3 Methylbenzothiophene 2 Carboxylicacid
quinoline thiophene imidazole thiazole

3-Methylbenzothiophene-2-carboxylicacid

Taiy Chemical

    Specifications

    HS Code

    555204

    Name 3-Methylbenzothiophene-2-carboxylic acid
    Molecular Formula C10H8O2S
    Molecular Weight 192.234 g/mol
    Appearance Solid (usually white to off - white)
    Melting Point 192 - 196 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
    Pka Around 3 - 4 (approximate, for carboxylic acid group)

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    General Information
    Where to Buy 3-Methylbenzothiophene-2-carboxylicacid in China?
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    Frequently Asked Questions

    As a leading 3-Methylbenzothiophene-2-carboxylicacid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-Methylbenzothiophene-2-carboxylic acid?
    3-Methylbenzothiophene-2-carboxylic acid, which has a wide range of uses. In the field of medicine and chemical industry, it is a key organic synthesis intermediate. It can participate in the construction of a variety of drug molecules through specific chemical reaction steps, which is of great significance for the development of drugs with specific biological activities and therapeutic effects.
    In the field of materials science, it also shows unique value. Due to its structural properties, it may be used to prepare materials with special photoelectric properties. In the field of organic photoelectric materials, such as organic Light Emitting Diode (OLED), solar cells, etc., it may be rationally designed and modified to give materials better properties, thereby improving the efficiency and stability of devices.
    In addition, in the fine chemical industry, it is often used as an important raw material to synthesize various fine chemicals, such as special fragrances, additives, etc., to add unique properties and functions to the product, and to enhance the quality and added value of the product. In short, 3-methylbenzothiophene-2-carboxylic acid plays an indispensable role in many important fields and is of great significance in promoting the development of related industries.
    What are the physical properties of 3-Methylbenzothiophene-2-carboxylic acid?
    3-Methylbenzothiophene-2-carboxylic acid is an organic compound. It has specific physical properties and is described in detail below.
    Looking at its properties, it usually appears solid at room temperature. Its melting point is the key characteristic that determines the state transition of this compound. After many experimental investigations, it can be found that its melting point is within a certain range, and this temperature value is of great significance for the identification and purification of this compound. Due to the different purity of 3-methylbenzothiophene-2-carboxylic acid, the melting point may be slightly different, so the purity can be judged according to the melting point.
    When it comes to solubility, this compound behaves differently in different solvents. In organic solvents such as dichloromethane and chloroform, it has a certain solubility. This property makes it participate in many organic reactions in solution form and is the basis for organic synthesis. However, in water, its solubility is very small. The difference in solubility stems from the difference between the molecular structure of the compound and the interaction force between solvent molecules. Its molecular structure contains benzothiophene ring and carboxyl group. Benzothiophene ring is hydrophobic, while carboxyl group is hydrophilic, but the overall structure makes it difficult to dissolve in water.
    Furthermore, its density is also one of the important physical properties. Density reflects the mass per unit volume of a substance, which is indispensable for the material balance and related process design of the compound. Through accurate experimental measurement, its exact density value can be obtained, providing accurate data support for practical application.
    In addition, the crystal structure of 3-methylbenzothiophene-2-carboxylic acid is also of research value. Its crystal structure is maintained by molecular interactions, such as hydrogen bonds, van der Waals forces, etc. This structure not only affects the physical properties of the compound, but also its chemical properties and reactivity. The crystal structure can be clearly analyzed by X-ray diffraction and other techniques, so as to gain a deeper understanding of the essential properties of the compound.
    In summary, the melting point, solubility, density and crystal structure of 3-methylbenzothiophene-2-carboxylic acid are related to each other, which together constitute the unique physical properties of this substance, laying the foundation for its application in many fields such as organic synthesis and materials science.
    What are the synthetic methods of 3-Methylbenzothiophene-2-carboxylic acid?
    The synthesis method of 3-methylbenzothiophene-2-carboxylic acid has been known in ancient times, and there are many methods, each with ingenuity.
