5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate

5-Amino-4-cyano-3- (2-ethoxy-2-oxyethyl) thiophene-2-carboxylic acid esters are widely used in medicine, chemical industry and other fields.
In the field of medicine, this compound is often the key intermediate for creating new drugs. Due to its unique structure, it contains active groups such as amino, cyano and thiophene rings, which can be modified and transformed by organic synthesis and combined with specific targets. For example, in the research and development of anti-tumor drugs, through structural modification, new molecules with inhibitory effect on cancer cell proliferation may be obtained, which can exert anti-cancer effect by interfering with cancer cell metabolism and blocking signal transduction pathways.
In the chemical industry, its uses are also rich. Or as a raw material for the preparation of special functional materials. Because the thiophene ring structure gives it specific photoelectric properties, it can be used for the preparation of organic optoelectronic materials. By polymerization and other means, it is expected to be introduced into polymer materials with unique optical and electrical properties for use in organic Light Emitting Diode (OLED), solar cells and other devices to improve their performance and efficiency.
Furthermore, in the research and development of pesticides, the compound may have potential value. Because of its active groups, it may have inhibitory or killing effects on some pests and pathogens. After rational structure optimization and activity screening, new pesticides with high efficiency, low toxicity and environmental friendliness may be developed, which will help the sustainable development of agriculture.
In short, 5-amino-4-cyano-3- (2-ethoxy-2-oxyethyl) thiophene-2-carboxylic acid esters have important application potential in many fields due to their unique chemical structure, and are valued by scientific research and industrial production.

The synthesis method of 5-amino-4-cyano-3- (2-ethoxy-2-oxyethyl) thiophene-2-carboxylic acid ester can follow the following path.
First take the appropriate starting material and use the thiophene derivative as the base. This derivative needs to be modified in advance by a specific substitution reaction to lay the foundation for the subsequent reaction. For example, the introduction of a substituent at a specific position of the thiophene ring can be achieved by nucleophilic substitution or electrophilic substitution. Here, to introduce the structures of amino, cyano and ethoxy-oxyethyl, the reaction steps and conditions need to be precisely planned.
For the introduction of amino groups, an aminolysis reaction may be used. A thiophene derivative containing suitable leaving groups is used as a substrate, in a suitable solvent, co-placed with an ammonia source, and heated to a suitable temperature to replace ammonia with leaving groups. This process requires attention to the reaction time and the amount of ammonia to ensure the efficiency and accuracy of amino substitution.
The introduction of cyanyl groups can utilize halogenated thiophene derivatives to undergo nucleophilic substitution with cyanides. Cyanide sources such as potassium cyanide and sodium cyanide are selected to react in polar aprotic solvents in the presence of phase transfer catalysts. The reaction environment needs to be strictly controlled to avoid side reactions such as cyanide hydrolysis.
As for the 2-ethoxy-2-oxyethyl moiety, the thiophene ring can be connected by esterification or condensation reaction. First, carboxylic acids containing ethoxy-oxyethyl groups or their active derivatives, such as acyl chloride, are prepared, and then reacted with nucleophilic check points such as hydroxyl or amino groups on thiophene derivatives to form the desired ester group or amide group connection.
After each step of the reaction, purification methods such as column chromatography and recrystallization are required to obtain high-purity intermediate products and final target products 5-amino-4-cyano-3- (2-ethoxy-2-oxyethyl) thiophene-2-carboxylic acid esters, and the conditions of each step of the reaction, such as temperature, solvent, catalyst dosage, etc., are all related to the success or failure of the synthesis and the yield.

5-Amino-4-cyano-3- (2-ethoxy-2-oxyethyl) thiophene-2-carboxylic acid ester is also an organic compound. Its physical and chemical properties are quite important, related to the characteristics and uses of this compound.
In terms of its physical properties, this substance may be in a solid state under normal temperature and pressure. The characteristics of its melting point and boiling point are crucial for the separation, purification and application of compounds. The melting point is the temperature at which the substance changes from solid to liquid state. If the melting point is higher, it indicates that the intermolecular forces are strong and the structure is relatively stable. The same is true for the boiling point. A high boiling point means that a higher energy is required to turn it into a gaseous state.
As for the chemical properties, it contains various functional groups such as amino groups, cyano groups, and ester groups. Amino groups are alkaline and can react with acids to form salts. Cyano groups are more active and can participate in various addition and substitution reactions. Ester groups can undergo hydrolysis reactions catalyzed by acids or bases to generate corresponding acids and alcohols. And the existence of thiophene rings endows this compound with a unique electron cloud distribution and conjugation system, which affects its reactivity and stability.
This compound may have potential uses in organic synthesis, medicinal chemistry and other fields due to the characteristics of the functional groups it contains. In organic synthesis, it can be used as a key intermediate to construct more complex organic molecules through the transformation of various functional groups. In the field of medicinal chemistry, its special structure may interact with specific targets in organisms to exhibit certain biological activities, providing the possibility for the development of new drugs.

I have not heard the market price of "5 + - + amino + - + 4 + - + cyano + - + 3 + - + ( 2 + - + ethoxy + - + 2 + - + oxo ethyl) thiophene + - + 2 + - + carboxylate". The name of this compound varies widely, and the market trade is rare, so it is difficult to determine its price. Although "Tiangong Kaiwu" records all the techniques of creation, it is a modern chemical thing, which is not covered in the book. If you want to know the price, you can consult chemical material suppliers and reagent suppliers, who are often in the market and can know the price rise and fall, or can give you a more accurate number; or you can consult the platform and forum of chemical trading, and discuss with peers.

5-Amino-4-cyano-3- (2-ethoxy-2-oxyethyl) thiophene-2-carboxylate, this substance is life-threatening and should be used with caution.
Looking at its properties, there is no detailed and reliable toxicity and safety conclusion. However, many similar compounds containing cyanide groups and complex organic structures are often toxic. Cyanide can release cyanide ions in the body, highly toxic substances, can block the respiratory chain of cells, causing poisoning, mild symptoms such as headache, dizziness, nausea, severe convulsions, coma, and even life-threatening.
As for the safety of this substance, there are still many unknowns. The organic structure may affect its metabolism and accumulation in living organisms. Some organic compounds are difficult to metabolize in the body, or accumulate in organs and tissues, causing chronic toxicity and damage to the liver, kidney, nervous system and other systems.
In view of this, 5-amino-4-cyano-3- (2-ethoxy-2-oxyethyl) thiophene-2-carboxylate should not be taken lightly. If exposed in experiments, production or other scenes, be sure to strictly follow safety procedures and take good protection, such as protective clothing, protective gloves and masks, to ensure good ventilation. In case of inadvertent contact, it should be flushed with plenty of water as soon as possible, and in severe cases, it is urgent to seek medical attention.
In short, this compound should be treated with awe to ensure life safety and health.