3 Methylthio Thiophene
quinoline thiophene imidazole thiazole

3-(Methylthio)thiophene

Taiy Chemical

    Specifications

    HS Code

    662597

    Chemical Formula C5H6S2
    Molecular Weight 130.23
    Appearance Liquid
    Odor Characteristic sulfur - like odor
    Boiling Point Around 180 - 185 °C
    Density 1.19 g/cm³ (approximate)
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Flash Point Approx. 63 °C

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    General Information
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    Frequently Asked Questions

    As a leading 3-(Methylthio)thiophene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3- (Methylthio) thiophene?
    3- (methylthiothiophene) thiophene has a wide range of uses. In the field of organic synthesis, it is an important building block. With its unique structure, it can participate in many reactions and build complex organic molecules.
    First, in pharmaceutical chemistry, it is often a key intermediate for synthesizing drugs. Gai can impart specific biological activities to compounds because of its structure, which helps to develop drugs with novel curative effects. For example, in the creation of some antibacterial and antiviral drugs, 3- (methylthiothiophene) thiophene plays a significant role. Chemists modify and derive compounds with better pharmacological properties.
    Second, in the field of materials science, it also has extraordinary performance. Can be used to prepare organic optoelectronic materials. Due to its conjugated structure and sulfur atom properties, it can affect the electrical and optical properties of materials. The materials made from it can improve their properties in organic Light Emitting Diode (OLED), organic solar cells and other devices, such as enhancing luminous efficiency, improving energy conversion efficiency, etc.
    Furthermore, in the synthesis of fine chemicals, it is also a common raw material. Can make fragrances, dyes, etc. Because of its unique odor and color characteristics, it can add a unique flavor to fragrances and give bright colors to dyes. For example, some high-end fragrances, 3- (methyl thiogeneration) thiophene participates in the synthesis, making its aroma rich; some new dyes, because of their participation, have a brighter and longer-lasting color. From this perspective, 3- (methylthiothiophene) plays an important role in various fields and is an indispensable substance for chemical synthesis and material preparation.
    What are the physical properties of 3- (Methylthio) thiophene
    3 - (methylthiophene) thiophene is an organic compound with unique physical properties. It is liquid at room temperature, and it may be colorless to light yellow in appearance, and has a certain volatility, and a special smell can be smelled in the air.
    The boiling point of this substance is about 190-191 ° C, and the boiling point is not low. Due to the existence of a certain force between molecules, more energy is required to convert it from liquid to gaseous. The melting point is about -48 ° C. It is solid at low temperatures, and melts into a liquid state when the temperature rises slightly.
    3 - (methylthiophene) thiophene has a higher density than water. If mixed with water, it will sink to the bottom of the water. In terms of solubility, it is slightly soluble in water. Due to the fact that water is a polar molecule, the polarity of the compound is relatively small, and it is difficult to dissolve in water according to the principle of "similar miscibility"; but it is soluble in a variety of organic solvents, such as ethanol, ether, dichloromethane, etc., because of its interaction with organic solvent molecules, it is conducive to mutual dissolution.
    In addition, 3 - (methylthio) thiophene has certain stability and can exist stably under normal conditions. However, when encountering specific chemical reagents such as strong oxidizing agents, strong acids, and strong bases, chemical reactions will occur. Because of its structure, thiophene rings and methylthio groups can participate in various reactions and exhibit specific chemical activities.
    What are the chemical properties of 3- (Methylthio) thiophene
    3- (methylthio) thiophene is a member of the family of organic compounds. Its molecular structure has a methylthio group attached to one side of the thiophene ring. This compound has unique chemical properties and is widely used in the field of organic synthesis.
    In terms of physical properties, 3- (methylthio) thiophene is in a liquid state under normal conditions, has a specific odor, and shows a certain solubility in organic solvents.
    In terms of chemical properties, its thiophene ring is aromatic and can participate in electrophilic substitution reactions. Because the thiophene ring is an electron-rich system, it is quite attractive to electrophilic reagents. For example, during halogenation reactions, electrophilic reagents are prone to attack thiophene rings and generate halogenated products.
    Methylthiophene has a significant effect on the reactivity. It is the power supply group, which can increase the electron cloud density of the thiophene ring, making the electrophilic substitution reaction on the ring more likely. Moreover, the sulfur atom in the methylthio group has a lone pair of electrons, which can be used as a nucleophilic check point to participate in nucleophilic reactions, such as reacting with halogenated hydrocarbons to form new sulfur-containing compounds.
    In oxidation reactions, 3- (methylthio) thiophene or methylthio groups exist, showing special oxidation properties. Sulfur atoms can be oxidized to form sulfoxides or sulfone derivatives, which can significantly change the physical and chemical properties of the compounds.
    In the reduction reaction, under specific conditions, thiophene rings or methylthio groups can be reduced to form products with different structures, providing the possibility for the synthesis of various organic compounds.
    3- (methylthio) thiophene has rich chemical properties, which make it a key intermediate in many fields such as pharmaceutical chemistry and materials science, helping scientists create new functional materials and drug molecules.
    What are the preparation methods of 3- (Methylthio) thiophene
    There are several common methods for preparing 3- (methylthio) thiophene.
    One is to use thiophene as the starting material. Thiophene is first sulfonated and a sulfonic acid group is introduced to form a thiophene sulfonic acid derivative. This derivative undergoes nucleophilic substitution reaction with methyl mercaptan under suitable conditions, and the sulfonic acid group is replaced by methyl thiophene to obtain 3- (methylthio) thiophene. During the reaction, it is necessary to pay attention to the reaction temperature, the proportion of reactants and other factors. Too high or too low temperature may affect the reaction process and product yield.
    Second, it can start from sulfur-containing organic compounds. For example, some sulfur-containing halogenated hydrocarbons and thiophene derivatives are catalyzed by metal catalysts such as palladium and nickel to form carbon-sulfur bonds through coupling reactions. During this process, the activity of the catalyst and the selection of ligands are crucial, and appropriate catalysts and ligands can improve the selectivity and efficiency of the reaction.
    Furthermore, using the active hydrogen on the thiophene ring to pull hydrogen with a strong base to generate thiophene negative ions, and then nucleophilic substitution with methyl thiohalides can also obtain 3- (methyl thiohalides) thiophene. In this process, the strength of the strong base and the polarity of the reaction solvent have a great impact on the reaction, so careful selection should be made.
    Each preparation method has its own advantages and disadvantages. In practical application, the most suitable method should be selected according to the comprehensive consideration of various factors such as the availability of raw materials, cost, and product purity requirements.
    What is the price range of 3- (Methylthio) thiophene in the market?
    3 - (Methylthiophene) thiophene is in the market, but its price cannot be determined. The price of the market often changes due to the purity of the quality, the amount of supply, and the urgency of demand. If the quality is pure and the supply is slow, the price may be cheap; on the contrary, if the quality is miscellaneous and the supply is small and the demand is urgent, the price will be high.
    In the past, this product was used more and more widely in the field of chemical industry. However, the amount of its production also affects its price. If the market is full of goods, the price will stabilize and or drop; if the product is poor, the goods will be expensive and the price will rise.
    In addition, the distance of the land and the difficulty of transportation are also related to the price. If the place of origin is close and convenient, the cost will be saved and the price will be suitable; if the place of origin is far away and difficult to transport, the cost will increase and the price will be high.
    Therefore, in order to know the exact price of 3- (methylthiothiophene) thiophene, it is necessary to observe the market conditions, the quality of the quality, the situation of transportation and other factors in order to obtain a more accurate value. The market is not constant, and the price is not fixed. It is difficult to say the scope of its price.