5-(2-sulfanylidene-3H-1,3-thiazol-4-yl)thiophene-2-carboxamide

This is the chemical structure analysis of 5- (2-thionyl-3H-1,3-thiazole-4-yl) thiophene-2-formamide. Looking at its name, this compound is cleverly connected by thiophene and thiazole two structural units. Thiophene, a five-membered heterocycle with conjugated double bonds, has a planar structure and good stability, and is widely used in many fields of organic synthesis and materials science. Thiazole, also a five-membered heterocycle containing sulfur and nitrogen, plays an important role in the field of medicinal chemistry and bioactive substances.
In this compound, the 2-position of thiophene is connected by formamide group, and the carbonyl group and amino group in formamide group are connected in a conjugated form, which has a great impact on the physical and chemical properties of the compound. The thiazole ring is connected to thiophene at the 4-position, and the 2-position of thiazole is substituted by thionyl group. In the thionyl group, the sulfur atom and the oxygen atom are connected by double bonds, giving the molecule a specific electronic effect and spatial structure.
In this structure, the atoms are connected by covalent bonds, and the electron cloud is distributed between the atoms to form a stable structure. The interaction of each group determines the reactivity, solubility and stability of the compound. Due to the existence of the conjugated system of thiazole and thiophene, the compound may have certain optical and electrical properties. The uniqueness of its chemical structure lays the foundation for the exploration of new drugs, materials and other applications, and also opens up new paths for chemical research and industrial applications.

5 - (2 - sulfanylidene - 3H - 1,3 - thiazol - 4 - yl) thiophene - 2 - carboxamide, which is an organic compound. Its main uses are quite extensive, and it is often used as a lead compound in the field of pharmaceutical research and development. Because the specific structure can interact with proteins, enzymes and other targets in the body, researchers can modify and optimize its structure, or develop new therapeutic drugs, such as antibacterial, anti-inflammatory and anti-tumor drugs. In the field of materials science, such sulfur-containing heterocyclic compounds may have unique optoelectronic properties and can be used to prepare organic semiconductor materials, which can be used in organic Light Emitting Diodes (OLEDs), field-effect transistors and other optoelectronic devices to improve their performance and efficiency. In the agricultural field, they may have potential bactericidal and insecticidal activities. After research and development, they may become new pesticides to escort crops and protect them from pests and diseases. And because of their special structure, they can be used as key intermediates in organic synthetic chemistry. Through various chemical reactions, more complex and functional organic molecules can be constructed to promote the development of organic synthetic chemistry.

To prepare 5- (2-thioalkyl-3H-1,3-thiazole-4-yl) thiophene-2-formamide, the method is as follows:
First take an appropriate amount of thiazole precursor, dissolve it in a clean reactor with a specific organic solvent. This organic solvent needs to be selected that is well miscible with the reactants and has no interference with the reaction, such as dichloromethane. Then, add a precisely measured alkali catalyst, such as potassium carbonate, to promote the reaction.
At the same time, another thiophene-2-formamide derivative is prepared and slowly poured into the reactor. During this period, close attention should be paid to the change of the reaction temperature, and it should be controlled in an appropriate range, or about room temperature to 50 degrees Celsius. Fine-tune according to the specific reaction process and the characteristics of the reactants. During the reaction, keep stirring to make the reactants fully contact and accelerate the reaction rate.
After the reaction is completed, the impurities are removed by conventional separation and purification methods, such as column chromatography, to obtain a pure 5- (2-thioalkyl-3H-1,3-thiazole-4-yl) thiophene-2-formamide product. When operating, it is necessary to adhere to the chemical test specifications to ensure safety and accuracy, so that the purity and yield of the product can reach the expected standard.

5 - (2 - thionylalkyl - 3H - 1,3 - thiazole - 4 - yl) thiophene - 2 - formamide, this is an organic compound, its physical and chemical properties are as follows:
- ** Properties **: Under normal conditions, or in a solid state, looking at its color, or in a white to light yellow powder form, due to the arrangement of atoms and chemical bonds in the molecular structure, under the action of light, showing such color and morphology.
- ** Melting point **: The number of melting points, between about 180 - 190 ° C. When the temperature gradually rises to this point, the intermolecular force is destroyed due to the injection of heat energy, the lattice structure disintegrates, and then melts from the solid state to the liquid state.
- ** Solubility **: In water, its solubility is not good, because of its molecular structure, hydrophobic groups account for a large proportion, and it is difficult to form an effective interaction with water molecules. However, in organic solvents such as dichloromethane, N, N-dimethylformamide, it has better solubility, because the molecules of these organic solvents and the compound molecules can form interactions such as van der Waals forces to help it disperse and dissolve.
- ** Stability **: Under normal temperature and environment, it has certain stability. However, in the case of strong acids and bases, sensitive chemical bonds in the molecular structure, such as amide bonds and some bonds on thiazole rings, are vulnerable to attack and hydrolysis or other chemical reactions occur, resulting in structural changes.
- ** Spectral properties **: In the infrared spectrum, at about 3300-3400 cm. Between 1650 and 1700 cm, the stretching vibration absorption peak of the amide N-H bond can be seen, which is the characteristic peak of the amide group; between 1650 and 1700 cm. In hydrogen nuclear magnetic resonance spectroscopy, hydrogen atoms in different chemical environments will exhibit characteristic peaks at corresponding chemical shifts, from which the position and number of hydrogen atoms in the molecule can be inferred.

Guanfu "5- (2-sulfinyl-3H-1,3-thiazole-4-yl) thiophene-2-formamide" is quite hidden in the market. Because it is a specific chemical compound, it is not widely used in the daily market.
However, in the field of scientific research, the field of chemical industry, or the research and development of medicine, its traces can be found. In scientific research, or as a raw material for exploring the properties and reactions of new compounds; in chemical industry, or as an intermediate for the synthesis of fine chemicals; in medicine, or as a cornerstone for the construction of potential drug molecules.
However, its market circulation is unlike that of ordinary commodities. Most of them exist in professional chemical reagent suppliers, and transactions are often limited to professionals and institutions. Buyers need professional knowledge and permission for use in order to obtain it. Because it is common in the public market, it is rarely seen; in the professional field, although there are few people who need it, it is quite useful, and it is indispensable for the progress of related industries.