What is the chemical structure of 5-chloro-N- [[ (5S) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl] oxazolidin-5-yl] methyl] thiophene-2-carboxamide?

5 - chloro - N - [[ (5S) -2 - oxo - 3 - [4 - (3 - oxomorpholin - 4 - yl) phenyl] oxazolidin - 5 - yl] methyl] thiophene - 2 - carboxamide is the English name of an organic compound. If you want to know its chemical structure, please listen to me in detail.

Looking at the name, it can be seen that this compound contains many structural fragments. " 5-Chloro "Epithiophene ring has a chlorine atom substitution at position 5;" thiophene-2-carboxamide "shows the main body of thiophene-2-formamide structure.

" N - [ (5S) -2 -oxo-3- [4- (3 -oxomorpholin-4-yl) phenyl] oxazolidin-5-yl] methyl] "This part indicates that the amide nitrogen atom is connected to a specific structure. Among them, [ (5S) -2 - oxo - 3 - [4 - (3 - oxomorpholin - 4 - yl) phenyl] oxazolidin - 5 - yl] methyl is an oxazolidinone structure containing chiral centers. ( 5S) The chiral carbon configuration of the oxazolidinone ring at position 5 is S type; the 2-oxo epizolidinone ring at position 2 has a carbonyl group; 3- [4- (3-oxomorpholin-4-yl) phenyl] shows that the oxazolidinone ring at position 3 is connected with a phenyl group, and the phenyl group at position 4 is connected with a 3-oxomorpholine-4-group; and the oxazolidinone ring at position 5 is connected to amide nitrogen through methylene.

In summary, the chemical structure of this compound is composed of the chlorothiophene formamide part and the oxazolidinone containing a specific substituted phenyl group connected by methylene. The structure is complex and delicate, and the parts are connected to each other to form a unique chemical entity.

What are the main uses of 5-chloro-N- [[ (5S) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl] oxazolidin-5-yl] methyl] thiophene-2-carboxamide?

5-chloro-N- [[ (5S) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl] oxazolidin-5-yl] methyl] thiophene-2-carboxamide, which is the name of an organic compound, which is mostly used in the field of medicinal chemistry, especially in the field of drug development.

Looking at the structure of this compound, there are specific functional groups and structural units. In drug design, such structures can interact with specific targets in vivo. In the process of anti-tumor drug exploration, it may interfere with the growth, proliferation, differentiation and apoptosis of tumor cells by combining with key proteins or enzymes in tumor cells, so as to inhibit tumors.

In the field of antimicrobial drug research and development, this compound may also exhibit unique activities. Its structural characteristics may enable it to cross the bacterial cell wall and cell membrane, interact with key metabolic enzymes or genetic materials in bacteria, destroy the normal physiological function of bacteria, and achieve the purpose of antibacterial.

Or in the field of neurological drug research, this compound can penetrate the blood-brain barrier and interact with nerve cell surface receptors or ion channels to regulate the release and transmission of neurotransmitters, which may have potential value in the treatment of nervous system diseases.

Furthermore, in the process of pharmaceutical chemistry optimization, this compound is used as the lead structure, and by modifying its side chains, functional groups, etc., its physicochemical properties and biological activities can be adjusted, improving the efficacy of the drug, reducing toxic and side effects, and paving the way for the birth of new and efficient drugs.

What are the physical properties of 5-chloro-N- [[ (5S) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl] oxazolidin-5-yl] methyl] thiophene-2-carboxamide?

5 - chloro - N - [[ (5S) -2 - oxo - 3 - [4 - (3 - oxomorpholin - 4 - yl) phenyl] oxazolidin - 5 - yl] methyl] thiophene - 2 - carboxamide is an organic compound. Its physical properties are as follows:

In terms of appearance, this compound is mostly crystalline and is caused by the orderly arrangement of molecular interactions. As for the color, it is often white or off-white, which is common to most organic crystalline compounds. The cover absorbs visible light weakly due to its molecular structure.

Melting point is quite important. The specific melting point of this compound is determined by intermolecular forces, including hydrogen bonds, van der Waals forces, etc. The exact melting point needs to be determined experimentally, but its range can vary depending on purity and crystal morphology.

Solubility is also a key physical property. In organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), etc., it exhibits a certain solubility. This is because these solvents can form interactions with compound molecules, such as dipole-dipole interactions, which help them disperse in the solvent. However, in water, the solubility is poor, and the hydrophobic part of the molecule accounts for a large proportion, making it difficult to form an effective force between water molecules and compounds.