    First, benzothiophene is used as the starting material. First, under specific reaction conditions, it meets with a suitable methylation reagent, so that it successfully introduces methyl at the 3-position of benzothiophene to obtain 3-methylbenzothiophene. Subsequently, the 3-methylbenzothiophene is mixed with a strong oxidizing reagent, and under the appropriate temperature, pressure and reaction time, the oxidation reaction occurs, so that the 2-position is carboxylated, so that 3-methylbenzothiophene-2-carboxylic acid is obtained. In this process, the control of the reaction conditions is extremely critical. The temperature and the amount of reagent will affect the yield and purity of the product.
    Second, it can also start from sulfur-containing aromatic compounds. After a series of carefully designed reaction steps, such as nucleophilic substitution, cyclization, etc., the structure of benzothiophene is gradually constructed, and methyl groups are ingeniously introduced at the 3-position. After the construction of the benzothiophene ring is completed, the carboxyl group is introduced at the 2-position through a suitable carboxylation reaction. This path requires in-depth knowledge of the mechanism and conditions of each step of the reaction to ensure that the reaction proceeds in the expected direction and obtains the ideal product.
    Third, the synthesis strategy of transition metal catalysis can also be used. Appropriate metal catalysts are used with specific ligands to catalyze the reaction of the substrate. In this process, metal catalysts play a key role, which can effectively reduce the activation energy of the reaction and enable the reaction to proceed under relatively mild conditions. Through precise selection of substrates and reaction conditions, efficient synthesis of 3-methylbenzothiophene-2-carboxylic acid is achieved. However, this method requires a high degree of selection and use of catalysts, considering many factors such as catalyst activity, selectivity, and cost.
    Where is 3-Methylbenzothiophene-2-carboxylic acid used?
    3-Methylbenzothiophene-2-carboxylic acid, this substance has a wide range of uses and has its presence in many fields.
    In the field of medicinal chemistry, it is often a key synthesis intermediate. Based on this, compounds with specific biological activities can be carefully prepared, which is very helpful for the development of new drugs. The key to medicinal chemistry lies in the design and synthesis of molecules with precise pharmacological effects, and the unique chemical structure of 3-methylbenzothiophene-2-carboxylic acid can provide a good start for the construction of complex drug molecules, or affect the interaction between drugs and targets, which is related to the quality of drug efficacy.
    In the field of materials science, it can also be traced. Or it can participate in the preparation of polymer materials with special properties. By polymerizing with other monomers, it imparts different properties to the material, such as improving the stability and optical properties of the material. The improvement of material properties is of great significance to the development of many industries. Whether it is high-performance materials used in electronic equipment or special materials for aerospace needs, it may be improved by the participation of 3-methylbenzothiophene-2-carboxylic acid.
    Furthermore, in the field of organic synthetic chemistry, it can be used as an important reagent. Organic synthesis aims to build complex organic molecules, which can play a key role in various reactions, such as participating in carbon-carbon bond formation reactions, functional group conversion reactions, etc., greatly enriching the means and strategies of organic synthesis, enabling chemists to synthesize more organic compounds with novel structures and unique functions, and promoting the continuous development of organic chemistry.
    In summary, 3-methylbenzothiophene-2-carboxylic acid plays an important role in the fields of medicine, materials, organic synthesis, etc., and has a significant impact on the research and development of various fields.
    What is the market outlook for 3-Methylbenzothiophene-2-carboxylic acid?
    3-Methylbenzothiophene-2-carboxylic acid, this product has considerable market prospects today. Looking at the field of chemical materials, its uses are becoming wider.
    In the process of organic synthesis, it is often used as a key intermediate. Nowadays, many new materials are being developed, and the demand for organic compounds with special structures is increasing. 3-Methylbenzothiophene-2-carboxylic acid has a unique structure, which can meet the needs of synthesizing specific functional materials. For the preparation of optoelectronic materials, it may participate in the construction of light-emitting units, which can contribute to the improvement of the performance of optoelectronic devices.
    In the field of pharmaceutical chemistry, it has also emerged. Nowadays, in drug research and development, the pursuit of high-efficiency and low-toxicity new drugs is the general trend. The structure of this compound has been modified, or it can become a leading compound with biological activity, which is the foundation for the creation of new drugs.
    Furthermore, with the concept of environmental protection gradually gaining popularity, green chemical synthesis is heavy. If 3-methylbenzothiophene-2-carboxylic acid can be prepared by green and sustainable methods, it will have more competitive advantages in chemical production. Therefore, in summary, its market prospects are like the rising sun, and it is expected to open up a wide range of fields in the chemical industry, medicine and other fields, and achieve considerable benefits.