As a leading 4,7-dichloro-1-benzothiophene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4,7-dichloro-1-benzothiophene?
In the field of pharmaceutical synthesis, the function of 4,7-dioxy-1-azabicyclo [3.3.0] octane is particularly critical.
This compound is often used as a key intermediate in the creation of drug molecules. Due to its unique molecular structure, it can endow synthesized drugs with different physical, chemical and biological properties.
In the development of antibacterial drugs, the structure of 4,7-dioxy-1-azabicyclo [3.3.0] octane may optimize the affinity and inhibitory activity of drugs on bacterial cell walls or specific enzymes, resulting in improved antibacterial efficacy. It can precisely fit the bacterial target, just like the joint of mortise and tenon, interfering with the normal physiological metabolism of bacteria, and achieving the purpose of antibacterial.
In the field of antiviral drugs, this compound may enhance the interaction between drugs and viral proteins by modifying drug molecules. Such as changing the spatial conformation of the drug to make it easier to bind to the surface protein of the virus, blocking the path of the virus invading the host cell, thereby inhibiting the replication and spread of the virus.
In the field of neurological drugs, 4,7-dioxy-1-azabicyclo [3.3.0] octane can improve the ability of drugs to pass through the blood-brain barrier by regulating the balance of lipophilicity and hydrophilicity of drug molecules. In this way, drugs can more smoothly reach the targets of the central nervous system, and exert the efficacy of treating neurodegenerative diseases or psychiatric diseases.
In particular, 4,7-dioxy-1-azabicyclo [3.3.0] octane is an indispensable cornerstone in the synthesis of medicine, paving an important path for the creation of efficient and specific new drugs.
What are the physical properties of 4,7-dichloro-1-benzothiophene?
4,7-Dioxo-1-azabicyclic [3.2.0] heptane is an organic compound that is crucial in the field of organic synthesis. The following are brief descriptions of its physical properties:
Its properties are often white to light yellow crystalline powder, which is easy to store and use. In various chemical reactions, the corresponding quality can be accurately weighed according to specific needs.
The melting point is in a specific range, usually between [X] ° C - [X] ° C. As a key physical property, the melting point is of great significance for the identification of its purity. If the substance contains impurities, the melting point tends to decrease and the melting range becomes wider, so the purity status can be quickly determined by melting point measurement.
In terms of solubility, it can be soluble in some organic solvents, such as dichloromethane, N, N-dimethylformamide, etc. This solubility property facilitates its application in organic synthesis reactions, and can be uniformly dispersed in the reaction system with the help of suitable solvents, so that the reaction can be fully carried out. However, the solubility in water is low, and this property can be utilized during product separation and purification, and separation can be achieved by extraction of aqueous and organic phases.
From the perspective of stability, it has certain stability under conventional conditions. However, when encountering extreme conditions such as strong acid, strong base or high temperature, the structure may be damaged and reacted. During storage and use, it is necessary to pay attention to environmental conditions to prevent it from deteriorating due to improper conditions and affecting the use effect. Due to its nitrogen and oxygen heteroatoms, there is a certain force between molecules, which also affects its physical properties, such as boiling point, density, and other properties. Its density is about [X] g/cm ³, and the boiling point is around [X] ° C. These properties are important factors to consider in the separation, identification, and related reaction process design of substances.
Is the chemical properties of 4,7-dichloro-1-benzothiophene stable?
4,7-Dioxo-1-azabicyclo [3.2.0] heptane is stable. It has the structure of a ring system, and the oxygen and nitrogen atoms in the ring are distributed at a specific location to form a stable structure. The tension of the ring is moderate, and it does not cause high activity and easy decomposition due to high tension.
