5-(2-Mercapto-4-thiazolyl)-2-thiophenecarboxamide

5- (2-mercapto-4-thiazolyl) -2-thiophenoformamide is an organic compound. Its main use is in the field of medicinal chemistry and organic synthesis, which has attracted much attention.
In the field of medicinal chemistry, such compounds are often the key components of potential drug molecules. Because their structures contain special thiazole and thiophene groups, they give them unique biological activities. Studies have shown that such structures may have various biological activities such as antibacterial, anti-inflammatory and anti-tumor. For example, in terms of antibacterial, it may interact with specific enzymes or proteins in bacteria to interfere with the normal metabolic process of bacteria and inhibit bacterial growth and reproduction. In the field of anti-tumor, or by regulating the signal transduction pathway of tumor cells, it can induce tumor cell apoptosis, thereby exerting its anti-cancer ability.
In the field of organic synthesis, 5- (2-mercapto-4-thiazolyl) -2-thiophenoformamide is often used as an important synthetic intermediate. Because of its active groups such as amides, mercapto groups and heterocycles, it can participate in many organic reactions. For example, through the formation of amide bonds, it can be combined with different amines or carboxylic acid derivatives to construct more complex organic molecular structures. The thiol group also has high reactivity, which can carry out reactions such as thioetherification and oxidation, which helps to expand the structural diversity of compounds and lays the foundation for the synthesis of novel organic materials or functional molecules.
In summary, 5- (2-mercapto-4-thiazolyl) -2 -thiophenoformamide has important application value and research significance in the fields of medicine and organic synthesis due to its unique structure.

The synthesis of 5- (2-mercapto-4-thiazolyl) -2-thiophenoformamide is a key issue in the field of organic synthesis. Its synthesis path often involves many chemical reaction steps, and each step needs to be carefully controlled to achieve the desired product.
One of the methods may be initiated by thiophene derivatives. First, the thiophene is introduced into the active precursor of the carboxyl group at the 2-position through a specific substitution reaction. In this step, a suitable halogenation reagent can be used to react with the thiophene under suitable reaction conditions, such as a specific temperature and the presence of a catalyst. Halogenation reaction occurs, and then hydrolysis and other steps are taken to obtain 2-thiophene carboxylic acid intermediates.
Subsequently, for the introduction of 2-mercapto-4-thiazolyl, thiazole derivatives containing mercapto groups can be amidated with the obtained 2-thiophene carboxylic acid intermediates under the action of condensing agents. Condensation agents such as dicyclohexyl carbodiimide (DCC) can promote the dehydration of carboxyl groups and amino groups to form amide bonds. During the reaction process, temperature, reaction time and the molar ratio of the reactants are all important factors affecting the yield and selectivity of the reaction.
Another synthesis idea, or starting from the construction of thiazole rings. Using compounds containing sulfur and nitrogen as raw materials, the 2-mercapto-4-thiazolyl-related intermediates were first synthesized through cyclization, and then the intermediates were reacted with thiophene derivatives through suitable ligation reactions to construct the structure of the target product. In this process, the conditions of the cyclization reaction, such as solvent, reaction temperature, catalyst type, etc., need to be carefully optimized to ensure the correct construction of the thiazole ring. When linking the reaction, the appropriate reaction reagents and conditions need to be selected according to the activity of the substrate to achieve efficient synthesis of 5- (2-mercapto-4-thiazolyl) -2-thiophenoformamide.

5- (2-mercapto-4-thiazolyl) -2-thiophenoformamide, this material has quite unique properties. Its appearance is often white to light yellow crystalline powder with fine texture.
When it comes to melting point, it is usually in a relatively high temperature range. This property makes it thermally stable under certain conditions, and it is not easy to melt and deform at ordinary ambient temperatures.
In terms of solubility, it shows a certain solubility in organic solvents, such as common ethanol and acetone, and can be slowly dissolved into it to form a uniform liquid phase. However, the solubility in water is very small, and it is difficult to disperse and dissolve in water. This difference is due to the characteristics of the groups in its molecular structure.
Its density also has a specific value. In the solid state, the molecular arrangement is relatively tight, resulting in a certain range of density, which affects its settlement or suspension state in different media.
In addition, the compound has a certain sensitivity to light and air. Under light conditions, some chemical bonds in its molecular structure are easily excited by photon energy, causing structural changes, which in turn affect its chemical properties. In air, long-term contact with oxygen, water vapor and other components may also cause reactions such as oxidation, resulting in changes in its quality. Therefore, during storage and use, it should be properly sealed and stored in a cool and dark place to maintain its physical stability and ensure its proper performance in subsequent applications.

5- (2-mercapto-4-thiazolyl) - 2-thiophenoformamide, this is an organic compound with specific chemical properties.
Its appearance is often in a solid state, mostly powdery or crystalline. Due to the force between molecules, it maintains a solid state at room temperature and pressure.
In terms of solubility, the compound exhibits certain solubility in organic solvents, such as common organic solvents such as ethanol and dichloromethane, or it can be soluble. However, in water, its solubility or poor, due to the large proportion of hydrophobic groups in its molecular structure, it is difficult to form effective interactions with water molecules. < Br >
In terms of stability, this compound may have certain stability under conventional conditions. In case of extreme conditions such as high temperature, strong acid, and strong base, its structure may be damaged. At high temperature, the vibration of chemical bonds in the molecule intensifies, or the bond is broken; under strong acid and strong base environments, acid-base reactions may be triggered, resulting in molecular structure changes.
Chemical reactivity is also a key property. Because it contains active groups such as thiol and amide groups, thiol groups have strong nucleophilicity and are easy to react with electrophilic reagents, such as reacting with halogenated hydrocarbons to form thioether compounds; although amide groups are relatively stable, under certain conditions, such as high temperature, strong acid or strong base catalysis, hydrolysis can occur to generate corresponding carboxylic acids and amines. At the same time, thiazolyl and thiophene groups, as aromatic heterocyclic structures, can also participate in typical reactions of various aromatic compounds, such as electrophilic substitution reactions. Under suitable conditions, other functional groups can be introduced into the heterocyclic ring.

I look at this "5- (2-mercapto-4-thiazolyl) -2-thiophenoformamide" product, and it is difficult to hide it from the market price. Due to the complicated market conditions, the price is affected by many factors.
First, the purity of this compound has a great impact on the price. If the purity is extremely high, it is almost flawless, and its price is high; on the contrary, if the purity is slightly lower, the price may drop.
Second, the trend of supply and demand is also the key. If there are many people who want it, and the supply is small, the price will rise; if the supply exceeds the demand, the price will fall.
Third, the difficulty of preparation is also related to the price. If the preparation process requires exquisite skills and rare raw materials, the cost is high, and the price is also high; if the preparation is easier, the price may be close to the people.
Also look at the "Tiangong Kaiwu". Although it is an ancient book describing the process technology, it is difficult to find a direct record for the price of this specific compound. The technology of chemical industry at that time has not yet been realized, and such fine compounds may not exist in the world.
To know the exact price of this product today, it is necessary to widely investigate the chemical raw material market, consult merchants, chemical trading platforms, or interview experts in the industry, in order to obtain a more accurate number. However, it is common sense that in the chemical industry, such special compounds fluctuate in a large range due to the characteristics of preparation and use, and the price may fluctuate due to different specifications and qualities. Or there are hundreds of yuan per gram, or the price is higher due to special needs and quality, which is difficult to generalize.