3 Fluorothiophene 2 Carboxylic Acid
quinoline thiophene imidazole thiazole

3-Fluorothiophene-2-carboxylic acid

Taiy Chemical

    Specifications

    HS Code

    244641

    Chemical Formula C5H3FOS
    Molecular Weight 130.14
    Appearance Solid (usually white to off - white)
    Melting Point Typically in the range of 130 - 135°C
    Solubility Soluble in some organic solvents like DMSO, DMF, less soluble in water
    Pka Around 3 - 4 (approximate value for the carboxylic acid group)
    Density Data may vary, but estimated around 1.4 - 1.5 g/cm³
    Stability Stable under normal conditions, but sensitive to strong oxidizing agents and bases

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    General Information
    Where to Buy 3-Fluorothiophene-2-carboxylic acid in China?
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    Frequently Asked Questions

    As a leading 3-Fluorothiophene-2-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 3-fluorothiophene-2-carboxylic acids?
    3 - Wei - 2 - In the chemical analysis, this property can be used to mask gold seeds and eliminate the dryness of their analysis results; in the field of water treatment, it can prevent gold seeds from forming sedimentation in water, which plays the role of water melting.
    Third, the oxidative property is original. Some carbon atoms in the citric acid molecule are in the middle of the citric acid molecule, so under specific conditions, they are both oxidizing and original. However, their oxidative or original properties are usually not very prominent. However, in some oxidative systems, citric acid can be used as a reactant or catalyst, and can be reactant.
    Fourth, esterification reactance. The carboxyl group in the citric acid molecule can be esterified and reversed to form citric acid esters. This ester is often used in plastic plasticization and other fields, and can improve the flexibility and plasticity of plastics.
    Therefore, the general chemical properties of citric acid make it widely used in many fields such as food, medicine, and chemical industry. It is important for daily life.
    What are the main uses of 3-fluorothiophene-2-carboxylic acid?
    3 - Pear 2 - The main use of acid is multi-end.
    Pear pear, its taste is sweet and the sex is low. It can be eaten raw to relieve thirst from dryness, and the body fluid is produced to nourish dryness. And the sex can be cleared, and it is beneficial to those who have symptoms, such as coughing in the lungs and throat. It can also be eaten. It is compatible with rock sugar, lily, etc., and has an excellent effect on nourishing the lungs and relieving cough. In addition, the pulp of Pear, chewing the residue, tastes very good when eaten, and is a good fruit that people like to eat.
    As for acid, its use is also wide. Acid can be added to the body, with the power of the body and the body. In ancient books, it is often reflected in its body. In the compatibility of the body, it can make the body and the body play together to help each body better. And the acid has the effect of nourishing the spleen and the stomach. For those who have a weak spleen and stomach and who eat less stools, they can manage the spleen and stomach and increase their food intake. In addition, the acid can also be used for some health prescriptions, such as the compatibility of the body and the body, which can increase the power of the body, help to support the correction and consolidate the root, and improve the integrity of the person, so as to resist the invasion of external evil.
    In short, Huazhou pear is a good product for food and nourishment due to its effect of clearing the body and promoting the lungs; Acid is an important use in the field of health and health due to its ability to improve the spleen, benefit the stomach and correct the stomach. Both of them have an indispensable position in the aspects of people's livelihood, such as food and nutrition.
    What are the synthesis methods of 3-fluorothiophene-2-carboxylic acid?
    To make tripentanone-2-heptanoic acid, there are many methods, each with its own advantages. The following is a detailed description of Jun.
    First, monoethyl heptanoic acid is used as the beginning, and it is condensed by Dickman's method. Under the action of strong bases such as sodium alcohol, monoethyl heptanoic acid undergoes intramolecular condensation to form a ring to obtain ethyl 2-carbonyl cyclopentyl carboxylate. After hydrolysis and decarboxylation, tripentanone-2-heptanoic acid can be obtained. In this process, when condensation, the amount of base and the reaction temperature need to be precisely controlled, otherwise the yield will be affected. The conditions for hydrolysis and decarboxylation are also critical. If the temperature is too high or too low, the product can be impure.
