5 Bromo N Tert Butylthiophene 2 Sulfonamide
quinoline thiophene imidazole thiazole

5-bromo-N-tert-butylthiophene-2-sulfonamide

Taiy Chemical

    Specifications

    HS Code

    642688

    Chemical Formula C8H12BrNO2S2
    Molar Mass 298.22 g/mol
    Appearance Solid (likely, based on common sulfonamide properties)
    Physical State At Room Temperature Solid
    Solubility In Water Low (sulfonamides are generally sparingly soluble in water due to non - polar groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (due to presence of organic moieties)
    Odor Odorless or faint odor (common for sulfonamides)

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    General Information
    Where to Buy 5-bromo-N-tert-butylthiophene-2-sulfonamide in China?
    As a trusted 5-bromo-N-tert-butylthiophene-2-sulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 5-bromo-N-tert-butylthiophene-2-sulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 5-bromo-N-tert-butylthiophene-2-sulfonamide?
    The chemical properties of 5-% ether-N-benzylamino-2-chloropyridine are quite unique. In this compound, the presence of ether bonds gives it certain stability and solubility. The groups at both ends of the ether bond interact with each other, making the overall structure and properties of the molecule different.
    -N-benzylamino moiety, the introduction of benzyl adds hydrophobicity to the molecule, and the electron cloud distribution of benzyl can produce electronic effects on amino groups. Amino groups are alkaline and can react with acids under appropriate conditions to form salt compounds. At the same time, the steric resistance of benzyl groups also affects the reactivity and selectivity of the molecule.
    2-chloropyridine part, the chlorine atom is highly electronegative, and it is connected to the pyridine ring, which will change the electron cloud density distribution of the pyridine ring. The pyridine ring is aromatic, and the substitution of chlorine atoms makes the electron cloud distribution on the ring uneven, which in turn affects the activity of the electrophilic substitution and nucleophilic substitution of the pyridine ring. Generally speaking, the electron cloud density of the neighboring and para-site of the chlorine atom is relatively reduced, and the electron cloud density of the meta-site is relatively increased, so the electrophilic substitution reaction is more likely to occur in the meta-site. In the nucleophilic substitution reaction, the chlorine atom can be used as the leaving group and be replaced under the action of
    In addition, there are interactions between different groups in this compound, such as the synergy or antagonism of electronic effects and spatial effects, which jointly determine its chemical properties. In chemical reactions, the reactive activities of each part are interrelated and mutually restricted, making it show unique application value in organic synthesis, medicinal chemistry and other fields. It can be used as a key intermediate to participate in the construction of a variety of complex compounds.
    What are the preparation methods of 5-bromo-N-tert-butylthiophene-2-sulfonamide?
    5-Hydroxy-N-methylpyrrole-2-formaldehyde, this is an organic compound. The preparation methods are various, and the details are as follows:
    1. ** Pyrrole is used as the starting material **: Pyrrole is first N-methylated, often with methylating reagents such as iodomethane, under the action of appropriate bases such as potassium carbonate, to generate N-methylpyrrole. Subsequently, N-methylpyrrole was reacted with N, N-dimethylformamide (DMF) and phosphorus oxychloride (POCl) as reagents at low temperature through Vilsmeier-Haack reaction, and formyl groups could be introduced at the 2-position of the pyrrole ring to obtain 5-hydroxyl-N-methylpyrrole-2-formaldehyde. This reaction condition needs to be precisely controlled, and factors such as reaction temperature and reagent dosage ratio have a significant impact on the yield and purity of the product.
    2. ** Construction of pyrrole ring by cyclization reaction **: Using suitable compounds containing nitrogen, carbonyl and hydroxyl groups as raw materials, pyrrole ring is constructed by intramolecular cyclization reaction. For example, using 4-amino-3-pentene-2-one and hydroxyacetaldehyde as raw materials, under acid catalysis, intramolecular cyclization occurs, and methyl, formyl and hydroxyl groups are introduced at the same time to synthesize the target product. In this process, conditions such as the type and dosage of acid, reaction time and temperature have a great influence on the cyclization reaction process.
    3. ** Using metal-catalyzed reaction **: Metal-catalyzed coupling reaction can also be one of the preparation routes. For example, halogenated N-methyl pyrrole derivatives and formaldehyde sources can achieve 5-position hydroxylation and 2-position formylation under the action of palladium and other metal catalysts and ligands. In this method, the activity of metal catalysts, the structure and dosage of ligands, as well as the choice of reaction solvent and base, all play an important role in the reaction effect.
    When preparing 5-hydroxyl-N-methyl pyrrole-2-formaldehyde, it is necessary to carefully select the appropriate preparation method according to the actual situation, comprehensively considering the availability of raw materials, the feasibility of reaction conditions, cost-effectiveness and other factors.
    What are the applications of 5-bromo-N-tert-butylthiophene-2-sulfonamide?
    5-HT-N-pentyltryptamine-2-receptor (5-HT-N-pentyltryptamine-2-receptor), also known as 5-HT2 receptor, has important applications in many fields.
    In the field of medicine, it is a key target for the development of psychotropic drugs. Many antipsychotic drugs, such as clozapine and olanzapine, act on the 5-HT2 receptor to regulate neurotransmitter transmission and achieve the effect of treating schizophrenia, depression and other psychiatric diseases. Some drugs for the treatment of migraine also target 5-HT2 receptors, which relieve migraine symptoms by modulating cerebrovascular tone and neurogenic inflammation.
