3 Thiophenemethanamine
quinoline thiophene imidazole thiazole

3-thiophenemethanamine

Taiy Chemical

    Specifications

    HS Code

    863331

    Chemical Formula C5H7NS
    Molar Mass 113.18 g/mol
    Appearance Colorless to light yellow liquid
    Boiling Point 217 - 218 °C
    Melting Point N/A
    Density 1.117 g/cm³
    Solubility In Water Slightly soluble
    Flash Point 98 °C
    Odor Aminic, somewhat sulfurous
    Pka N/A
    Refractive Index 1.568

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    General Information
    Where to Buy 3-thiophenemethanamine in China?
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    Frequently Asked Questions

    As a leading 3-thiophenemethanamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-thiophenomethylamine?
    Ethyl 3-pentanoate, also known as beta-pentanoate, has a wide range of main uses. In the field of organic synthesis, this is a crucial raw material.
    In terms of the preparation of drugs, the synthesis path of many drugs often relies on ethyl 3-pentanoate. For example, in the synthesis of some antipyretic and analgesic drugs, it can act as a key intermediate. With specific chemical reaction steps, ethyl 3-pentanoate can gradually build a complex drug molecular structure through the transformation and modification of functional groups, which in turn endows the drug with specific pharmacological activity.
    Ethyl 3-pentanoate also plays an indispensable role in the synthesis of fragrances. Due to its unique chemical structure, through appropriate reaction and preparation, compounds with pleasant aroma can be generated. For example, when blending certain floral or fruity fragrances, it can add unique flavor and layering to the fragrance, making the aroma richer and more attractive.
    Furthermore, in the field of dye synthesis, ethyl 3-pentanoate also plays an important role. Through a series of organic reactions, it can be converted into compounds containing specific chromogenic groups, which can be used in the preparation of dyes. The obtained dyes have a wide range of uses in textile, printing and dyeing industries, and can endow fabrics with rich and diverse colors. In conclusion, ethyl 3-pentanoate plays a key role in many branches of organic synthesis due to its unique chemical properties, providing an indispensable starting material and intermediate for the preparation of many fine chemicals.
    What are the physical properties of 3-thiophenomethylamine?
    3-Nitrate-sulfur-based compound fertilizers are commonly used in chemical fertilizers and have many unique physical properties.
    Its appearance is usually granular, the particles are uniform and round, and the surface is smooth. This shape is conducive to uniform distribution in the soil, and it is easy to mechanically sow, which greatly improves the fertilization efficiency. Looking at its color, it is mostly white or off-white, with pure color and no variegation, showing its high purity from the appearance.
    In terms of its density, it is moderate and stable. In this way, it is not easy to break due to excessive accumulation during storage and transportation, which can effectively maintain the integrity of the particles and ensure the stability of the fertilizer effect. Its hygroscopicity is relatively low, and it is not easy to get wet and agglomerate in an environment with high air humidity, which greatly facilitates storage and use, and farmers do not need to worry about fertilizer deterioration due to poor storage conditions.
    In addition, 3-nitrosulfide compound fertilizer has good solubility. After applying it to the soil, it can dissolve quickly in contact with water, and the nutrients contained in it can be released quickly, which can be absorbed and utilized by the root system of crops. During the critical period of crop growth, it can replenish the required nutrients in time, effectively ensuring the strong growth of crops.
    Furthermore, the chemical properties of the compound fertilizer are relatively stable. Under general storage conditions, it is not easy to chemically react with other substances. It can be mixed with a variety of pesticides and fertilizers, providing great convenience for the fertilization operation in agricultural production. It can reduce the fertilization process and save manpower and material resources.
    To sum up, 3-nitrosulfide compound fertilizers play an important role in agricultural production due to their uniform appearance, moderate density, low hygroscopicity, good solubility and stable chemical properties, and are favored by the majority of farmers.
    Is the chemical property of 3-thiophenomethylamine stable?
    Ethyl 3-chloropropionate is an organic compound. Its chemical properties are stable to a certain extent, but it can also react under specific conditions.
    From a structural point of view, ethyl 3-chloropropionate contains chlorine atoms and ester groups. The ester group is more active and can be hydrolyzed in case of acid or base. In an acidic medium, the hydrolysis reaction proceeds slowly to generate 3-chloropropionic acid and ethanol; under alkaline conditions, the hydrolysis reaction is easier and faster, and the base can catalyze the breaking of ester bonds to generate 3-chloropropionate and ethanol.
    The chlorine atom is also the active check point. In the nucleophilic substitution reaction, the chlorine atom can be replaced by other nucleophilic reagents. In case of nucleophiles such as sodium alcohol, chlorine atoms can be replaced by alkoxy groups to form new ester compounds.
