3 Thiophenecarboxylic Acid 2 Bromo
quinoline thiophene imidazole thiazole

3-Thiophenecarboxylic acid, 2-bromo-

Taiy Chemical

    Specifications

    HS Code

    689115

    Chemical Formula C5H3BrO2S
    Molar Mass 207.04 g/mol
    Appearance Solid (usually white or off - white)
    Melting Point 130 - 132 °C
    Boiling Point Decomposes before boiling
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Pka Value Around 3 - 4 (estimated for carboxylic acid group)
    Odor Typical organic acid - like odor, pungent
    Stability Stable under normal conditions, but sensitive to strong reducing agents and bases

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    General Information
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    Frequently Asked Questions

    As a leading 3-Thiophenecarboxylic acid, 2-bromo- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-bromo-3-thiophenecarboxylic acid?
    As recorded in "Tiangong Kaiwu", mirabilite and simple nitrate have a wide range of main uses.
    Mirabilite, salty, bitter, cold in nature, has the effect of laxative, moisturizing dryness and softening, clearing fire and reducing swelling. In the field of medicine, it is often a laxative, which can treat heat stagnation and dry stools. In case of gastrointestinal heat accumulation, dry feces and internal knots, causing abdominal distension and pain, and blocked stools, mirabilite can moisturize dryness and soften, make dry feces go down, and the stomach and intestines are unobstructed. In the case of swelling and toxicity of sores, external use of mirabilite can clear fire and reduce swelling, relieve redness, swelling and heat pain.
    Simple nitrate, similar to the composition of mirabilite In the industrial field, simple nitrate is an important chemical raw material used in the manufacture of glass, ceramics, etc. In the ancient salt making process, simple nitrate can help the crystallization of salt and improve the quality of salt. In the printing and dyeing industry, it is also used to help dyes better adhere to fabrics, making dyeing uniform and firm.
    The records of the uses of the two in "Tiangong Kaiwu" reflect the ancient people's in-depth understanding of material characteristics and applications. This understanding not only promoted the development of medicine, industry and other industries at that time, but also provided valuable experience and foundation for research and practice in related fields in later generations.
    What are the physical properties of 2-bromo-3-thiophenecarboxylic acid
    The 3 + -mercury-3 + -methyl stearate has various physical properties. Mercury is a liquid metal at room temperature, with a silver-white luster, heavy weight and good fluidity, high density, about 13.59 grams/cubic centimeter, and the melting point is extremely low, only -38.87 ° C, and the boiling point is 356.6 ° C. Mercury has a high surface tension, can form spherical droplets on a plane, and has good electrical conductivity. However, it is also toxic, and can be caused by vapor inhalation or skin contact.
    As for methyl stearate, it is a white solid at room temperature and has a fine texture. The melting point is about 39-41 ° C and the boiling point is 215-225 ° C (100 mmHg). It is insoluble in water, but soluble in organic solvents such as alcohols, ethers, and chloroform, with a density of about 0.86-0.88 g/cm3. Methyl stearate has good stability and is not easy to react chemically under normal conditions.
    Of these two, mercury is different from common substances due to its unique liquid metal properties and toxicity; methyl stearate is unique in organic compounds due to its solubility in organic solvents and specific melting points and boiling points. The physical properties of the two are significantly different, and they each play a role in different fields. Mercury is often used in instrument manufacturing, etc. Methyl stearate is more commonly used in lubricants, plasticizers, and other industries.
    Is the chemical properties of 2-bromo-3-thiophenecarboxylic acid stable?
    Guanfu 2 + -cyanogen-3-glutaric acid, which is one of the organic compounds. The stability of its chemical properties needs to be investigated in detail.
    Cyanyl group, with strong electronegativity, often induces electron effects in molecules. The presence of cyanyl groups in 2 + -cyanogen-3-glutaric acid makes the molecular electron cloud distribution unique. It may change the acidity of the carboxyl group. Due to the electron absorption of the cyanyl group, carboxyl hydrogen can be more easily dissociated. However, the electron cloud density of the active part of the molecule decreases, and it may be inert during electrophilic reactions.