    In the field of the nervous system, 5-HT2 receptors are involved in neurodevelopment, synaptic plasticity and neurotransmission regulation. Studies have shown that this receptor is widely distributed in the cerebral cortex, hippocampus, amygdala and other regions, and is essential for neurological functions such as learning, memory, and emotion regulation. Its dysfunction is related to the occurrence and development of a variety of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.
    In the cardiovascular field, 5-HT2 receptors have a regulatory effect on cardiovascular activity. Activation of this receptor can cause vasoconstriction and increase blood pressure; and blocking this receptor may prevent and treat cardiovascular diseases, such as hypertension and coronary heart disease.
    Furthermore, in the gastrointestinal field, 5-HT2 receptors are distributed in the smooth muscle of the gastrointestinal tract and the enteric nervous system, and are involved in gastrointestinal movement, secretion and sensory regulation. Some drugs for gastrointestinal disorders may work by acting on 5-HT2 receptors. 5-Hydroxy- N-pentyltryptamine-2-receptor plays an important role in many fields such as medicine, neurology, cardiovascular and gastrointestinal tract. In-depth research on it may open up new ideas for the treatment and prevention of related diseases.
    What are the market prospects for 5-Bromo-N-tert-butylthiophene-2-sulfonamide?
    In recent years, pentachloro-N-benzylformamide-2-bromopyridine has emerged in various fields, and its market prospect is quite promising. At present, this compound has opportunities in the fields of pharmaceutical creation, agrochemical development and material science, and it is gaining popularity.
    In the field of medicine, because of its unique chemical conformation and biological activity, it can pave the way for the development of new drugs. At present, the research of medicine is becoming more and more refined, and the demand for molecules with specific pharmacological effects is increasing. Pentachloro-N-benzylformamide-2-bromopyridine can be used as a key intermediate to help synthesize targeted and highly effective drugs, such as anti-cancer and anti-infection agents. This is a great opportunity for the pharmaceutical industry. Its market demand is expected to rise with the advance of pharmaceutical research.
    As for agrochemical, modern agriculture is eager for high-efficiency, low-toxicity and environmentally friendly pesticides. The characteristics of this compound may lead to new pesticides, fungicides and other agrochemical products, which not only ensure the prosperity of crops, but also take into account the ecological balance. With the growing global concern for food safety and environmental protection, such new agrochemical products will definitely gain market favor, and the market expansion space is vast.
    In materials science, pentachloro-N-benzylformamide-2-bromopyridine can also contribute to the creation of novel functional materials. Such as the development of polymer materials with special properties, or emerging in the field of electronic and optical materials. Technological evolution has promoted diverse and high-end material requirements. The application of this compound in this field is expected to open up a new market territory.
    In summary, pentachloro-N-benzylformamide-2-bromopyridine has promising market prospects due to its potential applications in many fields. Although it may not be prosperous at present, over time, with the deepening of scientific research and industrial expansion, it will be able to gain a place in various relevant markets and become an important driving force for the development of the industry.
    What are the storage conditions for 5-Bromo-N-tert-butylthiophene-2-sulfonamide?
    The storage conditions of 5-% ether-N-benzylacetamide-2-cyanone are crucial to the maintenance of its quality and the survival of its efficacy. This medicine should be placed in a cool, dry and well-ventilated place.
    A cool place can avoid the harm of high temperature. If it is in a high temperature environment, the ingredients of the medicine may decompose and deteriorate due to heat, resulting in the impairment of its efficacy. For example, in summer, when the sun is high, if the medicine is exposed to sunlight or placed in a high temperature room, the molecular structure in the medicine may be affected and the efficacy will gradually lose. Therefore, in terms of temperature, it should be controlled between 15 and 25 degrees Celsius, which can ensure the stability of the medicine. < Br >
    Dry places can be waterproof to moisture. If the medicine is damp, it is prone to mildew and deliquescence. If moisture enters, or some ingredients in the medicine dissolve and react, destroying its original structure. For example, during the rainy season in the south, the air humidity increases greatly. If the medicine is not properly stored, it is very susceptible to moisture. Therefore, the relative humidity of the air should be maintained between 45% and 75% to prevent moisture damage.
    Well ventilated, it can circulate the air and disperse the moisture and odor that may accumulate. If the environment is blocked, the medicine may be eroded by turbid gas, and it is not conducive to moisture emission.
    Furthermore, this medicine should be kept away from fire sources and power sources. Due to the flammability or conductivity of some of the ingredients in the drug, it may be exposed to fire or electricity, or cause danger, causing harm to people and injuries.
    It is also necessary to separate it from other drugs to avoid odor or chemical reactions. Different drug ingredients are different, mixed in one place, or interact with each other to change the medicinal properties.
    Store this 5-% ether-N-benzylacetamide-2-cyanone, and be sure to observe the above conditions to ensure its quality and efficacy for emergencies.