From the perspective of covalent bonds, the atoms in the molecule are connected by covalent bonds. Covalent bonds such as carbon-carbon, carbon-hydrogen, carbon-oxygen, and carbon-nitrogen have a certain bond energy. Those with higher bond energy make the corresponding chemical bonds in the molecule difficult to break and increase molecular stability. Such as carbon-carbon single bonds, the bond energy is considerable, and it is difficult to spontaneously break under normal conditions, resulting in molecular structure changes.
and the electron cloud distribution of the surrounding atomic groups also affects the stability. Oxygen, nitrogen and other atoms have certain electronegativity. When bonding with neighboring atoms, the electron cloud is biased towards electronegative large atoms, so that the local charge distribution is relatively stable. This stable state of charge distribution reduces the tendency of molecules to initiate reactions due to uneven charges, thereby enabling 4,7-dioxo-1-azabicyclo [3.2.0] heptane to maintain a stable structure under normal conditions, and is not prone to chemical reactions that cause changes in its own structure.
However, it should be noted that physical stability is a relative concept. In case of specific conditions, such as high temperature, strong oxidants, strong acids and bases, its structure or stability will also be affected, and corresponding chemical reactions will occur.
What are the synthesis methods of 4,7-dichloro-1-benzothiophene?
The synthesis method of 4,7-dihydroxy-1-naphthopyran is not directly described in the system of Tiangongkai, but it can be deduced from the ancient chemical process ideas and the preparation of similar substances.
Ancient alchemy and alchemy have explored the transformation and synthesis of substances. To make 4,7-dihydroxy-1-naphthopyran, you can start from natural naphthalene-containing substances. The ancients were good at extracting materials from grass, wood and gold stones, or they could find plants rich in naphthalene rings, such as some coniferous plant extracts, which were specially treated to obtain the basic structure of naphthalene.
The method of introducing hydroxyl groups can be analogous to the ancient oxidation process. In ancient times, strong oxidants such as saltpeter were used for oxidative modification of substances. It is possible to try to treat the initial naphthalene-containing compounds with mild oxidants to introduce hydroxyl groups at specific positions. If etalite and saltpeter are compatible in a certain proportion, under appropriate temperature and reaction environment, the hydroxylation of naphthalene rings at specific positions may be realized, and 4,7-dihydroxynaphthalene derivatives can be obtained.
As for the construction of pyran rings, the ancient cyclization process can be imitated. In ancient times, organic acids were used to catalyze the formation of intramolecular rings. Here, natural organic acids, such as acetic acid, citric acid, etc., can be used to promote the reaction of dihydroxyl naphthalene derivatives with appropriate aldehyde or ketone substances under heating and appropriate media. 4,7-dihydroxyl-1-naphthalene is formed by condensation cyclization.
In addition, the control of the reaction environment and conditions is crucial. The ancients knew well that the influence of heat and time on the reaction. In this synthesis, the heating temperature, duration and pH of the reaction system need to be precisely controlled. Heating with charcoal fire is timely adjusted according to the color and temperature changes of the flame. At the same time, the pH of the system is adjusted with water, vinegar, etc., so that the reaction proceeds in the direction of generating the target product. In this way, the synthetic path of 4,7-dihydroxy-1-naphthopyran can be explored.
What is the price of 4,7-dichloro-1-benzothiophene in the market?
In today's market, the price of 4,7-dioxy-1-azabicyclo [3.2.0] heptane varies from time to time, from quality to quality, and the market is complex, making it difficult to determine the value.
However, the approximate price of this product is related to various reasons. First, it is difficult to make, if the preparation is complicated, the materials used are rare, and exquisite methods and precious materials are required, then the price will be high; second, in the situation of demand and supply, if there are many people and few people to supply, the thing is rare and expensive, and the price will rise; on the contrary, if the supply exceeds the demand, the price will decline. Third, the quality is good or bad, the quality is pure and flawless, and the price should be higher than the one containing miscellaneous.
In the past, in a certain place at a certain time, the high quality of 4,7-dioxy-1-azabicyclo [3.2.0] heptane, due to the difficulty of preparation and the large number of applicants, the price can reach a high level; and in other places, or due to the improvement of the preparation method, the supply is gradually abundant, and the price is also reduced.
To know the exact market price, you need to go to the pharmaceutical and chemical industries in person, consult the merchants, carefully observe the quality, and measure the supply and demand, in order to get a more accurate price. Don't listen to biases, when many parties research, so that you can know the price in the market.