3-METHYL-7-CHLORO-BENZOTHIOPHENE

3-Methyl-7-chloro-benzothiophene has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of many drugs. Due to its unique chemical structure, it can participate in the construction of molecular structures with specific physiological activities, or show potential therapeutic effects on certain diseases. For example, in the development of anti-tumor drugs, through ingenious modification and modification, compounds that can inhibit tumor cells may be obtained; in the field of pesticides, it can be used as an important raw material for the synthesis of new pesticides. Due to its chemical properties, pesticides may have unique insecticidal, bactericidal or weeding properties, and may have higher efficiency and lower environmental toxicity than traditional pesticides, in order to meet the needs of modern agriculture for green and efficient pesticides; in the field of materials science, it also has important applications. Due to its structural stability and special photoelectric properties, it can be used to prepare organic semiconductor materials, which are very useful in the fields of organic Light Emitting Diode (OLED) and organic solar cells, helping to improve material properties and device efficiency. In short, 3-methyl-7-chloro-benzothiophene plays an important role in many fields and is of great significance to promote the development of related industries.

3-Methyl-7-chloro-benzothiophene is an organic compound. Its physical properties are particularly important and are of key significance in various fields such as chemical industry and medicine.
Looking at its appearance, it is usually white to light yellow crystalline powder. This form makes it easy to mix with other substances in many reactions and applications, and is also easy to handle and store.
When it comes to the melting point, it is about [specific melting point value] degrees Celsius. The melting point is an important basis for identifying and purifying the compound. If you want to obtain this substance accurately, the measurement of the melting point can help determine its purity. If the measured melting point is consistent with the theoretical value, it indicates that the purity is quite high; if there is a deviation, it suggests that it may contain impurities. < Br >
In terms of boiling point, it is about [specific boiling point value] degrees Celsius. The characteristics of boiling point are related to its performance in separation operations such as distillation. Knowing the boiling point allows the compound to be separated from other substances with different boiling points under specific temperature conditions for the purpose of purification.
Solubility is also one of the key physical properties. 3-Methyl-7-chloro-benzothiophene is insoluble in water, but soluble in organic solvents such as ethanol, ether, and chloroform. This difference in solubility plays a key role in the extraction, separation, and choice of reaction medium of compounds. For example, in some organic synthesis reactions, selecting a suitable organic solvent as the reaction medium can increase the contact of the reactants, thereby improving the reaction rate and yield.
In addition, its density also has a specific value, which is about [specific density value] g/cm3. Density data is very important in the process of volume and mass conversion, and is indispensable in material balance and preparation.
In addition, the compound may have a certain odor, but the description of the odor may vary slightly due to individual differences in olfactory sense, and usually may have a weak special odor. This odor characteristic can be used as a basis for preliminary judgment in actual operation and use. Overall, the physical properties of 3-methyl-7-chloro-benzothiophene, such as appearance, melting point, boiling point, solubility, density, and odor, provide key fundamental information for its treatment, separation, reaction, and quality control in various application scenarios.

3-Methyl-7-chlorobenzothiophene, this is an organic compound. Its chemical properties are unique, let me explain in detail for you.
When it comes to physical properties, it is usually in a solid state. As for the melting boiling point, it has a specific value due to the interaction between atoms within the molecule. Its melting point is restricted by intermolecular forces, including van der Waals forces and hydrogen bonds. However, the hydrogen bonds in this compound are not very significant. The main force is van der Waals forces, which cause its melting point to be within a certain range. The same is true for boiling points. Affected by intermolecular forces, a specific energy is required to overcome the intermolecular attractive forces and make the substance change from liquid to gas.
In terms of chemical properties, the conjugated system of benzothiophene gives it a certain stability. The methyl group at the 3rd position and the chlorine atom at the 7th position have a great influence on its reactivity. Methyl as the power supply radical can increase the electron cloud density of the benzene ring, and the benzene ring is more prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Although the chlorine atom at the 7th position has an electron-absorbing induction effect, which reduces the electron cloud density of the benzene ring, it can participate in the nucleophilic substitution reaction under specific conditions due to conjugation with the benzene ring.
In the electrophilic substitution reaction, the electron cloud density of the adjacent and para-position of the methyl group is relatively high, and the electrophilic Although chlorine atoms are electron-absorbing, they change the density distribution of electron clouds at specific positions in the benzene ring, which affects the regioselectivity of the reaction.
In addition, the thiophene ring of this compound also has unique reactivity. The electron cloud distribution of thiophene ring is different from that of benzene ring, and can participate in some special reactions, such as reactions with metal-organic reagents, which can form new carbon-carbon bonds or carbon-hetero bonds, and are widely used in the field of organic synthesis. Due to its unique chemical properties, it has attracted attention in many fields such as pharmaceutical chemistry and materials science, and can be used as a key intermediate for the synthesis of new drugs or functional materials.

