What is the chemical structure of 5-Chloro-N- ((5S) -2-oxo-3- (4- (3-oxomorpholin-4-yl) phenyl) -1,3-oxazolidin-5-yl) methyl) thiophene-2-carboxamide?

In the naming of this organic compound, it is lengthy and complicated, and it is not easy to clarify its chemical structure. However, based on what I know about chemistry, let me explain it in detail.

In the naming of this compound, "5 - Chloro - N - ((5S) -2 - oxo - 3 - (4 - oxomorpholin - 4 - yl) phenyl) -1,3 - oxazolidin - 5 - yl) methyl) thiophene - 2 - carboxamide", where "5 - Chloro" refers to the substitution of a chlorine atom at the 5th position of the thiophene ring. " Thiophene-2-carboxamide "indicates that this is the structural main body of thiophene-2-formamide.

And the" N - ((5S) -2 - oxo - 3- (4- (3 - oxomorpholin - 4 - yl) phenyl) -1,3 - oxazolidin - 5 - yl) methyl) "part is a substituent attached to the nitrogen atom of thiophene formamide. Wherein " (5S) -2 -oxo-1,3 -oxazolidin-5-yl" is a chiral azolidin-2-one structure, and the 5-position is of the S configuration. The 3-position of the azolidin-2-one is connected to a phenyl group, and the 4-position of the phenyl group is connected with a "3-oxomorpholin-4-yl" (3-oxomorpholin-4-yl) structure. At the same time, the 5-position of the azolidin-2-one is connected to the nitrogen atom of thiophenylformamide through methylene (-CH 2O -).

In summary, the chemical structure of this compound is composed of thiophene-2-formamide as the main body, and a complex substituent is connected to its nitrogen atom. The substituent contains chiral azolidine-2-one, phenyl and morpholine derivatives and other structural units. Each part is connected according to specific rules to form this unique chemical structure. Although it is difficult to explain in detail, the general structure is already clear.

What are the physical properties of 5-Chloro-N- ((5S) -2-oxo-3- (4- (3-oxomorpholin-4-yl) phenyl) -1,3-oxazolidin-5-yl) methyl) thiophene-2-carboxamide?

5 - Chloro - N- ((5S) -2 - oxo - 3- (4- (3 - oxomorpholin - 4 - yl) phenyl) -1,3 - oxazolidin - 5 - yl) methyl) thiophene - 2 - carboxamide is an organic compound. Its physical properties are as follows:

From the perspective of normal temperature and pressure, this compound may be a solid, but it must also depend on its chemical structure and intermolecular forces. If the intermolecular forces are strong, such as hydrogen bonds, van der Waals forces, etc., it is easy to form a solid structure.

As for the melting boiling point, due to the complex molecular structure of the compound, it contains many polar groups, such as carbonyl and amide groups, which can form intermolecular hydrogen bonds, greatly enhance the intermolecular force, and cause its melting point to be higher. For accurate determination, experimental investigation is needed to obtain the exact value.

In terms of solubility, in view of the polar groups in its molecules, theoretically in polar solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO), there may be some solubility. Hydrogen bonds or other interactions can be formed between polar solvent molecules and polar groups of the compound to help it dissolve. However, in non-polar solvents such as n-hexane and toluene, the solubility is poor, because the interaction between non-polar solvents and polar compounds is weak.

In addition, the density of this compound is also affected by its molecular structure and packing method. Due to the complex structure, density or relatively large, the exact value still needs to be measured experimentally. Its behavior in solution, such as molecular aggregation states, is also closely related to the molecular structure. The interaction between polar groups or the formation of certain molecular aggregation phenomena in solution.

5-Chloro-N- ((5S) -2-oxo-3- (4- (3-oxomorpholin-4-yl) phenyl) -1,3-oxazolidin-5-yl) methyl) thiophene-2-carboxamide in which areas are used?

5 - Chloro - N - ((5S) -2 - oxo - 3- (4- (3 - oxomorpholin - 4 - yl) phenyl) -1,3 - oxazolidin - 5 - yl) methyl) thiophene - 2 - carboxamide is a complex organic compound with important applications in medicine, chemical industry and other fields.

In the field of medicine, such compounds often have unique biological activities or can be used as potential pharmaceutical active ingredients. Due to their specific chemical structure, they may be able to act precisely on specific biological targets in the body, such as certain enzymes or receptors. After in-depth research and optimization, it is expected to be developed into new drugs for the treatment of a variety of diseases, such as inflammation, tumors, etc. For example, by modulating specific signaling pathways, it can affect the process of cell proliferation, differentiation and apoptosis, so as to achieve the purpose of treating diseases.

