5-Acetylthiophene-2-CarboxylicAcid98%

5-Acetylthiophene-2-carboxylic acid (98% content) is a crucial compound in the field of organic synthesis, and its main application range is quite extensive.
In the field of medicinal chemistry, this compound has shown significant value. Due to its unique chemical structure, it can be used as a key intermediate for the synthesis of drug molecules with specific biological activities. For example, in some innovative drug development processes for specific diseases, 5-acetylthiophene-2-carboxylic acid is used as a starting material. After a series of delicate chemical reactions, it can be converted into compounds with high affinity and inhibitory activity for disease targets, making outstanding contributions to human health. < Br >
In the field of materials science, it is also indispensable. It can be introduced into the polymer material structure through chemical modification and polymerization, and then endow the material with novel properties. For example, after special processing, the photoelectric properties of the material can be improved, and it has potential application prospects in the preparation of organic Light Emitting Diode (OLED), solar cells and other optoelectronic devices, helping to optimize the performance and innovation of such materials.
In the field of fine chemicals, it is also an extremely important raw material. It can be used to synthesize many high-end fine chemicals, such as special fragrances, pigments and additives. Taking fragrance synthesis as an example, its participation in the reaction can generate unique aroma components, adding unique products to the fragrance industry; in pigment synthesis, it helps to create pigments with brighter colors and more stable performance, meeting the needs of different industries for high-quality pigments.
In summary, 5-acetylthiophene-2-carboxylic acid plays a key role in many fields such as medicine, materials and fine chemicals due to its unique chemical properties, promoting technological progress and product innovation in various fields.

5-Acetylthiophene-2-carboxylic acid (content 98%), its physical properties are as follows:
This substance is mostly solid at room temperature, and it is usually in the state of white to white crystalline powder. If it is finely crushed ice crystals, it is fine and regular. Its melting point is in a specific range, about 163-167 ° C. When the temperature rises to the melting point, the solid will gradually melt into a flowing state.
In terms of solubility, it shows a certain affinity to organic solvents. For example, in common dichloromethane and chloroform, it can dissolve well, just like ice crystals merging into a warm flow, quietly disappearing, forming a uniform and clear solution. In alcoholic solvents such as methanol and ethanol, it also has a certain solubility, but the degree of solubility may not be as good as that of dichloromethane. However, for water, a highly polar solvent, 5-acetylthiophene-2-carboxylic acid is difficult to dissolve in it, and the two seem to be distinct and difficult to blend, showing obvious layering.
Its density is slightly larger than that of water. If it is placed in water, it will slowly settle to the bottom, like a heavy object sinking. The smell of this substance is weak, close to the smell, only a very light special smell, not pungent and unpleasant smell, but it is also unique and difficult to describe.
This substance is relatively stable under normal conditions, but it may decompose in extreme environments such as hot topics and open flames. Therefore, when storing and using it, it is necessary to pay attention to environmental conditions to avoid being affected by high-temperature hot topics to ensure the stability of its properties.

5-Acetylthiophene-2-carboxylic acid, with a content of 98%. The synthesis methods are as follows.
First, 5-methylthiophene-2-carboxylic acid can be used. First, a suitable oxidant, such as potassium permanganate, is used in an alkaline environment to oxidize the methyl of 5-methylthiophene-2-carboxylic acid to a carboxyl group to obtain 5-carboxylthiophene-2-carboxylic acid. Then this product is acetylated with acetylation reagents such as acetic anhydride and acetyl chloride, and under the catalysis of an appropriate catalyst, such as anhydrous zinc chloride, the acetylation reaction is carried out to obtain 5-acetylthiophene-2-carboxylic acid.
Second, use 2-acetylthiophene as the starting material. First, using a halogenation reaction, such as under the action of light or an initiator, with halogens such as bromine, a halogen atom is introduced at the 5th position of the thiophene ring to obtain 5-halo-2-acetylthiophene. Then, through cyanidation reaction, with cyanidation reagents such as sodium cyanide, the halogen atom is replaced by a cyano group to obtain 5-cyano-2-acetylthiophene. Finally, through hydrolysis reaction, under the catalysis of acid or base, the cyano group is converted into a carboxyl group, and the target product is 5-acetylthiophene-2-carboxylic acid.
Third, the electrophilic substitution reaction of thiophene ring can be used. Taking thiophene as the starting material, the acetyl group is first introduced through the acetylation reaction, and then under appropriate conditions, the carboxylation reagent is reacted with it, and the carboxyl group is introduced at a specific position of the thiophene ring. After reasonable regulation of the reaction conditions and steps, 5-acetylthiophene-2-carboxylic acid can also be synthesized. This process requires attention to the selectivity of the reaction and the control of conditions, so that the reaction proceeds in the expected direction.

5-Acetylthiophene-2-carboxylic acid, with a content of 98%, is difficult to determine within the price range of the market. This is because the price of chemical products is often changeable and subject to various factors.
In the past, the discussion of things in Tiangong Kaiwu and various products changed their values depending on time and place. The same is true for chemical products. The price of 5-acetylthiophene-2-carboxylic acid is primarily related to the price of raw materials. If the raw materials are easy to obtain and abundant in production, the price may be leveled; conversely, if the raw materials are scarce and difficult to purchase, the price will rise.
Secondly, it is related to the production method and process. Sophisticated methods can reduce consumption and production, reduce its cost, and the price is appropriate accordingly; if the process is difficult, time-consuming and labor-intensive, the price will be high.
Furthermore, the situation of market supply and demand is also the main reason. Demand is strong, but the supply is not enough, and the price will rise; if the market is saturated and the supply is excessive, the price will fall.
Moreover, the difference in geography also has an impact. In places with convenient transportation and prosperous chemical industry, the price may be slightly lower due to the convenience of logistics and industrial agglomeration; in remote places, transportation is difficult, and the cost increases, and the price may be higher.
In summary, the 98% content of 5-acetylthiophene-2-carboxylic acid is difficult to determine a certain fixed number at market prices, or in a wide range of tens of yuan per kilogram to hundreds of yuan per kilogram.

5-Acetylthiophene-2-carboxylic acid (content 98%), the way to hide it is related to its nature, so be careful. This is an organic compound, which is active or active, and is quite sensitive to factors such as temperature and humidity of the environment.
Hide it, the first dry place. Cover moisture can easily lead to its qualitative change and damage its purity. It is advisable to choose a cool place to avoid direct sunlight. The energy of sunlight may cause its chemical structure to change, reducing its effectiveness and losing its use.
Furthermore, this substance should be isolated from other substances. Because of its specific chemistry, or phase with neighbors, the reaction is gratuitous. In the place where you hide, you need a well-airtight device to avoid excessive fusion with the air and prevent oxidation and other changes.
Temperature is also necessary. Extremely hot temperatures can promote its decomposition or accelerate the reaction rate; severe cold may cause physical properties to change. Therefore, room temperature or slightly lower degrees, about 15 to 25 degrees Celsius, is the temperature suitable for storage.
And the hiding place should be well ventilated, but do not let the wind be too severe, so as not to evaporate or phase with impurities in the circulating air. Looking at it, store 5-acetylthiophene-2-carboxylic acid in a dry, cool, isolated, temperature-appropriate and ventilated environment to preserve its quality and wait for use.