    However, at room temperature and pressure without the action of specific reagents, ethyl 3-chloropropionate is relatively stable and can be stored in the general environment for a period of time without significant deterioration. However, it should be noted that because of its certain chemical activity, it should be stored away from high temperature, open flame and strong acid and alkali conditions that may initiate reactions to prevent danger or cause changes in its chemical properties.
    What are the synthesis methods of 3-thiophenomethylamine?
    3-Ethyl cyanopropionate is an important intermediate in organic synthesis, and its synthesis methods are diverse. The following are the common ones:
    1. ** Knoevenagel condensation reaction **: Diethyl malonate and formaldehyde are used as starting materials. In the presence of weakly basic catalysts such as pyridine and hexahydropyridine, the two undergo a condensation reaction to form diethyl methylene malonate, which is then cyanidated by sodium cyanide to obtain ethyl 3-cyanopropionate. This reaction condition is mild, the operation is relatively simple, and the yield is quite high. However, the raw material diethyl malonate is slightly more expensive, and the cost may be affected. The reaction process is as follows:
    -Diethyl malonate and formaldehyde are first condensed under the action of a catalyst. The active methylene in diethyl malonate reacts with the carbonyl group of formaldehyde to form a carbon-carbon double bond to form diethyl methylene malonate.
    -Next, diethyl methylene malonate reacts with sodium cyanide, and the cyano group replaces one of the ester groups. Ethyl cyanopropionate is finally formed.
    2. ** Michael Addition Reaction **: Using ethyl acrylate and sodium cyanide as raw materials, in the presence of appropriate solvents and catalysts such as quaternary ammonium salts, the cyano group of sodium cyanide undergoes Michael addition reaction to the carbon-carbon double bond of ethyl acrylate to obtain ethyl 3-cyanopropionate. This method is relatively common in raw materials and has relatively low cost, but the reaction conditions need to be strictly controlled to ensure the safe use of sodium cyanide and the smooth progress of the reaction. The reaction steps are:
    - In the solvent, the quaternary ammonium salt catalyst promotes the dissociation of negative cyanide ions from sodium cyanide. < Br > -Cyanoanion as a nucleophilic reagent attacks the carbon-carbon double bond of ethyl acrylate, and Michael addition occurs to generate ethyl 3-cyanopropionate.
    3. ** Reformatsky reaction **: Ethyl bromoacetate and zinc powder are made into organozinc reagent, and then Reformatsky reaction with propionaldehyde to generate β-hydroxy ester. After dehydration and cyanidation steps, ethyl 3-cyanopropionate can be prepared. This method is slightly complicated, but it can effectively construct carbon-carbon bonds, providing a choice for the synthesis of ethyl 3-cyanopropionate with specific structures. The specific process is as follows:
    -Ethyl bromoacetate reacts with zinc powder in anhydrous ether and other solvents to form an organozinc reagent, which has high activity.
    -Organozinc reagent and propionaldehyde undergo nucleophilic addition to form β-hydroxylate intermediates.
    -The intermediate is dehydrated to eliminate hydroxyl groups to form carbon-carbon double bonds, and then cyanide is reacted to introduce cyano groups, and finally obtain the target product 3-ethyl cyanopropionate.
    What should be paid attention to when storing and transporting 3-thiophenomethylamine?
    3-Pentyleneacetic acid is an organic compound. When storing and transporting it, pay attention to the following things:
    First, when storing, choose a cool and ventilated warehouse. Because of its volatility, high temperature and unventilated places are prone to gas accumulation, increasing the risk of fire and explosion. And the warehouse temperature should be controlled within an appropriate range. Generally speaking, it should not exceed 30 ° C to prevent it from evaporating too quickly or causing chemical reactions due to temperature.
    Second, keep away from fires and heat sources. 3-Pentyleneacetic acid is a flammable substance, and it is easy to burn or even explode in case of open flames and hot topics. Therefore, fireworks are strictly prohibited around the warehouse, and explosion-proof types are also required for electrical equipment to prevent spark ignition.
    Third, it should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed. Due to its active chemical properties, contact with oxidants can cause severe oxidation reactions, and reactions with acids and bases may change their chemical structure, even causing danger.
    Fourth, when transporting, the vehicle used must meet the transportation standards for dangerous goods. The carriage should have good ventilation, heat insulation, rain protection and other properties to prevent its properties from changing due to sun exposure and rain.
    Fifth, during transportation, ensure that the container does not leak, collapse, fall, or damage. After the leakage of 3-pentene acetic acid, volatile gases or polluted air, liquids flow or pollute soil and water bodies, and it is more likely to cause accidents in case of fire sources after leakage.
    Sixth, transportation personnel need to be professionally trained to be familiar with the dangerous characteristics and emergency treatment methods of 3-pentene acetic acid. In the event of an accident during transportation, such as leakage, fire, etc., it can be dealt with quickly and correctly to reduce the harm.