In the chemical industry, it may be used as an intermediate in organic synthesis. With its own structural characteristics, it can participate in many organic reactions to synthesize more complex and unique organic compounds. By reacting with other reagents, novel chemical structures are constructed, laying the foundation for the preparation of high-performance materials, special functional chemicals, etc. With its unique chemical structure, this compound has shown broad application prospects in key fields such as pharmaceutical research and development and chemical synthesis, and continues to attract many researchers to explore its potential value and application pathways.

What is the synthesis method of 5-Chloro-N- ((5S) -2-oxo-3- (4- (3-oxomorpholin-4-yl) phenyl) -1,3-oxazolidin-5-yl) methyl) thiophene-2-carboxamide?

The synthesis of 5-chloro-N- [ (5S) -2-oxo-3- (4- (3-oxo-morpholine-4-yl) phenyl) -1,3-oxazolidine-5-yl] methyl] thiophene-2-formamide is a delicate subject in organic synthetic chemistry. The complex structure of this compound requires several delicate reactions.

The initial step is to construct the basic structure of thiophene and oxazolidine with suitable starting materials. Thiophene derivatives with corresponding substituents can be selected, and the 2-position of thiophene can be introduced into the formyl group through acylation reaction. This acylation reaction, or the mild reaction of an acyl halide with a thiophene derivative in an inert solvent under the catalysis of a suitable base, can achieve this purpose.

Then, the oxazolidine part is constructed. Compounds containing specific substituted phenyl groups and chiral amino acid derivatives are used as raw materials for condensation reaction to form oxazolidine rings. This condensation process requires fine regulation of the reaction conditions to ensure the precise generation of the (5S) configuration.

Subsequently, the formed thiophene formyl part is connected to the oxazolidine intermediate. This connection step, or the nucleophilic substitution reaction, reacts the activity check point of the thiophenoformyl group with the appropriate group on the oxazolidine ring to form a key amide bond. This reaction requires careful selection of reagents and solvents to optimize the reaction yield and selectivity.

During the entire synthesis process, the conditions of each step of the reaction need to be carefully controlled, such as temperature, reaction time, and reactant ratio. And each step needs to be completed by appropriate analytical methods, such as thin-layer chromatography, nuclear magnetic resonance, etc., to confirm the structure and purity of the product before proceeding to the next step of the reaction. In this way, step by step and careful operation, the target product 5-chloro-N-[ (5S) -2-oxo-3- (4- (3-oxo-morpholine-4-yl) phenyl) -1,3-oxazolidine-5-yl] methyl] thiophene-2-formamide is expected to be obtained.

What is the market outlook for 5-Chloro-N- ((5S) -2-oxo-3- (4- (3-oxomorpholin-4-yl) phenyl) -1,3-oxazolidin-5-yl) methyl) thiophene-2-carboxamide?

Guanfu 5 - Chloro - N- ((5S) -2 - oxo - 3- (4- (3 - oxomorpholin - 4 - yl) phenyl) -1,3 - oxazolidin - 5 - yl) methyl) thiophene - 2 - carboxamide This product, in today's market prospects, is really the field that many businesses are looking forward to and everyone is looking forward to.

From the perspective of pharmaceutical research and development, this compound has a unique structure and contains exquisite structures. It may have unique functions in the process of creating new drugs. Today's pharmaceutical industry is hungry for high-efficiency, low-toxicity and specific drugs. The structural characteristics of this compound may provide the possibility to target specific disease targets. If it can precisely act on certain disease-related biomacromolecules, such as specific enzymes, receptors, etc., it is expected to develop a good drug for the treatment of difficult diseases. Its market prospect is immeasurable.

In the process of research and development, although there are many thorns, opportunities also accompany it. Researchers need to go through many experiments to analyze its pharmacological mechanism at the molecular level and explore its interaction with various components in the body. If they can successfully overcome many barriers and reveal its therapeutic potential, it will surely lead to changes in the pharmaceutical market.

Furthermore, from the perspective of market competition, if we can take the lead in bringing drugs based on this compound to the market, we will definitely be able to take the lead in the fierce market competition. Many pharmaceutical companies have also gained insight into the business opportunities and have invested in related research. Therefore, in order to emerge in this field, we need to race against time, and with exquisite technology and keen insight, we can come out on top.

In summary, 5 - Chloro - N - ((5S) -2 - oxo - 3 - (4 - (3 - oxomorpholin - 4 - yl) phenyl) -1,3 - oxazolidin - 5 - yl) methyl) thiophene - 2 - carboxamide market prospects, although there are challenges, but full of opportunities, if well grasped, will be able to open up a bright territory in the vast world of the pharmaceutical market.