    The glutaric acid part, which has the general properties of diacids, can form salts with bases and esters with alcohols. However, the introduction of cyanyl groups makes the reaction activity different from that of ordinary glutaric acid. Cyanyl groups can participate in various reactions, such as hydrolysis to obtain carboxyl groups. Under specific conditions, this process may affect the stability of 2 + -cyano-3-glutaric acid.
    In terms of thermal stability, the interaction between cyanyl groups and carboxyl groups may make the molecular thermal decomposition temperature different from that of ordinary diacids. At high temperatures, the cyanyl group may be removed first, or rearranged with carboxyl groups, resulting in molecular structure changes and loss of stability.
    The solvent environment is also critical. In polar solvents, the cyanyl group and carboxyl group can form hydrogen bonds or electrostatic interactions with solvent molecules, or increase molecular stability; in non-polar solvents, the intermolecular forces are different, or the current aggregation state affects its chemical behavior and stability.
    In summary, the chemical stability of 2 + -cyano3-glutaric acid is not determined by a single factor. The interaction of cyanyl group and carboxyl group, and external conditions such as temperature and solvent have an impact, and its stability cannot be generalized. It must be investigated according to the specific situation and reaction.
    What are the synthesis methods of 2-bromo-3-thiophenecarboxylic acid
    To prepare 2-3-methoxybenzoic acid, there are various methods. One can be separated from natural substances, but this method is often limited by the scarcity of raw materials and the difficulty of extracting.
    Common in the way of chemical synthesis. It can be started from the corresponding phenols and methoxylated to introduce methoxy groups. If you start with catechol and dimethyl sulfate under alkali catalysis, you can get 3-methoxy-1,2-catechol. This step requires controlling the ratio of reaction temperature, time and material to ensure that the reaction is moderate and side reactions are avoided. < Br >
    Then, after carboxylation reaction, add carboxyl group to the appropriate check point. Using carbon dioxide as the carboxyl source, under specific solvents and catalysts, such as in pyridine, catalyzed by copper salts, 3-methoxy-1,2-benzene can be carboxylated to obtain 2-3-methoxybenzoic acid. However, this process requires strict reaction conditions, and temperature and pressure need to be precisely regulated.
    There are also those who use halogenated aromatics as raw materials. Pre-halogenated aromatics and metal reagents, such as magnesium, are made into Grignard reagents, and then reacted with carbon dioxide to introduce carboxyl groups. After methoxylation and hydroxylation, a series of reactions are carried out to obtain the target product. Although this route is complicated, the raw materials are easy to obtain, and if the reaction of each step can be optimized, it is also of practical value.
    In the process of synthesis, each step needs to carefully observe the reaction conditions, reagent selection and product purification, in order to obtain high-purity 2-3-methoxybenzoic acid to meet the needs of all parties.
    What is the price range of 2-bromo-3-thiophenecarboxylic acid in the market?
    In today's market, it is very difficult to determine the price of mercury and benzoic acid, and their prices often change with time and place. Mercury is a kind of spiritual and widely used, and has its uses in medical and industrial technology. In the past, its price fluctuated from time to time due to changes in supply and demand, and the abundance of the origin. However, today, the market situation is complicated, and it is difficult to determine the range of its price.
    As for benzoic acid, it is also a widely used thing, which is involved in medicine and food. The change in its price also depends on the supply of raw materials, the simplicity and complexity of the manufacturing process, and the amount of market demand.
    If you want to know the exact price of the two at the moment, you can get the near-real price when you consult the pharmaceutical companies, city officials, or watch the reports and price lists of the merchants. And the market conditions are changing rapidly, so you should pay attention to the changes in their prices at any time.