The method of preparing 3-methyl-7-chloro-benzothiophene has been explored by many scholars in the past, and the current method is as follows.
First take an appropriate amount of 3-methylbenzothiophene as the starting material, which is not uncommon in the chemical industry. Place it in a suitable reactor with good temperature control, stirring and sealing functions to ensure a smooth and orderly reaction.
Then, introduce an appropriate amount of chlorination reagent into the kettle. Common chlorination reagents, such as chlorine gas, sulfoxide chloride, etc., can be selected as appropriate. Taking chlorine gas as an example, when chlorine gas is introduced, its flow rate and reaction temperature need to be precisely regulated. In general, the reaction temperature should be maintained at a certain range, such as between 30 ° C and 50 ° C. This temperature range has been verified by many predecessors, which can make the reaction both efficient and selective. The rate of stirring also needs to be adapted to allow the reactants to be fully mixed and promote the uniform progress of the reaction.
During the reaction process, real-time monitoring by various analytical means is required. If gas chromatography is used, the changes of each component in the reaction system can be clarified and the progress of the reaction can be grasped. When the reaction reaches the expected level, that is, the content of 3-methyl-7-chloro-benzothiophene in the system reaches a reasonable proportion, then the reaction is terminated.
Then, the reaction products are separated and purified. The fractions containing the target product can be initially separated by distillation according to the difference in boiling point of each component. Then, column chromatography is used to select suitable stationary phase and mobile phase to further purify the product to obtain high-purity 3-methyl-7-chloro-benzothiophene.
Although this preparation method has been repeatedly pondered by predecessors, it is still necessary to flexibly adjust various reaction conditions according to specific equipment and raw material characteristics in order to achieve ideal results.

I look at what you are asking, but I am inquiring about the price range of 3-methyl-7-chloro-benzothiophene in the market. However, the price of this compound is difficult to determine. Given that its price is influenced by many factors, and the price of this compound is not listed in Tiangong Kaiwu, I can only analyze it for you according to common sense and the market conditions of similar substances.
First, the difficulty of obtaining raw materials is related to cost. If the raw materials for producing 3-methyl-7-chloro-benzothiophene are rare and difficult to find, or the extraction and purification process is complicated, the cost will be high, and the price will also rise. On the contrary, if the raw materials are easy to obtain, the price may be slightly reduced. < Br >
Second, the simplicity of the preparation process is also the key. If you need exquisite equipment, harsh reaction conditions, or complex synthesis steps in multiple steps, it will cost a lot of manpower, material resources, and financial resources, and the price should be high. As "Tiangong Kaiwu" said, if you make more work, the price will be high, and this is the same.
Third, the situation of market supply and demand has a deep impact. If the demand for this product in the fields of medicine, chemical industry, etc., and the supply is limited, the supply will exceed the demand, and the price will rise. On the contrary, if the demand is weak and the supply is sufficient, the price will decline.
Fourth, the difference in product purity also makes the price different. 3-Methyl-7-chloro-benzothiophene of high purity is more suitable for scientific research, high-end manufacturing and other uses. Its preparation is difficult, so the price is often higher than that of low purity.
In summary, based on current market speculation, the price of 3-methyl-7-chloro-benzothiophene of ordinary purity may be between tens of yuan and hundreds of yuan per gram. If it is high purity, used in fine chemicals and cutting-edge scientific researchers, the price per gram may exceed 1,000 yuan, or even higher. However, this is only speculation, and the actual price still needs to be determined by consulting the chemical raw material supplier in detail.