What is the chemical structure of 3-Thiophenecarboxylic acid, 4- (isocyanatosulfonyl) -5-methyl-, methyl ester

This is the problem of organic compounds. To know the chemical structure of 3-thiophenecarboxylic acid, 4- (isocyanate sulfonyl) -5-methyl-, methyl ester, we should analyze it from its naming.

"3-thiophenecarboxylic acid" indicates that this compound has a thiophene ring as the basic structure, and has a carboxyl group at the 3rd position of the thiophene ring. "Methyl ester", that is, the carboxyl group is esterified with methanol to form the structure of -COOCH.

And "4- (isocyanate sulfonyl) -5-methyl-" indicates that isocyanate sulfonyl (-SO ² NCO) is connected at the 4th position of the thiophene ring, and methyl (-CH ²) is connected at the 5th position.

In summary, the chemical structure of this compound is: on the thiophene ring, the 3rd position is connected - COOCH, the 4th position is connected - SO -2 NCO, and the 5th position is connected - CH. In this way, the chemical structure of the compound is clearly presented.

What are the main uses of 3-Thiophenecarboxylic acid, 4- (isocyanatosulfonyl) -5-methyl-, methyl ester

3-Thiophenecarboxylic acid, 4- (isocyanate sulfonyl) -5-methyl-, methyl ester This substance has a wide range of uses. In the field of pharmaceutical chemistry, it is often a key intermediate for the creation of new drugs. The unique structure of Gainthiophene gives it a variety of biological activities. By ingeniously combining with isocyanate sulfonyl and methyl ester groups, many compounds with specific pharmacological effects can be derived, or can be used to develop new anti-disease drugs, such as anti-tumor and anti-infection genera.

In the field of materials science, it also has its uses. It can participate in the preparation of special functional materials. Through chemical reactions, the substance is introduced into the polymer material structure, or the physical and chemical properties of the material can be improved, such as enhancing the stability of the material and adjusting its solubility, so that the material exhibits unique properties in a specific environment to meet the needs of high-end materials.

In the field of organic synthesis, it is an important synthetic building block. Because its functional groups are highly reactive, it can carry out various organic reactions according to different reaction conditions and reagents, such as nucleophilic substitution, addition reactions, etc., to build complex organic molecular structures, providing rich strategies for organic synthesis chemists to help create organic compounds with novel structures and unique functions, and then promoting the progress and development of organic synthesis chemistry.

What is the synthesis method of 3-Thiophenecarboxylic acid, 4- (isocyanatosulfonyl) -5-methyl-, methyl ester

There are currently 3-thiophenecarboxylic acid, 4- (isocyanate sulfonyl) -5-methyl-, methyl ester. To make it, the method is as follows.

First, take an appropriate starting material. This starting material needs to contain a thiophene ring structure, and reserve a reactive functional group at a suitable position for subsequent introduction of the desired substituent.

Based on a compound containing a thiophene ring, a group that can be converted into an isocyanate sulfonyl group is introduced at the 4th position, and a methyl group is introduced at the 5th position. The method of introducing methyl groups can choose suitable methylation reagents, such as iodomethane, etc. Under the catalysis of alkali, through nucleophilic substitution reaction, the methyl group is connected to the 5 position of the thiophene ring.

As for the introduction of isocyanate sulfonyl at the 4 position, the sulfonyl chloride group can be introduced first. Commonly used sulfonating reagents such as chlorosulfonic acid react with the thiophene ring and introduce the sulfonyl chloride group at the 4 position. Then, the sulfonyl chloride reacts with reagents such as silver isocyanate and replaces to obtain the isocyanate sulfonyl group.

Wait until the 4 and 5 substituents on the thiophene ring are introduced properly, and then perform an ester reaction. The thiophene derivative containing carboxyl groups is mixed with methanol, and an appropriate amount of concentrated sulfuric acid is added as a catalyst to heat and reflux. During this process, the carboxyl groups are esterified with methanol to form 3-thiophenecarboxylic acid, 4- (isocyanate sulfonyl) -5-methyl-, methyl ester. After the reaction is completed, the pure target product can be obtained through separation and purification methods such as extraction, distillation, recrystallization, etc.

What are the physical properties of 3-Thiophenecarboxylic acid, 4- (isocyanatosulfonyl) -5-methyl-, methyl ester

3-Thiophenecarboxylic acid, 4- (isocyanate sulfonyl) -5-methyl-, methyl ester This substance has a rather specific behavior. Its shape is often crystalline, and its color is nearly pure white, or slightly colored. At room temperature, this substance is stable and self-sustaining, but if it is heated, its properties change. When heated gradually, to a certain temperature, it slowly melts and turns into a liquid.

Its solubility is also specific. In common organic solvents, such as ethanol and acetone, it can be dissolved quite well, but when it is added, it gradually melts and becomes confused. However, in water, it is difficult to dissolve. If it is placed in water, it is as distinct as oil floating in water.

Its melting point is also fixed. After precise measurement, it is within a certain temperature range. This temperature is the critical point of its conversion from solid to liquid. As for the boiling point, under specific pressure conditions, it also has an exact value. However, if the pressure changes, its boiling point will also change.

And the density of this thing is unique compared with ordinary things. The force between its molecules makes itself arranged in space, so that its density is different from other things. And its refractive index, if measured by light, under a specific wavelength of light, also shows a specific value, which is related to its own molecular structure and electron cloud distribution, and is also a manifestation of its physical properties.

3-Thiophenecarboxylic acid, 4- (isocyanatosulfonyl) -5-methyl-, methyl ester market prospects

Guanfu 3-thiophenecarboxylic acid, 4- (isocyanate sulfonyl) -5-methyl-, methyl ester is of great value in the prospect of the market.

In today's world, the chemical industry is booming, and the demand for fine chemicals is increasing day by day. This compound may be very useful in the field of organic synthesis. Because of its unique structure, it may be used as a key intermediate to prepare many materials with special properties. For example, in the synthesis of new polymer materials, it may participate in the reaction and endow the material with unique electrical, optical or mechanical properties, which will have broad applications in the frontier scientific and technological fields such as electronics and optics.

Furthermore, in the field of medicinal chemistry, it may also hide mysteries. Using it as a starting material, through ingenious chemical modification and transformation, it may be possible to create compounds with novel pharmacological activities, providing a new opportunity for the development of new drugs, and adding to the road to conquering difficult diseases.

Looking at its market prospects, it is not without challenges. The process of synthesizing this compound may need to be refined and optimized. If a more efficient and green synthesis path can be found, production costs can be reduced, and product purity can be improved, its competitiveness in the market will be enhanced. And its related toxicological data and Environmental Impact Assessment also need to be further explored. Only by ensuring its safety and environmental friendliness can it be smooth in the market.

In summary, 3-thiophenecarboxylic acid, 4- (isocyanate sulfonyl) -5-methyl -, and methyl ester face challenges, but they have great potential in the fields of organic synthesis and medicinal chemistry. With time and careful study, they will be able to bloom and occupy a place in the market.