5 Acetylthiophene 2 Carboxylic Acid
quinoline thiophene imidazole thiazole

5-Acetylthiophene-2-carboxylic acid

Taiy Chemical

    Specifications

    HS Code

    227537

    Chemical Formula C7H6O3S
    Molar Mass 170.186 g/mol
    Appearance Solid (usually white to off - white)
    Melting Point 128 - 132 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, methanol, dichloromethane
    Odor Odorless or faint odor
    Pka Around 3 - 4 (estimated for carboxylic acid group)
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
    Where to Buy 5-Acetylthiophene-2-carboxylic acid in China?
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    Frequently Asked Questions

    As a leading 5-Acetylthiophene-2-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-acetylthiophene-2-carboxylic acid?
    5-Aminotetrazole-2-carboxylic acids are a class of organic compounds that have attracted much attention. Its main uses are quite extensive and it has outstanding performance in many fields.
    In the field of medicinal chemistry, 5-aminotetrazole-2-carboxylic acids are often key intermediates in the synthesis of drugs. The unique structure of the tetrazole ring and carboxyl group endows the compounds with different biological activities and pharmacological properties. With its structural modification and modification, chemists can create drugs with novel mechanisms of action, or to deal with specific diseases, such as certain inflammation-related diseases, with its unique chemical properties, anti-inflammatory drugs can be developed; or for specific bacterial infections, antibacterial drugs can be designed, making great contributions to human health and well-being.
    In the field of materials science, this compound has also emerged. Due to its structural properties, it can participate in the synthesis of polymer materials. For example, when preparing polymers with special properties, 5-aminotetrazole-2-carboxylic acids can be introduced as functional monomers, enabling polymer materials to have better stability, unique optical or electrical properties, etc. In this way, in electronic devices, optical materials, etc., such materials prepared based on this compound are very useful and promote the progress of materials science.
    In agricultural chemistry, 5-aminotetrazole-2-carboxylic acid also shows potential value. It can be used to develop new pesticides, using its chemical structure to inhibit or kill pests or bacteria. At the same time, compared with traditional pesticides, it is expected to have higher selectivity and lower environmental toxicity, which is of great significance for the development of green agriculture.
    In summary, 5-aminotetrazole-2-carboxylic acid, with its unique structure, is an indispensable and important substance in many fields such as medicine, materials, and agriculture, and plays a significant role in promoting the development of various fields.
    What are the physical properties of 5-acetylthiophene-2-carboxylic acid?
    The physical properties of 5-ethylpyridyl pyrimidine-2-carboxylic acid are particularly important. This compound is in the form of a white to light yellow powder, with a fine texture. When viewed in sunlight, it is slightly shiny. Its melting point is about 180-185 degrees Celsius. At this temperature, the substance gradually melts from a solid state to a liquid state, and when it transitions, the state is quite uniform.
    Furthermore, the solubility of 5-ethylpyridyl pyrimidine-2-carboxylic acid is also characteristic. In water, its solubility is very small, only a very small amount can be dissolved, and the solution is slightly cloudy. However, in organic solvents such as dichloromethane, N, N-dimethylformamide, its solubility is quite good, and it can be quickly dissolved to form a clear solution. This solubility property has far-reaching implications in many fields such as chemical synthesis and drug preparation.
    When it comes to density, 5-ethylpyrimidine-2-carboxylic acid is about 1.3-1.4 grams per cubic centimeter, which is higher than the common water density. Its stability is also worth mentioning. Under normal temperature and pressure and dry environment, this compound can maintain a stable state and is not prone to chemical reactions. However, if placed in a high temperature, high humidity or strong acid-base environment, its chemical structure may change, which in turn affects its physical properties. The physical properties of 5-ethylpyridyl pyrimidine-2-carboxylic acid, such as appearance, melting point, solubility, density and stability, are all important characteristics of it, and it plays an important role in scientific research and industrial production.
    What are the chemical synthesis methods of 5-acetylthiophene-2-carboxylic acid?
    To prepare 5-ethyl-2-furanoic acid, the following methods can be used:
    First, start with 5-ethyl-2-furanal and obtain it by oxidation. Aldanes can be oxidized to corresponding acids under suitable conditions by strong oxidizing agents, such as potassium permanganate, potassium dichromate, etc. Mild oxidizing agents can also be used, such as Torun reagent or Feilin reagent, which can selectively oxidize aldehyde groups to carboxyl groups, while other easily oxidized groups in the molecule are not affected. 5-Ethyl-2-furanal is co-heated with Torun reagent, and the aldehyde group is oxidized to a carboxyl group to obtain 5-ethyl-2-furanic acid. This reaction has few side reactions and the product is relatively pure.