In addition, the density of the compound also has its own specific value, which is determined by the molecular mass and the degree of crystal packing. Although the exact density needs to be measured by special instruments, it can theoretically be estimated according to its molecular structure and crystal form.

Its stability cannot be ignored. Under normal conditions, it has a certain stability. In case of extreme conditions such as strong acid, strong base or high temperature, the molecular structure may change, triggering chemical reactions and causing changes in its physical properties.

What are the synthesis methods of 5-chloro-N- [[ (5S) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl] oxazolidin-5-yl] methyl] thiophene-2-carboxamide?

5-chloro-N- [[ (5S) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl] oxazolidin-5-yl] methyl] thiophene-2-carboxamide an organic compound. The method of synthesizing this compound has been used by chemists in the past.

First, thiophene-2-carboxylic acid with a specific substituent is used as the starting material. First, thiophene-2-carboxylic acid is interacted with an appropriate halogenating agent to introduce a chlorine atom at its 5th position to obtain 5-chlorothiophene-2-carboxylic acid. Then, this acid is esterified with alcohols containing specific structures in the presence of condensing agents such as dicyclohexyl carbodiimide (DCC) and catalyst 4-dimethylaminopyridine (DMAP) to form corresponding esters.

Second, prepare [ (5S) -2 - oxo - 3 - [4 - (3 - oxomorpholin - 4 - yl) phenyl] oxazolidin - 5 - yl] methylamine moiety. Starting from a chiral source, the oxazolidinone ring structure was constructed by multi-step reaction. The key intermediate is formed by nucleophilic substitution or condensation reaction between the compound with chiral center and the reagent containing 4 - (3 - oxomorpholin - 4 - yl) phenyl substituent. This intermediate is then reduced or other functional group conversion reactions to obtain [ (5S) -2 - oxo - 3 - [4 - (3 - oxomorpholin - 4 - yl) phenyl] oxazolidin - 5 - yl] methylamine.

Finally, 5-chlorothiophene-2-carboxamide was prepared by ammonolysis of 5-chlorothiophene-2-carboxamide with [ (5S) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl] oxazolidin-5-yl] methylamine under alkali catalysis, and the ester group was converted into an amide group to obtain 5-chloro-N- [[ (5S) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl] oxazolidin-5-yl] methyl] thiophene-2-carboxamide ... < Br >
Synthesis requires attention to the precise control of reaction conditions, such as temperature, pH, reaction time, etc., to ensure the selectivity and yield of each step of the reaction, and each intermediate needs to be separated and purified to ensure the purity of the final product.

What is the competitive advantage of 5-chloro-N- [[ (5S) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl] oxazolidin-5-yl] methyl] thiophene-2-carboxamide in the market?

Guanfu 5 - chloro - N - [[ (5S) -2 - oxo - 3 - [4 - (3 - oxomorpholin - 4 - yl) phenyl] oxazolidin - 5 - yl] methyl] thiophene - 2 - carboxamide has multiple competitive advantages in the market.

First, from the perspective of pharmacological efficacy, its mechanism of action is unique, and it can precisely act on specific targets, just like a good arrow. With its treatment of related diseases, it can efficiently regulate physiological and pathological processes, such as targeting key pathways of diseased cells and curbing the progression of disease, which is beyond the reach of many similar species. Its curative effect is exact, and clinical verification shows that it can often play a miraculous effect on the improvement of the corresponding disease, and the patient's symptoms are relieved significantly, and the recovery is expected.

Second, in terms of safety, after rigorous experimental investigation, its side effects are mild. It is like walking on a boat in the river, with no waves. Within the therapeutic dose range, it rarely causes serious adverse reactions, and it has little interference with the patient's body, which makes the doctor more confident when taking medicine, and the patient can also take it with peace of mind.

Furthermore, the research and development process is exquisite. During the preparation process, advanced technology is used to ensure the uniform and stable quality of the product. Just like the finely crafted jade, the quality is high. The production efficiency is also high, and the cost can be effectively controlled, which is quite advantageous in the market price competition.

And its market positioning is accurate, targeting specific disease groups, with high demand fit. It is like tailoring, just right. Effective publicity and promotion, let more doctors and patients know its effectiveness, and lay a solid foundation for its competition in the market.