materials science, and other fields.

5-Methyl-2- [ (2-nitrophenyl) amino] thiophene-3-formonitrile, an organic compound. Its chemical properties are unique and related to various fields such as organic synthesis and materials science.
In this compound, the thiophene ring is the key structure, which endows it with specific electronic properties and stability. The 5-position methyl group can affect the spatial configuration and electron cloud distribution of the molecule, which in turn affects its physical and chemical properties. 2-position linked (2-nitrophenyl) amino group, nitro has strong electron absorption, which can significantly change the electron density of the molecule, resulting in changes in the reactivity of the thiophene ring.
From the perspective of reactivity, amino and cyanyl groups can participate in various chemical reactions because of their structure. The nitrogen atom of the amino group contains lone pairs of electrons and is nucleophilic. It can undergo nucleophilic substitution reactions with electrophilic reagents, such as reacting with acyl halides and halogenated hydrocarbons, etc., to generate corresponding derivatives, thereby expanding the structure and function of the molecule. Cyanyl groups can participate in hydrolysis reactions and be converted into carboxyl groups; or form amino groups through reduction reactions, enriching the derivation pathways of compounds.
Furthermore, due to the existence of conjugated systems, the compound may have unique properties in terms of light and electricity. The conjugated structure is conducive to electron delocalization, or makes the compound have certain optical absorption and emission characteristics, which has potential application value in the field of optoelectronic materials, such as the preparation of organic Light Emitting Diodes, solar cell materials, etc.
In addition, its solubility is controlled by molecular polarity. Although it contains polar groups, the hydrophobicity of the overall molecular structure cannot be underestimated, or it has better solubility in organic solvents. This property is very important for its reaction in solution and material processing. In the organic synthesis process, the reaction conditions and solvents need to be reasonably selected according to their chemical properties to achieve efficient synthesis and desired reaction results.

I have not heard the exact price of "5 - Methyl - 2 - [ (2 - nitrophenyl) amino] thiophene - 3 - carbonitrile" in the market. The price of this compound may vary depending on the application, purity, supply and demand.
If you ask for its price, you should ask the chemical suppliers. In the world of Tiangong Kaiwu, there is no trade in such fine chemicals. However, today is different from the past. The chemical industry is prosperous. If you want to know its price, you can visit professional chemical trading platforms, such as Gade Chemical Network, Mobell Chemical, etc., or contact well-known reagent suppliers such as Sigma - Aldrich and TCI.
The supplier sets the price according to the quantity and purity of the product. Generally speaking, the price per gram for high purity and small quantity may be tens to hundreds of yuan; if the quantity is large and the purity is slightly lower, the price per gram may be reduced to a few to tens of yuan. But this is only speculation, and the actual price must be subject to the quotation of each supplier.