    Second, 2-pentanone and ethyl acrylate are used as materials, and the series reaction of Michael addition and Clyson condensation is carried out. The carbonyl α-hydrogen of 2-pentanone is active. Under the catalysis of alkali, Michael addition can occur with ethyl acrylate to obtain the addition product. After the product is condensed by Clyson, the carbon-carbon bond and carboxyl structure are constructed, and the target product is obtained. In this path, the choice of base is quite important, and the catalytic activity and selectivity of different bases are different. And during the reaction process, the stability of the intermediate also needs to be paid attention to to to prevent side reactions from occurring.
    Third, ethyl acetoacetate is based on 1,5-dibromopentane. First, ethyl acetoacetate is reacted with sodium alcohol to form enolate negative ions, and then nucleophilic substitution occurs with 1,5-dibromopentane to grow the carbon chain. After hydrolysis, decarboxylation and keto decomposition, tripentanone-2-heptanoic acid can be prepared. In this process, the selectivity of nucleophilic substitution should be paid attention to, because dibromopentane has different reaction check points or causes by-products to form. The conditions of hydrolysis and decarboxylation also have a significant impact on the purity and yield of the product. < Br >
    All these methods have their own advantages and disadvantages. In actual operation, careful selection is made according to the availability of raw materials, the difficulty of reaction conditions, the purity and yield of the product, and many other factors to achieve the best preparation effect.
    What are the precautions for 3-fluorothiophene-2-carboxylic acid during storage and transportation?
    When it comes to trinitroglycerin and diglycerin, it is necessary to be careful when it is stored and stored.
    The most important thing is the control of the degree. These two are sensitive, and it is easy to cause emotions when it is high. It is appropriate to use a place where it is comfortable to pass, so as not to be in a place of inflammation, which will cause the degree to exceed the safe limit, cause decomposition, etc., and cause the danger of explosion.
    The prevention of secondary earthquakes. When these two things encounter strong earthquakes, they are also easy to stimulate the reaction, causing the elephant to live. Therefore, if you are in trouble, you should seek peace on the road, and avoid the rough and bumpy road. If you are in trouble, you should also be safe in the solid, and do not let the earthquake happen.
    Furthermore, the source of fire is separated. Both are flammable and explosive, so the surrounding area is not a source of fire. Open flames, or sparks from the device, etc., are inaccessible to prevent ignition and detonation, resulting in a large explosion.
    And there is an anti-rot. Diacid glycerin is corrosive, and the container of the container must be anti-corrosive materials, such as special gold or plastic, and it is well-packed to prevent it from leaking and rotting the surrounding things, and it is also protected from people.
    In addition, the amount of is also. Depending on the safety of, set a reasonable amount, do not stock up too much, resulting in a large increase in. And it is appropriate to divide and store, it is easy to manage and prevent.
    Therefore, trinitroglycerin and diglycerin should be stored and stored, and all things should be paid attention to to to ensure safety.
    What is the market price of 3-fluorothiophene-2-carboxylic acid?
    3-Hydroxyproline-2-carboxylic acid is on the market, but its price is difficult to determine, due to various factors, such as the quality of the good or bad, the situation of supply and demand, the preparation process and the market pattern.
    If its quality is high, impurities are few, and the preparation method is exquisite, the cost is high, and the price is also high. However, if the quality is average, the preparation process is ordinary, and the market supply is sufficient, and the demand is not seen, the price may become more affordable.
    Looking at the current market, such compounds are mostly used in pharmaceutical research and development, biochemical research and other fields. In pharmaceutical research and development, because of its unique use in biological activity, pharmacological properties, etc., it is related to the efficacy and safety of drugs, so the quality requirements are strict, and its price is correspondingly higher. In biochemical research, as an important biochemical reagent, it also has specific requirements for purity, stability and other indicators, which also affects its market price.
    Roughly speaking, its market price is between tens of yuan and hundreds of yuan per gram. If it is high purity and special specifications, the price may exceed. However, this is only an approximate number, and the actual price often changes from time to time and varies from market to market. When the market changes, it is advisable to scrutinize the market conditions and compare suppliers to obtain a more appropriate price to meet your own needs and save costs.