    Second, 5-ethyl-2-furan halogen is prepared by carboxylation. First, 5-ethyl-2-furan halogen is interacted with magnesium metal to prepare Grignard reagent. For example, 5-ethyl-2-furan bromide reacts with magnesium in anhydrous ether to obtain 5-ethyl-2-furan magnesium bromide. Then carbon dioxide is introduced and hydrolyzed, that is, carboxyl groups are introduced to generate 5-ethyl-2-furanic acid. In this process, Grignard's reagent has high activity, and the reaction conditions need to be strictly anhydrous, otherwise Grignard's reagent is easy to decompose.
    Third, unsaturated hydrocarbons containing corresponding substituents are used as raw materials and synthesized through a series of reactions such as addition and oxidation. If an unsaturated hydrocarbon with a suitable structure is selected, it is first added with hydrogen halide, introduced into a halogen atom, and then prepared into a Grignard reagent, and then the product is obtained by carboxylation as described above; or the oxidizable group is first added, and then oxidized to form a carboxyl group, and finally 5-ethyl-2-furanoic acid is obtained. This approach is a bit complicated, and the reaction conditions of each step need to be precisely controlled to achieve the purpose of high yield and high selectivity.
    What is the price range of 5-acetylthiophene-2-carboxylic acid in the market?
    5-Ethylamino-2-naphthalic acid is available in the market, and its price range varies with time, place and quality.
    The price of these chemical materials is often determined by the combination of supply and demand, and the quality is good. When its quality is high and the supply is small and the demand is large, the price must rise; if the quality is flat and the supply is excessive, the price may drop.
    According to the past situation and the general market view, the price of 5-ethylamino-2-naphthalic acid is often between a few yuan and tens of yuan per gram. If it is a product of high purity and suitable for fine scientific research or special industries, its price or higher can reach a spectrum of 100 yuan per gram. And for ordinary commercial use, if the quality is relatively average, the price may be slightly lower, and the number of yuan per gram is also common.
    However, the market is impermanent, and the price is indeterminate. The rise and fall of the market and the change of the process can cause the price to fluctuate. Therefore, in order to know the real-time price, it is necessary to carefully consider the current market conditions, consult the industry merchants, brokers, or observe the price listed by the trading platform, and obtain a close-to-real number.
    What are the precautions for 5-acetylthiophene-2-carboxylic acid during storage and transportation?
    5-Ethylbenzyl ether-2-heptanoic acid has many things to pay attention to when storing and transporting. Both are organic compounds with special properties and need to be treated with caution.
    First words storage. First, you should find a cool, dry and well-ventilated place. 5-Ethylbenzyl ether-2-heptanoic acid is prone to chemical changes if heated or wet, and even poses a risk of safety. Due to the flammability of organic compounds, high temperature or humid environment may increase the risk of combustion and explosion. Second, it needs to be stored separately from oxidants, acids, bases, etc. The chemical structure of 5-ethylbenzyl ether-2-heptanoic acid determines that it is easy to cause chemical reactions in contact with these substances, or cause violent reactions, threatening storage safety. Third, the storage container must be well sealed. This can prevent its volatilization and cause high concentration in the environment, which not only damages the environment, but also increases safety hazards; and can avoid its reaction with air components and maintain its chemical stability.
    Second talk about transportation. Before transportation, be sure to ensure that the packaging is complete and firm. Due to bumps and collisions during transportation, if the packaging is not good, 5-ethylbenzyl ether-2-heptanoic acid is easy to leak, pollute the environment, and endanger the safety of transporters and surrounding areas. The means of transportation should also be suitable, and they should have safety facilities such as fire prevention and explosion protection. In view of the organic characteristics of the two, fire prevention and explosion prevention during transportation is crucial. The transportation process should also strictly control the temperature and humidity to avoid changes in the nature caused by the uncomfortable environment. Transport personnel also need professional training, familiar with the characteristics of 5-ethylbenzyl ether-2-heptanoic acid and emergency treatment methods. In case of emergencies, they can respond quickly and properly to minimize harm.