What are the chemical properties of 5-Amino-4-cyano-2- (ethoxycarbonyl) -3-thiopheneacetic acid ethyl ester

5-Amino-4-cyano-2- (ethoxycarbonyl) -3-thiophene ethyl acetate, this is an organic compound. Its chemical properties are unique, let me tell you one by one.

Looking at its structure, it contains functional groups such as amino, cyano, ethoxycarbonyl and thiophene ring. The amino group is alkaline and can form salts with acids. It is often used as a nucleophilic reagent in organic synthesis and participates in many reactions, such as reacting with acyl halides and acid anhydrides to form amides. Cyanyl is highly reactive and can be hydrolyzed into carboxyl groups or reduced to amino groups, and can also participate in cyclization reactions to construct heterocyclic compounds. < Br >
Ethoxycarbonyl is an electron-withdrawing group, which affects the distribution of molecular electron clouds, changes the density of its adjacent and para-site electron clouds, and affects the substitution reaction activity. The thiophene ring is aromatic. Although its stability is inferior to that of the benzene ring, it can undergo electrophilic substitution reaction, and the activities at the 2,5 positions are higher than those at the 3,4 positions.

The overall properties of this compound are affected by the interaction of various functional groups. In terms of solubility, due to the presence of polar functional groups, it has a certain solubility in polar organic solvents such as ethanol and acetone, but it has poor solubility in non-polar solvents such as n-hexane.

In terms of stability, it is relatively stable under general conditions. However, in case of strong acid, strong base or high temperature, the functional group will react and cause structural changes. In chemical reactions, various functional groups cooperate to provide diverse possibilities for organic synthesis, which can be used to prepare complex organic compounds with specific functions and structures, and may have important application value in fields such as medicinal chemistry and materials science.

What are the synthesis methods of 5-Amino-4-cyano-2- (ethoxycarbonyl) -3-thiopheneacetic acid ethyl ester

The synthesis method of 5-amino-4-cyano-2- (ethoxycarbonyl) -3-thiophene ethyl acetate is not directly described in the classic "Tiangong Kaiwu", but one or two can be explored according to the ancient method.

First, you can start from the selection of raw materials. This compound contains functional groups such as cyanyl and ethoxycarbonyl, and it is necessary to find starting materials containing corresponding groups. The introduction of cyanyl can be obtained by nucleophilic substitution reaction between halogenates and cyanide sources such as sodium cyanide. Although the ancient chemistry is not as accurate as modern, it is still possible to replace it with analogs and try it in a simple way.

Second, the construction of ethoxycarbonyl can be obtained by esterification of ethanol and carboxyl-containing compounds. In ancient times, although there were no current catalytic conditions, natural catalysts, such as certain plant extracts or specific ores, may be used to promote their reaction at appropriate temperatures and durations.

Third, the construction of thiophene rings is the key. Or it can be formed by cyclization of sulfur-containing compounds and compounds with conjugated structures. Although ancient alchemy and alchemy were mostly seeking longevity and dipping stone into gold, the experience of chemical changes may be used for reference. After repeated exploration of reaction conditions, such as temperature and reactant ratio, etc., to form thiophene rings.

Fourth, after building the molecular skeleton, the introduction of amino groups can be reduced by methods such as nitro. In ancient times, although there were no modern reducing reagents, it was possible to try to combine metals and acids, such as iron and acetic acid, to slowly reduce nitro groups to amino groups.

All these are based on ancient ideas, using simple raw materials and means to explore ways to synthesize this compound. Although there is no modern precision and efficiency, the spirit of chemical exploration contained in it is the same in ancient times and modern times.

What is the main use of 5-Amino-4-cyano-2- (ethoxycarbonyl) -3-thiopheneacetic acid ethyl ester

5-Amino-4-cyano-2- (ethoxycarbonyl) -3-thiophene ethyl acetate, which has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate, helping to synthesize many bioactive compounds. Due to its structure of cyano, ester and amino functional groups, it can be derived from a variety of chemical reactions, which is of great significance for the development of new drugs, such as antibacterial and anti-tumor drugs.

In the field of materials science, it may also emerge. Because of its thiophene structure, it may endow materials with unique photoelectric properties. Taking conductive polymer materials as an example, by integrating them into the polymer skeleton through a specific reaction, the conductivity and stability of the material may be improved, and then it will gain application opportunities in electronic devices, such as organic Light Emitting Diodes, solar cells and other fields.

Furthermore, in the field of organic synthetic chemistry, it is an important building block for the construction of complex organic molecules. With the characteristics of each functional group and carefully designed reaction paths, multi-step reactions can be realized to synthesize organic compounds with exquisite structures and specific functions, promoting the development of organic synthetic chemistry and laying the foundation for the creation of novel organic materials and drugs.

5-Amino-4-cyano-2- (ethoxycarbonyl) -3-thiopheneacetic acid ethyl ester What are the precautions in storage and transportation?

5-Amino-4-cyano-2- (ethoxycarbonyl) -3-thiophene ethyl acetate, this is a fine chemical substance. When storing and transporting, many matters need to be paid attention to.

First of all, this compound should be stored in a cool and dry place. Due to its nature or susceptibility to temperature and humidity, high temperature and humid places may cause it to deteriorate. For example, if stored in a warehouse without temperature control equipment in summer, the temperature will be too high, or the molecular structure will change, causing its chemical activity to change. Furthermore, ensure that the storage place is well ventilated to prevent the accumulation of volatile gases and cause potential safety hazards. At the same time, it should be stored separately from oxidizing agents, acids, alkalis, etc. This compound is chemically active, comes into contact with the above substances, or causes violent chemical reactions, such as meeting with strong acids and alkalis, or causing reactions such as hydrolysis, destroying its structure.

As for transportation, there are also many details. Make sure that the packaging is in good condition before transportation. The packaging material should have good sealing and corrosion resistance to avoid leakage during transportation. For example, use special plastic drums or glass bottles to pack, and fill and reinforce with inert materials. During transportation, to prevent collisions and vibrations. Because it is a fine chemical, violent vibration or damage to the packaging, and vibration friction or static electricity, causing danger. The means of transportation also need to be considered. Vehicles that are clean, dry and have temperature control equipment should be selected. Especially for long-distance transportation, it is necessary to prevent high temperature in summer and low temperature in winter to ensure a suitable transportation environment, so that 5-amino-4-cyano-2 - (ethoxycarbonyl) -3-thiophene ethyl acetate can be safely delivered to the destination and maintain its original chemical properties and quality.

What is the market price of 5-Amino-4-cyano-2- (ethoxycarbonyl) -3-thiopheneacetic acid ethyl ester?

Today, there are 5 - Amino - 4 - cyano - 2 - (ethoxycarbonyl) - 3 - thiopheneacetic acid ethyl ester, and its market is rapidly increasing. This is due to the high cost of the market, which is affected by general factors.

First, the supply and demand of this product is the shape of the demand. If the demand is high, and the supply is limited, it will be low; on the contrary, if the supply is high and the demand is limited, there will be a reduction.

Furthermore, the cost of production is also low. The cost of raw materials, the complexity of manufacturing, and the cost of manpower all affect the cost. If the cost is high, the sales price is also low.

In addition, the market is also important. If the market is not occupied, the business will not be determined.

and the situation of the activity of this thing is not, and there is also a problem.


Therefore, if you want to know the market of 5 - Amino - 4 - cyano - 2 - (ethoxycarbonyl) - 3 - thiopheneacetic acid ethyl ester, you can only get the price if you look at the situation of supply and demand, cost, cost, and transportation.

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